Signaling by Interleukins - Pathway Page
Name Signaling by Interleukins
Resource Reactome
Genes IGHG1 STAT6 HMGB1 CSF1R IL26 IRAK1 PSMC1 SOX2 IKBKG HSPA8 MAP3K8 PTPN9 PSMA2 IL17RA SNAP25 IL17RC CXCL10 PSMB5 PSMD11 UBE2N PRTN3 IL15RA NKIRAS2 HCK TOLLIP MAPK8 MAP2K3 CLCF1 IL2RB HNRNPF PPP2R1A DUSP6 IFNG SQSTM1 VAV1 PSMB11 TNF HSP90AA1 VEGFA CNTF IL9R IL36G VRK3 JAK2 IL16 IL37 IL5RA RAG2 TEC PSMB8 CD4 CCL22 LIFR PELI2 NFKB1 MIF IL1R2 IL1RL1 BOLA2 PDCD4 CHUK IRAK2 CNTFR IRAK3 CSF3R MAPK14 SEM1 IL27 LYN TWIST1 IL36RN DUSP7 ANXA1 IRS1 OPRM1 IFNL3 PELI1 TP53 PTPN20 STAT5B IL34 IL23A OSMR FN1 F13A1 IKBKB RHOU IL27RA PSMB2 PIK3R3 LAMA5 PSMC5 IRF4 ITGB2 IL20RA INPPL1 HIST1H3A IL13RA1 CCL11 ZEB1 S100B NANOG PSMA3 MAP2K4 CEBPD NFKBIA PTK2B PSMD10 LBP MMP9 MCL1 NFKBIB PPP2CA FASLG PELI3 PIM1 JAK1 IL4R TSLP PIK3R1 CCL2 IL17RE BATF PSMA1 HNRNPA2B1 SDC1 PTPN2 PSMD6 IL24 AKT1 IL36B IL17C CCL3 ALOX5 PSMB9 MAP2K6 MYD88 POMC IL7R SOD2 PITPNA IL17A TAB3 PTPN6 PTPN12 YES1 PSMB7 HSP90B1 CCND1 CSF1 LCN2 IL1A IL11 CXCL1 LCK IL1RAPL1 RPS6KA2 TRAF6 JUNB UBE2V1 RPS27A CSF2RA CDKN1A FLT3LG TYK2 TNFRSF1A IL20RB MAPKAPK2 TCP1 CANX SNRPA1 SKP1 IL13 MAPK9 IL9 RAP1B IL6ST ALOX15 PSMC2 CNN2 IL2RA PSMB6 CCL3L1 PSMD3 HGF P4HB UBB CRLF2 SIGIRR TNFRSF1B IL22RA1 PAK2 OPRD1 MTAP BCL2 PPP2R1B PIK3CB STAT3 IL1R1 FSCN1 INPP5D ITGAM ELK1 IL17RB CA1 FGF2 IGHE RELA IL10RB IL3RA MEF2C CD86 MUC1 MAPK1 IL4 PSMC6 IL1RL2 MAPKAPK3 IL1B BIRC5 IL18BP CUL1 PPP2CB MAP2K7 TBK1 SMARCA4 JAK3 PSMB3 STAT1 RPS6KA3 GSTA2 CCR5 PSMD5 PTPN18 PIK3CD IL12B TXLNA STAT4 PTPN5 PSME2 STAT2 IL33 UBC RALA PSMA7 RPS6KA5 CD80 GATA3 LGALS9 MAPK3 FYN PSMA5 IL18RAP IL13RA2 TGFB1 VIM SYK IL12RB1 ANXA2 PSMD7 IL1RN IL3 PSMB1 PSMA4 IL22 CCL20 CRK RAPGEF1 PIK3R2 TALDO1 NDN PTGS2 RBX1 UBA52 FOXO1 MMP1 NOD2 SOS2 IL1RAP IFNL1 HAVCR2 CCL19 MMP2 IGHG4 FBXW11 FOXO3 PRKACA IL21 TIMP1 BCL6 IL6R HSPA9 TAB1 RIPK2 PTAFR CFL1 SHC1 CDC42 IL23R PSMD9 IL12A ICAM1 IL7 BRWD1 MYC RPS6KA1 PPIA SOD1 FOS LIF IL1F10 STX3 CCR1 AGER MAP3K7 IL10 APP FPR1 STX4 PSME4 IFNL2 SOCS5 MAPK10 CBL IL31RA IL18 IL18R1 IL2RG YWHAZ CAPZA1 CSF3 EBI3 SOCS1 GRB2 MAPK11 SAA1 TAB2 IL21R SMAD3 POU2F1 IL15 MAP2K1 IL5 STX1A IL17F PSMB10 ITGAX IL6 IRAK4 MSN PPP2R5D STXBP2 CASP1 OSM MAPK7 PSMF1 PSMD4 AIP VCAM1 COL1A2 PTPRZ1 HNRNPDL S100A12 IRS2 PSME1 MEF2A CRKL NFKB2 IL12RB2 LMNB1 NOS2 SERPINB2 TNIP2 PTPN13 CXCL2 PTPN7 IL19 CCL5 STAT5A NOD1 ATF2 PTPN14 PTPN23 IL10RA HMOX1 HIF1A FCER2 IL36A SOCS2 CCL4 CCR2 GSTO1 ITGB1 RAG1 VAMP7 BCL2L1 IFNLR1 CASP3 HIST2H3D PSMA8 RORA PSMD1 ARF1 PSMD13 PSMD2 JUN PSMC3 DUSP3 CRLF1 DUSP4 GAB2 IL32 CD36 ATF1 IL31 CXCL8 CSF2RB IL22RA2 PIK3CA MAP3K3 SOS1 CREB1 MMP3 PSMC4 SOCS3 S1PR1 IL20 NKIRAS1 LCP1 FLT3 CSF2 BTRC PSMB4 PSMA6 VAMP2 IL2 PTPN4 BLNK IL25 CTF1 RORC IL11RA CISH RPLP0 PSMD8 PSME3 PSMD12 PSMD14 MAOA PTPN11
Size 450
Hierarchy Landscape

The following plot represents the hierarchical landscape of 'Signaling by Interleukins'. The hierarchical tree allows to click on the pathways with children (black border) and continue the exploration. All nodes are colored by their source (click on the map for the legend) and cross-link to the original pathway page.

Super-Pathways
Sub-Pathways

About

ComPath is developed and maintained in an academic capacity by Daniel Domingo-Fernández and Charles Tapley Hoyt at the Fraunhofer SCAI Department of Bioinformatics. This web application relies on data loaded from KEGG, Reactome, and WikiPathways Restful APIs, as well as MSigDB. More information here.