PI3K-Akt Signaling Pathway - Pathway Page
Name PI3K-Akt Signaling Pathway
Resource WikiPathways
Genes COMP MIR4260 CSF1R GNB1 RPS6 COL2A1 FGF14 LAMB3 ITGA9 PCK1 IKBKG PPP2R5B GNG12 TEK FGF12 RBL2 MIR3652 GNG3 ANGPT2 FGF22 IL2RB PPP2R1A PRKCA CREB3L4 IFNA16 PPP2R5E CREB5 HSP90AA1 VEGFA MTOR AKT2 IFNAR1 GYS1 IFNA2 PPP2R3B GNB4 JAK2 EPOR LAMC3 MDM2 COL6A6 TNR LPAR1 NFKB1 TNN CHUK LAMA2 IFNA8 PHLPP2 CSHL1 CSF3R CCNE1 G6PC3 CDC37 ITGA6 NOS3 FGF18 FGF17 NTF4 CSH1 IRS1 TP53 G6PC2 CSH2 OSMR ITGA5 MAP2K2 FN1 IKBKB PIK3R3 LAMA5 GNG5 PPP2R2D FGF19 PPP2R2A PGF VEGFC SGK3 EGF RAF1 ANGPT4 CD19 LPAR3 LAMA4 PIK3R5 LPAR6 GH1 ITGB4 ATF4 MCL1 PPP2CA FASLG EFNA5 FLT4 JAK1 IL4R VEGFB RAC1 COL6A1 PIK3R1 TGFA COL4A2 NTRK1 PRLR FGFR1 TLR4 COL9A1 AKT1 CDKN1B GSK3B GNB5 IL7R EIF4EBP1 FGF3 FLT1 VWF EPHA2 PDGFC MIR1181 TNC RPS6KB2 HSP90B1 CCND1 NGFR CSF1 DDIT4 RPS6KB1 PDPK1 GYS2 FGF6 LINC02478 EFNA3 LAMC2 LAMB2 MET FLT3LG CDKN1A FGFR4 FGF20 KDR SGK1 IGF1R TNXB ITGB3 PDGFRA ITGA10 GNG10 GNG8 VEGFD TCL1A COL4A4 IL2RA THBS1 IFNA1 ITGA4 HGF FGF10 SPP1 COL4A6 ITGB8 BCL2 PPP2R1B PTK2 PIK3CB EIF4E2 FGF21 EIF4E1B EFNA1 PRL FGF2 IFNB1 CCND2 RELA SGK2 IL3RA PRKAA1 LAMA1 PPP2R3C PKN3 COL6A3 IFNA17 C8orf44-SGK3 MAPK1 IL4 NRAS THBS3 MLST8 COL6A2 PPP2CB JAK3 FGF23 PIK3CD NTRK2 ITGA1 NTF3 TLR2 PIK3AP1 PDGFB G6PC PKN1 MAPK3 COL1A1 PPP2R5A HRAS INS GHR COL4A3 ITGB7 BRCA1 SYK PDGFRB IFNA14 PKN2 IL3 FGF13 PIK3R2 ITGAV PIK3R6 CHAD ATF6B CREB3L2 SOS2 CHRM2 GNG11 HSP90AB1 LPAR2 MYB FGFR2 FOXO3 RPTOR PPP2R2C LPAR4 IL6R BCL2L11 CCNE2 PPP2R3A ITGA8 TSC1 IL7 FGF11 MYC ITGA3 COL4A1 CASP9 EFNA4 KRAS KITLG GNG13 GNB3 IFNA5 RELN FGF7 FGFR3 CREB3 GH2 GNGT2 IL2RG IFNA21 PPP2R2B EIF4B FGF8 CSF3 TSC2 GRB2 STK11 NGF THBS4 IGF1 LAMB1 MAP2K1 BDNF LPAR5 COL4A5 TCL1B IL6 FGF5 EIF4E ITGA7 PPP2R5D CHRM1 OSM FGF9 LAMC1 CCND3 EGFR LAMA3 FGF4 LAMB4 PPP2R5C GNGT1 COL1A2 IFNA13 PCK2 ITGB5 THBS2 CDK6 GNG2 ITGA2 EPO ATF2 IFNA6 AKT3 IBSP GNG7 ITGA2B PRKAA2 MIR4758 ITGB1 IGF2 BCL2L1 PDGFA IFNAR2 F2R CREB3L3 IFNA4 GNB2 RHEB IFNA7 FGF1 CDK2 KIT PDGFD EFNA2 ITGA11 VTN PIK3CA SOS1 CREB1 COL6A5 COL9A3 IFNA10 PHLPP1 THEM4 FLT3 GNG4 CDK4 CREB3L1 INSR PIK3CG IL2 BAD PTEN ITGB6 COL9A2 ANGPT1
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Hierarchy Landscape

The following plot represents the hierarchical landscape of 'PI3K-Akt Signaling Pathway'. The hierarchical tree allows to click on the pathways with children (black border) and continue the exploration. All nodes are colored by their source (click on the map for the legend) and cross-link to the original pathway page.

Equivalent Pathways
Sub-Pathways

About

ComPath is developed and maintained in an academic capacity by Daniel Domingo-Fernández and Charles Tapley Hoyt at the Fraunhofer SCAI Department of Bioinformatics. This web application relies on data loaded from KEGG, Reactome, and WikiPathways Restful APIs, as well as MSigDB. More information here.