PI3K-Akt Signaling Pathway - Pathway Page
Name PI3K-Akt Signaling Pathway
Resource WikiPathways
Genes MAP2K2 FLT1 PTK2 ANGPT2 RPS6KB1 TNC FGF8 RPTOR FGF4 FGF6 COL6A5 FGF12 PIK3AP1 RHEB TGFA PPP2R3A PPP2CA ITGB6 BRCA1 CREB3L4 THBS4 IL3 CDK2 LAMC3 PDGFC COL1A2 IL2RA IL2 G6PC2 EGFR COL6A2 VEGFA RPS6KB2 IFNA2 RELA CCNE2 MYB FGF13 PDGFD EFNA5 OSM CDK6 MDM2 PPP2R3B EFNA3 COL6A3 NTF3 VEGFB JAK3 ITGA2B IFNAR2 NTRK2 IGF2 THBS1 RAC1 PKN2 BCL2L1 CCND2 IGF1R CREB1 SYK EPOR MIR1181 PIK3CB MET FGF1 PPP2CB COL2A1 LPAR3 FGF22 FGFR3 EFNA2 G6PC TP53 IL6R PIK3CD RBL2 FASLG CHRM1 MIR4260 MIR3652 EPO AKT1 NGF INSR GNB2 THBS2 IKBKG IFNA5 FGFR4 ITGB3 VWF PIK3R5 CDK4 CDKN1B PPP2R5C VEGFC VTN COL6A1 ITGA3 KIT LPAR5 PPP2R2A SGK1 PKN1 ITGB7 TNR LAMC2 CSH1 FGF7 CSHL1 LAMA4 ITGA1 FGF14 BCL2 IFNA21 IBSP ITGB1 MLST8 CSF1R FGF17 IFNA1 COL4A3 ITGA6 MAPK3 GRB2 SPP1 COL4A2 COL6A6 G6PC3 IFNA17 LPAR4 KITLG NFKB1 GNB5 FGF2 PRKAA1 CHUK ITGA10 GNG3 GNG5 COL4A6 ATF6B ITGA7 PCK1 MYC SGK3 HRAS GNG13 IL3RA GNG8 SGK2 TLR2 PHLPP1 SOS2 CSH2 PDGFRB IKBKB EFNA4 IL2RG EPHA2 HGF PCK2 FLT3 ANGPT1 ATF4 EGF CDC37 FN1 IL6 ITGA9 TCL1A LPAR2 FGF21 CDKN1A IFNA7 IFNA8 TEK MIR4758 SOS1 TNN KDR LAMB1 ITGB5 FGF18 EIF4EBP1 GYS2 CHRM2 COL9A1 CREB3L2 KRAS IFNA6 TSC2 GNB1 LPAR6 IFNA4 FGF9 ITGA4 PDPK1 FGF11 COL9A2 IFNA10 HSP90AB1 GNB3 PIK3R3 CSF3R NOS3 LAMB2 JAK2 PRLR PDGFB IL7 HSP90AA1 IL4R COL4A4 CSF1 PPP2R2D LAMC1 PIK3CG FGF3 GSK3B COMP GNB4 PPP2R5D BCL2L11 THBS3 EIF4E2 COL4A1 AKT3 FLT4 GYS1 IRS1 C8orf44-SGK3 MCL1 NGFR PRKCA ATF2 PPP2R5A PPP2R1A PIK3CA LAMA3 PPP2R5B GH2 DDIT4 IL7R CD19 IFNA14 IL4 TCL1B ANGPT4 IL2RB PIK3R2 PPP2R1B IFNB1 NTF4 TNXB COL4A5 COL9A3 LAMA2 FGF20 ITGB8 ITGA11 FLT3LG GNG10 PPP2R2B LAMA5 GHR CREB3L1 PKN3 F2R MTOR NTRK1 FGF19 BAD LAMB3 MAP2K1 PTEN IFNA16 RELN STK11 FGF10 CCNE1 IFNA13 TSC1 PPP2R2C PHLPP2 GNG4 CCND1 PIK3R6 LAMA1 COL1A1 JAK1 INS GNG7 EIF4E ITGAV GH1 RAF1 ITGA5 FOXO3 CREB3 THEM4 OSMR PRKAA2 PIK3R1 GNGT2 ITGA8 PDGFA CHAD GNGT1 FGFR1 CSF3 PPP2R3C LAMB4 IGF1 FGF5 LPAR1 CASP9 GNG2 PDGFRA GNG11 PPP2R5E IFNAR1 VEGFD EFNA1 CCND3 PRL PGF FGF23 BDNF RPS6 EIF4E1B ITGB4 CREB3L3 ITGA2 CREB5 AKT2 EIF4B HSP90B1 NRAS FGFR2 TLR4 GNG12 MAPK1 LINC02478
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Hierarchy Landscape

The following plot represents the hierarchical landscape of 'PI3K-Akt Signaling Pathway'. The hierarchical tree allows to click on the pathways with children (black border) and continue the exploration. All nodes are colored by their source (click on the map for the legend) and cross-link to the original pathway page.

Equivalent Pathways
Sub-Pathways

About

ComPath is developed and maintained in an academic capacity by Daniel Domingo-Fernández and Charles Tapley Hoyt at the Fraunhofer SCAI Department of Bioinformatics. This web application relies on data loaded from KEGG, Reactome, and WikiPathways Restful APIs, as well as MSigDB. More information here.