Signaling by Interleukins - Pathway Page
Name Signaling by Interleukins
Resource Reactome
Genes POMC BATF SMAD3 IL31RA CDKN1A RAPGEF1 CSF2RA IL12RB2 IL20RB ZEB1 APP SOCS5 PSMB9 NDN RHOU RORA RPS27A HMOX1 MYD88 SAA1 F13A1 ITGB1 CHUK CD86 CCL22 IL27RA IL20 MAPK10 CD4 IL1R2 PSMD9 CXCL1 EBI3 RPLP0 PRTN3 PSMD1 MAP3K7 IL1B IL36RN SEM1 LMNB1 ARF1 CRLF2 SOCS1 S1PR1 HAVCR2 TXLNA RORC LYN STAT5A PSME1 CASP1 ANXA1 IL13RA2 PSMB11 PIK3R1 FOXO1 PSMB10 GATA3 INPPL1 IRS1 IL9R PSMC4 CCR1 IL9 IL23A PIK3CB FN1 PTPN14 PTPN7 NFKB2 MAPK14 PSMB4 ICAM1 LCN2 BRWD1 STXBP2 VCAM1 IL1RL1 S100B LGALS9 MAPKAPK2 BOLA2 SMARCA4 IL7R IL22RA1 PSMC3 IL18BP SOD1 PSMB7 PTPN12 IL17RA CD36 IL13RA1 PELI1 PSMB5 FSCN1 PSME3 IL36G IL11 ALOX15 IL1RAP PSMB2 CCL20 CREB1 HNRNPDL MAPK8 BCL2L1 MAPK3 PSMB3 ITGAM MAP3K3 NFKBIB IRAK4 PSMA5 CRLF1 IL24 VAMP7 UBE2V1 IL17F IL17RB ITGAX CASP3 TGFB1 NOD1 VAMP2 TIMP1 RPS6KA1 IL5 PRKACA TBK1 MAP2K1 TAB2 CRK IL15 PPP2R5D TEC SYK PTK2B IL1A PIM1 PSMD5 P4HB SOS2 VRK3 YWHAZ DUSP4 IL2RA MMP1 CCL19 RAP1B OPRD1 MAPK11 IFNLR1 GAB2 IL3 FBXW11 PTPN9 MAPK1 CCL4 PTPN23 BCL2 RAG2 PELI3 SNRPA1 JUN RPS6KA3 IL25 PSMB1 MAPK9 CNTFR JAK2 IL16 PSMD4 HSPA9 FYN RPS6KA2 MAP2K7 IL23R NOS2 S100A12 IL18 CXCL10 NFKBIA PSMD12 CRKL CSF3 PSMD14 PTPRZ1 SHC1 ALOX5 IL17RC MTAP IL33 IRS2 CCL3L1 GSTO1 RELA IGHE PPIA SOS1 TOLLIP MAP3K8 PTGS2 PSMA7 POU2F1 STAT1 CSF2 PSMA1 DUSP3 IL1R1 AGER RAG1 PPP2CB FOS CCND1 PELI2 MAP2K6 CDC42 LBP MYC TNIP2 ANXA2 CXCL2 IL2RG SOX2 LIF STX4 TNFRSF1A CCR2 PSMD10 UBB PSMD3 PSMF1 STX3 IL19 STX1A TP53 IRAK2 BTRC IL18RAP CCR5 IL27 SNAP25 PSMD8 PIK3R2 PSMD6 IL3RA CSF1R PPP2CA NFKB1 FASLG PSME2 IL18R1 COL1A2 CCL5 RBX1 PTPN4 CSF2RB PSMD13 IRF4 PSMA8 IRAK1 IL22RA2 IL20RA PSMD11 MAOA JAK3 STAT6 TCP1 IL12B RALA OPRM1 IL10RA CA1 GRB2 SKP1 CNTF PDCD4 STAT4 IL6ST TNF ELK1 HMGB1 HCK IL21R CFL1 PSMB8 PSMD2 PPP2R1B IL34 CXCL8 ATF2 IL12A LCK AIP IL15RA VIM IL17C INPP5D CCL3 TALDO1 SDC1 IL1RAPL1 PTPN18 IL31 IKBKB IL13 PSMA3 IL32 UBE2N MAP2K4 SOD2 PSMA4 AKT1 PITPNA HNRNPA2B1 CD80 IL6 IL4R BCL6 IKBKG JAK1 MMP2 MAPKAPK3 MIF MAPK7 CISH ITGB2 RPS6KA5 FPR1 HSP90AA1 TAB1 OSM IL4 HGF DUSP6 HSP90B1 PTAFR MUC1 LIFR IL1RL2 IL36A CTF1 IFNL2 HIST2H3D YES1 PSMA6 IL11RA PPP2R1A SOCS2 UBA52 TSLP IL17RE PTPN20 CANX PIK3CD PSME4 MAP2K3 TAB3 IFNL3 SIGIRR PSMC6 TYK2 IL7 LCP1 CNN2 HNRNPF HIST1H3A PTPN13 DUSP7 IL5RA IL17A JUNB IL1RN IFNG CCL2 SOCS3 CBL PSMC5 MMP3 SERPINB2 NKIRAS1 IGHG4 FCER2 FGF2 MEF2C PTPN5 HIF1A MSN MEF2A IL2 MCL1 VAV1 OSMR FLT3 PSMA2 NOD2 IL37 PTPN11 TRAF6 GSTA2 PIK3CA PSMC2 PTPN2 IL26 IL10 PTPN6 NANOG IFNL1 SQSTM1 RIPK2 CSF1 FLT3LG UBC CCL11 ATF1 IRAK3 STAT2 MMP9 PAK2 VEGFA PSMB6 PSMC1 PSMD7 IL12RB1 CEBPD IL6R STAT5B PIK3R3 CSF3R CUL1 BLNK TWIST1 STAT3 IL21 FOXO3 IGHG1 NKIRAS2 CAPZA1 IL36B IL10RB TNFRSF1B LAMA5 IL1F10 BIRC5 IL22 HSPA8 CLCF1 IL2RB
Size 450
Hierarchy Landscape

The following plot represents the hierarchical landscape of 'Signaling by Interleukins'. The hierarchical tree allows to click on the pathways with children (black border) and continue the exploration. All nodes are colored by their source (click on the map for the legend) and cross-link to the original pathway page.

Super-Pathways

About

ComPath is developed and maintained in an academic capacity by Daniel Domingo-Fernández and Charles Tapley Hoyt at the Fraunhofer SCAI Department of Bioinformatics. This web application relies on data loaded from KEGG, Reactome, and WikiPathways Restful APIs, as well as MSigDB. More information here.