PI3K-Akt Signaling Pathway - Pathway Page
Name PI3K-Akt Signaling Pathway
Resource WikiPathways
Genes CDKN1B ITGA3 RAC1 FOXO3 ITGA2B PPP2R3A CSF1 MIR4260 SOS2 PIK3R1 THBS2 KRAS FASLG IFNA7 MYB GSK3B G6PC CREB5 PRKAA1 INS CD19 IL7R GH2 RPS6KB1 VEGFA NFKB1 GNG2 CDC37 FGF7 MAP2K1 PDGFRA CHAD IL3 LAMC1 IL7 TSC1 NRAS PDGFD COMP CDK2 FGF3 PDGFRB NOS3 EIF4EBP1 GNB3 TNC COL6A6 MIR1181 ITGA8 GNG3 LPAR3 COL1A2 COL9A1 ITGB6 EFNA3 PDGFC F2R MLST8 SGK3 HSP90B1 COL6A2 BCL2L1 LAMC2 BAD ATF2 FGF23 LAMB2 LAMB1 EPHA2 CDK6 VEGFC HSP90AA1 RBL2 FLT1 EIF4E EPO CCND2 OSMR CREB3L2 PIK3R6 JAK3 FGF14 IL2RG IFNA6 MIR3652 IFNA2 PRKCA COL4A2 GH1 PKN1 SGK2 CCND3 PPP2R1B FGF9 STK11 TNXB IFNA13 CHUK TCL1B ITGA4 PPP2R5E PHLPP1 INSR CCNE1 IL2RB COL6A1 TCL1A ATF4 MDM2 TNN PPP2R2C IGF1 IFNA21 GNG8 GNG5 PRLR PPP2R2A IKBKB PIK3R3 RELA JAK1 LAMB3 RHEB EIF4B PPP2R5A GNB5 MYC G6PC2 FGFR3 PKN2 PDPK1 THEM4 RELN CSF1R ITGB4 PPP2R3B HSP90AB1 IFNA17 COL9A2 CSF3R IFNB1 PPP2R5C KDR MAPK3 CDK4 RAF1 TP53 NTF4 EPOR PRKAA2 TSC2 TGFA RPS6 FGF20 CREB3L4 CREB3L3 MCL1 IL6 PPP2R5D GNG11 AKT3 GNG13 COL9A3 ANGPT4 FN1 FGF19 PHLPP2 COL6A5 MAPK1 IL3RA IFNAR2 PCK2 PPP2R2B COL4A6 G6PC3 FGFR2 VEGFD THBS1 EGF COL4A3 PDGFA PPP2R2D PCK1 EGFR MET MIR4758 PIK3CD PGF EFNA2 C8orf44-SGK3 GNG7 IL4R GNB1 PIK3R2 EFNA1 IFNA10 KIT COL4A1 ITGA10 NGFR FGF17 ITGB8 BRCA1 LAMA3 GNB4 THBS3 TLR4 EIF4E1B PKN3 CCND1 ITGA11 GNB2 MAP2K2 CCNE2 TNR CSF3 IFNA8 GYS1 FGF11 CASP9 FGF2 COL2A1 FGF5 CHRM1 LAMA1 NTRK1 THBS4 FGFR4 PIK3CA VEGFB GNG10 OSM LPAR2 LAMA5 IFNA1 IGF2 RPTOR ATF6B IFNA5 LINC02478 FLT3 FLT3LG TEK FGF18 ITGA7 CREB3L1 BCL2 ITGA6 CREB1 HGF PIK3CG CHRM2 FGF6 FGF4 LPAR1 LAMC3 FGF8 ANGPT1 GNGT1 IFNAR1 LPAR4 FGF12 DDIT4 VTN IGF1R PPP2R1A IFNA16 LPAR6 MTOR FGF1 IL4 CREB3 ITGAV JAK2 LAMA2 IL2 FGFR1 CDKN1A AKT2 PPP2R5B NGF BDNF ANGPT2 LPAR5 CSH2 FLT4 ITGA9 GRB2 PIK3CB PIK3R5 PDGFB GHR COL4A5 ITGB5 HRAS EIF4E2 ITGA2 GNG12 IKBKG FGF21 IFNA4 EFNA4 PPP2CA RPS6KB2 IL2RA PRL COL6A3 VWF COL1A1 LAMB4 PTK2 COL4A4 FGF22 ITGB1 PPP2R3C GNGT2 SGK1 KITLG NTF3 LAMA4 ITGB7 SPP1 IFNA14 FGF10 PPP2CB CSHL1 SYK IL6R IRS1 ITGB3 SOS1 TLR2 ITGA5 ITGA1 EFNA5 PIK3AP1 FGF13 BCL2L11 GNG4 CSH1 AKT1 PTEN GYS2 IBSP NTRK2
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Hierarchy Landscape

The following plot represents the hierarchical landscape of 'PI3K-Akt Signaling Pathway'. The hierarchical tree allows to click on the pathways with children (black border) and continue the exploration. All nodes are colored by their source (click on the map for the legend) and cross-link to the original pathway page.

Equivalent Pathways
Sub-Pathways

About

ComPath is developed and maintained in an academic capacity by Daniel Domingo-Fernández and Charles Tapley Hoyt at the Fraunhofer SCAI Department of Bioinformatics. This web application relies on data loaded from KEGG, Reactome, and WikiPathways Restful APIs, as well as MSigDB. More information here.