PI3K-Akt Signaling Pathway - Pathway Page
Name PI3K-Akt Signaling Pathway
Resource WikiPathways
Genes COL4A3 PRKAA2 FGF12 PIK3CA PKN1 RPS6KB1 CHRM1 CSF3 ITGB7 PRKAA1 IKBKB FGFR2 TSC2 PRLR AKT1 EFNA5 CREB5 PIK3R1 NOS3 BCL2 CCNE1 IL2 COL4A2 MAP2K2 RPS6KB2 COL9A2 CCNE2 VEGFB RAF1 EIF4E LAMB1 SGK2 LPAR1 GNB2 PDGFC MAPK1 CHAD FGF7 IL7R PPP2R5E LAMB3 THBS2 FGF5 CSH2 PIK3CG ITGA3 EGF PIK3R2 COL9A3 FGF18 MLST8 CSF1 ITGA7 TNC CSH1 ANGPT4 IFNA10 IFNA4 ITGB6 IL4R RPS6 MYC GNG5 CSF3R SYK CSF1R GNG4 EFNA2 ITGA11 COL6A6 FLT3LG FGF23 LAMA3 EFNA3 EFNA4 LAMC1 EIF4EBP1 NRAS EPO CDKN1A BCL2L11 ITGB3 COL1A2 MCL1 NGFR GNG2 PDGFRA IL2RB LAMB2 GH1 MAP2K1 GNGT1 FGF13 PGF CREB1 HGF IBSP GRB2 RBL2 THBS1 CCND1 ITGB8 PCK2 PPP2R5B OSMR COL4A6 PDGFB PPP2R2D FGF17 GNB3 IGF1R ITGB4 PIK3CD GNB1 ITGAV GNB4 LAMC2 IL4 MDM2 IFNA6 VTN FLT1 ITGA1 COL9A1 GYS2 PPP2R2B IFNA17 AKT2 FLT3 CSHL1 IL2RG LPAR6 COL4A5 MYB ITGA2 GNB5 SGK3 IFNA14 G6PC2 FGF19 GYS1 PPP2R5D THBS4 NGF FGF14 PDGFA CHRM2 DDIT4 ANGPT2 JAK1 FGFR3 ATF6B CREB3L2 PPP2R3A COL4A4 IL7 EIF4E2 MET CCND2 OSM PHLPP1 INSR PPP2R5A VEGFD IFNB1 PRKCA PPP2CA FN1 CASP9 PRL FGF10 IFNAR2 FGF1 PIK3R6 KRAS LAMC3 CREB3L3 HSP90AB1 ITGA9 MIR4758 FGFR1 LPAR2 FGF6 EIF4B NFKB1 EGFR ITGA2B BAD PIK3AP1 MIR1181 IFNA2 SPP1 GNGT2 F2R ITGA4 SOS1 FLT4 LAMA4 KIT COL6A5 LPAR4 VEGFA IL3 RELA FGF11 FGF21 ITGB5 G6PC3 LAMA2 GH2 LAMB4 C8orf44-SGK3 FGF4 ATF4 PHLPP2 ATF2 CREB3L4 CREB3 GNG13 GNG3 MTOR PDGFD PKN2 IFNA5 TEK THBS3 COL4A1 PPP2R3C COL1A1 TCL1A FOXO3 ITGA10 CDKN1B THEM4 EPOR TGFA GHR AKT3 LAMA5 IFNA7 IFNA1 EPHA2 IL3RA LAMA1 FGF22 PCK1 COL2A1 TCL1B CDK6 IKBKG PTK2 RAC1 CHUK CDK2 LPAR5 RPTOR HRAS SOS2 IFNA16 INS PKN3 LINC02478 TSC1 GNG7 FGF3 PPP2R1B GSK3B FGF20 FGF8 RHEB PPP2R2C PPP2R2A PIK3R3 KITLG FASLG MAPK3 ANGPT1 G6PC BDNF GNG8 NTF4 PPP2CB TLR2 RELN PTEN ITGB1 LPAR3 KDR CCND3 BRCA1 COL6A2 MIR4260 TNR FGF2 IRS1 NTRK2 FGF9 HSP90B1 COL6A1 PIK3CB ITGA5 IFNA21 IFNA13 IL6R CREB3L1 PPP2R3B TNXB CD19 GNG12 BCL2L1 PIK3R5 STK11 COL6A3 NTRK1 EFNA1 CDC37 IFNA8 TLR4 NTF3 IFNAR1 PPP2R5C JAK3 PPP2R1A ITGA6 JAK2 COMP IL6 VWF GNG10 PDGFRB TNN ITGA8 MIR3652 EIF4E1B IL2RA IGF2 IGF1 HSP90AA1 SGK1 GNG11 PDPK1 CDK4 TP53 VEGFC FGFR4
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Hierarchy Landscape

The following plot represents the hierarchical landscape of 'PI3K-Akt Signaling Pathway'. The hierarchical tree allows to click on the pathways with children (black border) and continue the exploration. All nodes are colored by their source (click on the map for the legend) and cross-link to the original pathway page.

Equivalent Pathways
Sub-Pathways

About

ComPath is developed and maintained in an academic capacity by Daniel Domingo-Fernández and Charles Tapley Hoyt at the Fraunhofer SCAI Department of Bioinformatics. This web application relies on data loaded from KEGG, Reactome, and WikiPathways Restful APIs, as well as MSigDB. More information here.