The following plot represents the hierarchical landscape of 'ABC transporters - Homo sapiens (human)'. The hierarchical tree allows to click on the pathways with children (black border) and continue the exploration. All nodes are colored by their source (click on the map for the legend) and cross-link to the original pathway page.

• reactome   Mitochondrial ABC transporters

• reactome   Defective ABCC8 can cause hypoglycemias and hyperglycemias
• reactome   Defective ABCC2 causes Dubin-Johnson syndrome
• reactome   Defective ABCG5 causes sitosterolemia
• reactome   Defective ABCD4 causes methylmalonic aciduria and homocystinuria, cblj type (MAHCJ)
• reactome   Defective ABCB11 causes progressive familial intrahepatic cholestasis 2 and benign recurrent intrahepatic cholestasis 2
• reactome   Defective ABCC6 causes pseudoxanthoma elasticum (PXE)
• reactome   Defective ABCC9 causes dilated cardiomyopathy 10, familial atrial fibrillation 12 and hypertrichotic osteochondrodysplasia
• reactome   Defective ABCG8 causes gallbladder disease 4 and sitosterolemia
• reactome   Defective ABCB4 causes progressive familial intrahepatic cholestasis 3, intrahepatic cholestasis of pregnancy 3 and gallbladder disease 1
• reactome   Defective ABCD1 causes adrenoleukodystrophy (ALD)
• reactome   Defective ABCA12 causes autosomal recessive congenital ichthyosis type 4B
• reactome   Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)
• reactome   ABC transporter disorders
• reactome   Defective ABCA1 causes Tangier disease
• reactome   Defective ABCA3 causes pulmonary surfactant metabolism dysfunction 3 (SMDP3)
• reactome   ABC transporters in lipid homeostasis
• reactome   Defective ABCA3 causes pulmonary surfactant metabolism dysfunction type 3 (SMDP3)
• reactome   ABC-family proteins mediated transport