DNA Repair - Pathway Page
Name DNA Repair
Resource Reactome
Genes ACTB POLR2L CDK7 FANCB BLM POLE PNKP PPP5C ERCC6 ASCC1 DDB2 NEIL2 ERCC1 TOPBP1 POLQ UBB UBE2L6 PALB2 RPS27A SUMO1 PIAS4 FANCF EYA4 SLX4 USP45 INO80 EP300 RPA2 DCLRE1A PCLAF NPLOC4 BRCC3 POLK POLN HUS1 DNA2 ACTR5 PCNA MSH2 INO80B FANCC POLH FTO RAD51D TFPT ALKBH5 ISY1 RPA3 CUL4A USP10 CCNH USP1 KAT5 VCP HIST1H2BM SPRTN FANCI RAD23A FANCD2 POLR2B COPS2 HIST1H2BB ATM TDG UVSSA EXO1 SIRT6 ALKBH3 TIPIN REV1 ZBTB32 HIST3H3 ATRIP DTL XPA UBE2N PIAS3 APBB1 POLE2 FANCG TCEA1 RBBP8 HIST1H2BH FANCM ABRAXAS1 BRCA2 SPIDR LIG3 HIST1H2BD RFC2 EYA3 DDB1 RAD51 TDP2 OGG1 NTHL1 EME2 FANCE MGMT SUMO2 POLR2F COPS8 FANCA BRIP1 UBE2I POLR2J UBE2T XAB2 GTF2H2 TDP1 NSD2 POLI EME1 AQR POLD1 ABL1 NFRKB RFC4 RBX1 UBC DCLRE1B MUTYH WDR48 MDC1 MBD4 POLD4 MLH1 ERCC4 FEN1 PMS2 ERCC3 RAD9B FAAP20 RFC5 MAD2L2 UBE2V2 PPP4R2 POLM RCHY1 ADPRHL2 NBN POLR2I ERCC2 HIST1H2BL NHEJ1 PAXIP1 COPS5 COPS7B TIMELESS PRPF19 TP53 UBA7 UBA52 UNG SMARCA5 FAN1 LIG4 CENPS BABAM1 MSH6 MPG HIST1H2BA RAD9A UBE2B CHEK1 FANCL RAD18 XRCC3 ASCC2 POLR2E RAD52 PARP2 USP43 CHD1L MUS81 XRCC6 POLR2A ALKBH2 WRN HMGN1 ELL MCRS1 RUVBL1 POLD3 ACTR8 SMUG1 BRCA1 COPS7A TOP3A USP7 GTF2H3 HIST1H2BJ POLR2D MAPK8 XRCC4 SUMO3 KDM4A RMI2 RHNO1 DCLRE1C PPP4C UIMC1 XRCC1 GEN1 TRIM25 COPS6 BAP1 GPS1 HIST2H2BE XRCC5 HIST1H2BK PARP1 NEIL1 UFD1 RMI1 PIAS1 ISG15 HIST2H4A RAD50 XPC ATR XRCC2 FAAP24 ACTL6A RAD51C APEX1 EYA1 INO80D GTF2H1 HIST3H2BB MSH3 H2BFS CETN2 LIG1 TP53BP1 POLL CDK2 HIST1H2BC RTEL1 PARG ERCC5 GTF2H4 HIST1H2BN EYA2 CHEK2 POLB COPS3 RAD17 CENPX YY1 PPIE POLR2G POLE4 KDM4B INO80E RNF8 SLX1A ZNF830 BAZ1B CUL4B POLE3 INO80C RAD51B ERCC8 CCNA2 GTF2H5 KPNA2 RAD51AP1 RNF168 POLR2C RFC3 RNF111 POLR2H RAD23B BABAM2 MNAT1 PRKDC POLR2K CLSPN HIST1H2BO POLD2 RNF4 FAAP100 BARD1 CCNA1 ASCC3 RAD1 REV3L COPS4 RIF1 RPA1 HERC2 RFC1 H2AFX MRE11
Size 295
Hierarchy Landscape

The following plot represents the hierarchical landscape of 'DNA Repair'. The hierarchical tree allows to click on the pathways with children (black border) and continue the exploration. All nodes are colored by their source (click on the map for the legend) and cross-link to the original pathway page.

Sub-Pathways

About

ComPath is developed and maintained in an academic capacity by Daniel Domingo-Fernández and Charles Tapley Hoyt at the Fraunhofer SCAI Department of Bioinformatics. This web application relies on data loaded from KEGG, Reactome, and WikiPathways Restful APIs, as well as MSigDB. More information here.