PI3K-Akt Signaling Pathway - Pathway Page
Name PI3K-Akt Signaling Pathway
Resource WikiPathways
Genes EGF PTEN THBS4 MYB CDKN1A VEGFB CCNE2 FGF10 CSHL1 FGF18 IFNA5 FGF3 CREB3L3 BRCA1 IFNA16 ITGA9 MIR3652 FGF20 ITGB1 CHUK ITGA7 RAF1 TSC1 CD19 COL4A6 GHR IFNA17 ITGA4 PRL PDGFRB IL2RB SGK2 NTRK1 BDNF PIK3R1 VEGFD IRS1 IFNA4 AKT3 LAMC2 EFNA3 VTN PIK3CB FN1 LAMB3 TLR2 PTK2 ITGB5 PPP2R2D FGF13 GNG5 IL7R NTRK2 RPTOR PKN1 GNG12 ITGB3 COMP VWF G6PC IFNA13 TSC2 GNG13 EPOR IBSP NOS3 PRLR HSP90AB1 INSR KRAS ITGA2 CREB5 ITGA2B LPAR2 THBS1 ANGPT4 PCK1 CREB1 BCL2L1 MAPK3 EFNA2 MIR1181 COL4A1 STK11 PIK3R5 COL6A1 CREB3 PPP2R3A PPP2R5A COL4A2 RBL2 COL9A2 CCNE1 CDK4 COL6A6 LAMA4 GNG7 GNB3 IGF2 TNC IFNA2 DDIT4 MAP2K1 NRAS PPP2R2A PPP2R5D GNG2 SYK LPAR1 EFNA4 PDPK1 SOS2 FGF12 IFNA10 FGFR1 FGFR3 COL6A5 CSH2 GNB2 IL2RA SGK3 TCL1B PHLPP2 CDKN1B GNG10 RPS6KB2 IL3 IFNA21 GNG11 MET MAPK1 COL6A3 FGF1 FGF7 PPP2R2B VEGFC PPP2R3C BCL2 THBS3 NTF3 CREB3L2 EIF4E2 EPHA2 LAMA2 GNG4 HRAS KIT JAK2 LAMC3 EFNA5 MDM2 EGFR TGFA FGFR2 TNXB G6PC2 PHLPP1 INS CSF3 CDK6 FGF8 EIF4EBP1 RELA LAMB4 SOS1 CSH1 NGFR PPP2CB PIK3R6 IGF1 TNN SPP1 CCND1 ITGB8 MYC AKT2 PKN2 IL2RG KDR KITLG EIF4B EIF4E1B TP53 IFNA8 MIR4260 PIK3R2 TCL1A IL3RA CSF1R RELN NFKB1 PPP2CA FGF21 SGK1 CDK2 ANGPT1 FASLG EFNA1 RPS6KB1 FGF9 BAD TEK LAMB1 COL1A2 LAMB2 ITGA1 PGF ANGPT2 COL9A1 FGFR4 JAK3 PRKAA1 ITGA10 COL4A4 GRB2 GH1 FGF4 GYS2 PCK2 PPP2R2C LAMC1 PDGFC IFNB1 PDGFD EPO PPP2R1B FGF14 ITGA6 FGF22 ATF2 PDGFB IGF1R TLR4 LPAR4 MLST8 RAC1 PPP2R3B CREB3L4 MTOR COL4A3 IFNAR2 PPP2R5B GNGT2 IFNA1 ITGB6 THBS2 MIR4758 PIK3CG NTF4 LINC02478 FLT1 FGF23 IKBKB LPAR5 CCND3 PPP2R5E AKT1 LAMA1 IL6 IL4R IKBKG JAK1 GNB4 CREB3L1 GNB1 THEM4 FGF5 NGF PDGFA ATF4 ITGAV COL9A3 HSP90AA1 LAMA3 IL4 OSM HGF ATF6B HSP90B1 PKN3 ITGB7 COL6A2 PRKAA2 IFNA14 PPP2R1A PIK3AP1 G6PC3 PIK3CD FGF19 IFNA7 IL7 CHRM1 GNGT1 TNR CHAD F2R CHRM2 MAP2K2 COL4A5 GNG8 FGF2 GNB5 GNG3 FLT4 IL2 MCL1 CDC37 LPAR6 OSMR FLT3 GYS1 COL1A1 CCND2 PIK3CA RHEB PDGFRA FGF17 CSF1 FLT3LG IFNA6 GH2 BCL2L11 GSK3B RPS6 C8orf44-SGK3 VEGFA LPAR3 PPP2R5C EIF4E IL6R PIK3R3 ITGA3 CSF3R IFNAR1 FOXO3 FGF11 ITGA5 ITGA11 PRKCA FGF6 LAMA5 CASP9 ITGB4 ITGA8 COL2A1
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Hierarchy Landscape

The following plot represents the hierarchical landscape of 'PI3K-Akt Signaling Pathway'. The hierarchical tree allows to click on the pathways with children (black border) and continue the exploration. All nodes are colored by their source (click on the map for the legend) and cross-link to the original pathway page.

Equivalent Pathways
Sub-Pathways

About

ComPath is developed and maintained in an academic capacity by Daniel Domingo-Fernández and Charles Tapley Hoyt at the Fraunhofer SCAI Department of Bioinformatics. This web application relies on data loaded from KEGG, Reactome, and WikiPathways Restful APIs, as well as MSigDB. More information here.