Signaling by Interleukins - Pathway Page
Name Signaling by Interleukins
Resource Reactome
Genes MTAP S1PR1 SMARCA4 PTPN13 UBE2N TGFB1 IFNG PIM1 SOD1 IL17A ALOX5 PSMB4 IL6ST PSMC4 MAPK11 CCR1 STAT5A PSMD5 SQSTM1 SEM1 NFKBIB IL19 PTPN6 MAP2K6 IL12A ALOX15 UBC PRTN3 PPP2CA IFNL3 FCER2 IL27 IL36B IL3 LGALS9 MAOA NKIRAS1 PSMA4 RBX1 COL1A2 PTPN23 TEC IL36G DUSP6 RORC IL2RA TNFRSF1A IL2 IRF4 GAB2 IL22 STAT5B IL10 VEGFA FBXW11 PSMD7 UBB PSME2 VIM RELA FPR1 PTPN5 MAPK8 CCL3L1 IL1RAPL1 NDN FOXO1 PSMD13 PSMD3 IRAK2 MAPK9 CD80 RAPGEF1 OSM ITGAX VCAM1 IFNLR1 PSMD9 JAK3 IL12RB2 IL23R STX1A PELI1 LYN CANX IL33 IRAK1 PSMC5 SOX2 MIF CAPZA1 IL36RN IL13RA2 SMAD3 STAT6 IL31 BCL2L1 TNIP2 HIF1A CREB1 SYK IL37 IL10RB PIK3CB IL16 PPP2CB IL18RAP OPRD1 TIMP1 FOS IL18BP TNF TP53 CSF2RB IL12RB1 CNN2 RAG1 LBP GATA3 CXCL8 MAP2K4 TNFRSF1B BIRC5 IL6R PIK3CD FASLG STX3 BLNK BTRC AKT1 TYK2 PTK2B IL26 IKBKG HSPA9 MAPKAPK3 PSMC3 CNTF PSMD4 STXBP2 SAA1 TBK1 CCL5 MUC1 ELK1 IL11 PSMC1 TXLNA PRKACA IL36A PSMD1 IL15RA RPS6KA3 PELI3 RPS6KA1 ANXA2 POMC MSN JUNB CSF2 FYN NKIRAS2 BCL2 PTGS2 IL17RA ITGB1 CSF1R STAT2 DUSP3 PSMB9 UBE2V1 MAPK3 IL1R2 GRB2 MEF2A IL17RC CLCF1 CDC42 MAPK7 ICAM1 NFKB1 FGF2 CXCL1 CHUK IRAK4 CCL2 PSMB1 PSMD6 IL20RA DUSP7 IL20RB IL22RA2 TSLP SKP1 ZEB1 LIF HNRNPA2B1 MYC NOD2 CASP1 NOD1 HMGB1 IL3RA CA1 UBA52 SOS2 IGHG4 GSTO1 IL1RL1 HNRNPF RPS27A SOCS3 MMP3 IL1RN IKBKB LMNB1 SOD2 PSMB8 IL2RG PSMA6 HGF FLT3 IL11RA IL22RA1 PTPN18 S100B PSMD8 FN1 HMOX1 IL6 IRS2 IL25 PDCD4 F13A1 PSMB10 CDKN1A BATF CD86 IL34 MAPKAPK2 RAP1B CCL4 IL1F10 SOS1 IL12B MAP2K7 PSMA8 TAB3 TWIST1 MMP1 IL17RB CCL11 PTPN7 BRWD1 CXCL10 CBL CTF1 SOCS2 VRK3 MAPK14 PSMB2 SNRPA1 STAT1 CASP3 RPS6KA5 IL21R PTPN11 CD36 NOS2 ITGB2 PTPN4 SERPINB2 PIK3R3 IFNL1 CRLF2 CSF3R S100A12 PTPN9 JAK2 TAB1 JUN LCP1 CCL20 PSMB3 MYD88 CD4 IL7 HSP90AA1 IL4R PTPN2 CSF1 LCK PITPNA IL20 IL15 MEF2C SOCS1 IL32 CNTFR PPP2R5D EBI3 TALDO1 IRS1 YES1 IL17RE MCL1 ATF2 CCL22 MAP2K3 PPP2R1A CCR5 IL21 IL1RAP CFL1 PIK3CA BOLA2 IL27RA PSME4 IL23A SIGIRR STAT3 AIP PSMB5 IL1RL2 IL7R MAP3K3 HAVCR2 ARF1 IL4 VAV1 IL17F LIFR TCP1 IL2RB PSMF1 PIK3R2 PPP2R1B CRK PSMB7 CCR2 APP MMP9 IL17C HIST1H3A IGHG1 FLT3LG SHC1 LAMA5 INPPL1 PSMB11 PSMA3 GSTA2 VAMP7 IL18 PELI2 CRKL ANXA1 MAP2K1 PTPN12 P4HB POU2F1 FSCN1 IL9R IL5RA DUSP4 RALA CEBPD LCN2 IL13RA1 CCND1 OPRM1 PSMD2 HIST2H3D IL1A JAK1 ATF1 AGER IL13 MMP2 STAT4 IL24 PTPRZ1 PSMD14 IFNL2 MAPK10 PSMA2 RAG2 RORA MAP3K8 FOXO3 PSMB6 ITGAM IL9 TAB2 OSMR IL18R1 NFKBIA PIK3R1 IL1R1 PTPN20 PSME1 SOCS5 CUL1 PAK2 PSMD11 CSF3 YWHAZ VAMP2 TRAF6 BCL6 NANOG IL31RA CSF2RA CRLF1 IL5 PSMA1 PSMA7 PSMC6 IGHE MAP3K7 RPS6KA2 PSME3 RIPK2 CXCL2 SDC1 CISH STX4 PSMA5 IRAK3 IL1B PTAFR PSMD10 CCL3 IL10RA NFKB2 CCL19 INPP5D PTPN14 HSP90B1 SNAP25 RPLP0 PSMC2 RHOU HNRNPDL PSMD12 MAPK1 HCK TOLLIP HSPA8 PPIA
Size 450
Hierarchy Landscape

The following plot represents the hierarchical landscape of 'Signaling by Interleukins'. The hierarchical tree allows to click on the pathways with children (black border) and continue the exploration. All nodes are colored by their source (click on the map for the legend) and cross-link to the original pathway page.

Super-Pathways
Sub-Pathways

About

ComPath is developed and maintained in an academic capacity by Daniel Domingo-Fernández and Charles Tapley Hoyt at the Fraunhofer SCAI Department of Bioinformatics. This web application relies on data loaded from KEGG, Reactome, and WikiPathways Restful APIs, as well as MSigDB. More information here.