PI3K-Akt Signaling Pathway - Pathway Page
Name PI3K-Akt Signaling Pathway
Resource WikiPathways
Genes PHLPP1 FGF7 JAK1 FGFR4 PKN1 THBS1 COMP COL4A4 SGK1 GNG5 GNG2 RPS6KB1 FGF6 NTF3 CDC37 PIK3R2 THBS2 GNG3 TLR4 GNG13 LAMA3 LPAR5 LAMC3 TSC1 FGF17 TLR2 PTEN PIK3CB IFNA1 TEK IKBKG IFNAR2 IL2RG LPAR6 KITLG ITGB1 CDK4 NOS3 COL4A1 ITGA11 LAMC1 TGFA NGF TNXB PHLPP2 ANGPT1 PIK3CD CDK6 PRKAA2 PIK3CG C8orf44-SGK3 EFNA2 STK11 G6PC3 CSF1 PPP2R1B IL7 CREB3 NTRK2 LPAR4 PIK3AP1 ITGA2B IFNB1 COL1A1 KRAS BCL2L11 FGF19 CREB3L4 INSR EFNA3 HGF IFNA16 COL6A3 PPP2R5E PPP2CA MAPK1 ITGB4 AKT2 GNG4 IL3 ITGA8 LAMA1 LPAR3 CREB3L3 CHRM2 ITGB7 PDPK1 GNGT1 NFKB1 HSP90B1 CCNE2 FGF4 GNG8 ITGA7 ITGA9 G6PC EIF4E GNB2 FGF20 GNB5 COL9A3 FLT1 PPP2R2C GYS1 PTK2 EFNA4 EIF4EBP1 PKN2 EIF4E1B PRLR COL4A6 MIR4758 GSK3B TNN FGFR2 PPP2R2D IFNA7 CREB1 PPP2R5D GNB1 IFNA21 HSP90AA1 COL6A6 VEGFB FGF5 MIR4260 MAP2K2 CHUK PIK3R5 EPO TCL1A RPTOR CSF3R FGFR3 CHRM1 SOS1 IL2RB BAD BRCA1 HSP90AB1 INS MAPK3 FGF22 IGF2 PIK3R1 FGF1 ANGPT2 OSMR BCL2L1 MLST8 CCND1 EGFR CSF3 ITGB6 HRAS PCK2 ITGAV FN1 PDGFC ITGB5 FLT4 SPP1 COL6A5 VEGFD THBS4 SOS2 F2R GNG10 ITGA6 GYS2 GNG12 NTF4 GH2 FOXO3 PIK3CA LINC02478 FGF12 MIR3652 RAF1 VWF LAMA5 IKBKB ITGA4 IFNA13 RELA FLT3 MYB ITGA2 EGF PPP2R5A LPAR2 MTOR IL7R KIT GNB4 CHAD IFNA8 TSC2 GNG11 ITGB8 ITGB3 COL4A3 PPP2R2B JAK3 GNG7 FGF3 LAMA4 PRL FLT3LG IFNA17 OSM ATF2 MET FGF14 IGF1 FGF2 LAMC2 IFNA6 PPP2R5C MDM2 ATF6B RPS6 CDKN1B COL6A2 COL9A1 FASLG THBS3 PDGFB LAMB4 PGF TP53 IL4R CDKN1A TCL1B LAMB3 CSHL1 PDGFA PRKAA1 IRS1 RBL2 SGK2 CCNE1 ITGA5 FGF9 NTRK1 NRAS PIK3R3 PPP2R3B AKT1 IFNA5 LPAR1 CDK2 NGFR CSF1R RHEB PCK1 GHR IL4 ITGA1 PIK3R6 IL3RA RPS6KB2 LAMB1 JAK2 EFNA5 FGF10 PPP2R1A IL6 COL6A1 FGF11 AKT3 EPHA2 PKN3 EIF4E2 TNR COL9A2 IFNA10 SYK GNB3 EIF4B VEGFC CREB5 PPP2R5B COL2A1 DDIT4 FGFR1 GNGT2 EFNA1 MYC IFNA14 COL4A2 PDGFRB CSH2 RAC1 CASP9 BDNF MCL1 IL2RA LAMB2 FGF13 IFNA4 IBSP BCL2 MIR1181 COL4A5 FGF18 PPP2R2A KDR VTN CREB3L1 IFNA2 EPOR VEGFA FGF21 MAP2K1 SGK3 IL2 CSH1 FGF8 IFNAR1 FGF23 COL1A2 IGF1R CD19 PDGFRA ITGA10 TNC CCND3 RELN ATF4 PRKCA CREB3L2 ANGPT4 ITGA3 GH1 GRB2 G6PC2 PDGFD CCND2 LAMA2 PPP2CB PPP2R3C IL6R THEM4 PPP2R3A
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Hierarchy Landscape

The following plot represents the hierarchical landscape of 'PI3K-Akt Signaling Pathway'. The hierarchical tree allows to click on the pathways with children (black border) and continue the exploration. All nodes are colored by their source (click on the map for the legend) and cross-link to the original pathway page.

Equivalent Pathways
Sub-Pathways

About

ComPath is developed and maintained in an academic capacity by Daniel Domingo-Fernández and Charles Tapley Hoyt at the Fraunhofer SCAI Department of Bioinformatics. This web application relies on data loaded from KEGG, Reactome, and WikiPathways Restful APIs, as well as MSigDB. More information here.