Signaling by Interleukins - Pathway Page
Name Signaling by Interleukins
Resource Reactome
Genes IL23R MMP9 IL18R1 FOXO3 IL23A RPLP0 IL1R2 CSF1 CCL2 PSMC2 SOS2 IFNL1 PIK3R1 CEBPD ALOX5 PTPN7 FASLG CCR2 IL36G MEF2C RPS6KA3 IL36RN IL7R TSLP STAT3 UBB TAB3 CNTFR CCL22 VEGFA NFKB1 CCL19 PSMA6 S1PR1 P4HB MAP2K1 IL11 MAOA IL3 IL7 LGALS9 IL17C TBK1 MAP2K3 TAB2 HIST2H3D CD4 HIF1A PSME2 HAVCR2 MAPK14 PSMD9 NFKB2 ALOX15 COL1A2 MMP1 SOD1 FBXW11 SKP1 IRAK2 HSP90B1 PSME3 CTF1 IL1RN BCL2L1 ICAM1 IRS2 BLNK PSMD5 POU2F1 ATF2 INPP5D IL12B PPIA IL15 PTK2B TWIST1 IL10 STXBP2 MIF HSP90AA1 TRAF6 CCR5 APP IL22RA2 IL13RA1 OSMR RAPGEF1 MAPK7 JAK3 CCL5 IL2RG PTPN6 IL10RB MMP2 ARF1 RHOU IL11RA PSMD7 SOD2 NDN LCP1 NOD2 IL36B TXLNA VAMP7 IL19 PPP2R1B PTGS2 ELK1 CASP1 CCL11 IL1F10 CHUK PSMD13 UBE2V1 PSMB11 CAPZA1 IL17RA IL2RB ITGB2 VAMP2 AGER RPS6KA2 IL27RA PSMB3 MTAP RPS27A IL27 PSMB1 LCK IKBKB PIK3R3 RELA SDC1 JAK1 IL17F RBX1 SEM1 IL5 MAPKAPK2 HSPA9 OPRD1 PTPN13 CXCL1 VCAM1 PTAFR DUSP6 IL16 CXCL8 PTPN11 MYC UBE2N IL20RB CCL3L1 YES1 HCK SOCS1 CSF2 CSF1R IL1RAPL1 CSF3R VRK3 PSMB6 MAPK3 PSMA8 CCL3 IL31RA PSME1 CSF2RA PTPN23 TP53 CCR1 SNRPA1 IL1B IL26 BTRC PSMD8 MAP3K7 NKIRAS2 LBP PSMF1 STAT2 MCL1 IL6 IL13RA2 PPP2R5D LIFR PSMD2 DUSP7 IL1A NFKBIB IL21R IGHG1 JUN CD86 RORC IL22 CFL1 IL18 FN1 PSME4 MAPK9 STAT1 PSMD12 IL33 MAPK1 IL3RA IL24 PSMB4 IL12RB1 IL18BP PTPN14 FYN PTPN18 PSMA3 ITGAX PTPRZ1 PSMB8 UBA52 TNIP2 PIK3CD IGHE VIM TYK2 PSMD6 PSMB2 CLCF1 ANXA1 IL4R PRTN3 RIPK2 IL21 PRKACA BATF LMNB1 PIK3R2 CUL1 TNF IRAK1 PDCD4 HSPA8 HIST1H3A IL34 MAP2K4 GSTO1 PSMD3 ANXA2 PAK2 TIMP1 PSMB9 S100A12 TOLLIP PSMC5 TGFB1 PSMA7 CCND1 PTPN4 MYD88 CA1 IL5RA LCN2 PSMB5 ZEB1 PSMA2 HNRNPA2B1 CSF3 IL37 BRWD1 FGF2 IRAK3 SOCS3 MAPK10 IL9R TALDO1 IL32 IL22RA1 OPRM1 IL1R1 JUNB VAV1 SIGIRR PIK3CA MAP3K8 RPS6KA5 IL6ST ATF1 OSM SOCS5 LAMA5 BCL6 CRLF2 POMC CNN2 DUSP3 CCL20 PSMC4 BIRC5 MAPK8 FLT3 FLT3LG CXCL10 IL25 IFNL3 CD36 BCL2 SMAD3 CREB1 HGF PTPN5 MAP3K3 MMP3 SOX2 STX4 STAT4 TNFRSF1B CSF2RB FSCN1 PSMD11 NANOG SMARCA4 FPR1 GAB2 FCER2 IL12RB2 PTPN12 MUC1 CCL4 SHC1 MAP2K7 PSMB10 IFNLR1 CXCL2 LYN SQSTM1 RALA IL15RA IL36A F13A1 PPP2R1A DUSP4 PSMC3 PSMD10 LIF SOCS2 IL4 YWHAZ IL31 RORA CASP3 STAT5B STAT6 JAK2 PSMA4 STAT5A INPPL1 IL2 CRLF1 TAB1 PTPN9 IL13 CDKN1A S100B PSMD14 RAG1 MSN NFKBIA IRAK4 IL1RL1 HNRNPDL GRB2 TEC IL20 CISH HNRNPF PIK3CB BOLA2 SERPINB2 PITPNA TNFRSF1A PIM1 FOS STX3 PSMD1 IGHG4 STX1A IFNL2 PSMC1 IRF4 PSMC6 MEF2A EBI3 CDC42 RPS6KA1 MAPK11 IKBKG MAP2K6 GATA3 HMGB1 IL18RAP PSMA1 PPP2CA IL2RA HMOX1 IL17A CANX UBC IL17RE ITGB1 IL10RA PELI1 PTPN20 IL20RA CNTF SNAP25 CBL TCP1 GSTA2 PSMD4 NKIRAS1 ITGAM IL12A CRKL NOD1 NOS2 PPP2CB FOXO1 SYK IL6R IRS1 IL9 CD80 AIP IFNG SOS1 SAA1 IL17RC IL1RAP RAP1B IL1RL2 PELI2 IL17RB AKT1 CRK PTPN2 PSMB7 RAG2 PELI3 PSMA5 MAPKAPK3
Size 450
Hierarchy Landscape

The following plot represents the hierarchical landscape of 'Signaling by Interleukins'. The hierarchical tree allows to click on the pathways with children (black border) and continue the exploration. All nodes are colored by their source (click on the map for the legend) and cross-link to the original pathway page.

Super-Pathways
Sub-Pathways

About

ComPath is developed and maintained in an academic capacity by Daniel Domingo-Fernández and Charles Tapley Hoyt at the Fraunhofer SCAI Department of Bioinformatics. This web application relies on data loaded from KEGG, Reactome, and WikiPathways Restful APIs, as well as MSigDB. More information here.