Toll Like Receptor 4 (TLR4) Cascade - Pathway Page
Name Toll Like Receptor 4 (TLR4) Cascade
Resource Reactome
Genes MAP2K7 LY96 NOD2 PPP2R1B ELK1 BIRC3 DNM3 PPP2R1A DUSP4 CHUK UBE2V1 RIPK2 CASP8 CUL1 DNM2 MEF2C IRAK1 ITGB2 AGER RPS6KA3 RPS6KA2 TAB1 S100B RPS27A UBB MAP2K4 TAB3 CD180 NFKBIA IKBKB RELA NFKB1 IRAK4 MAP3K1 MAP2K1 MAPKAPK2 ECSIT DNM1 TICAM2 DUSP6 S100A12 TANK TLR4 TLR6 PTPN11 CD14 PTPN4 UBE2N TBK1 MYD88 FOS SOCS1 MAP2K3 TAB2 LY86 IRF3 MEF2A SFTPD VRK3 RIPK1 RPS6KA1 IRAK3 MAPK11 IKBKG MAP2K6 HMGB1 MAPK14 MAPK10 PLCG2 IRF7 PPP2CA MAPK3 NFKB2 SARM1 FADD FBXW11 UBC SIGIRR SKP1 IRAK2 TIRAP MAP3K8 RPS6KA5 TLR1 BTRC PELI1 ATF1 MAP3K7 NKIRAS2 LBP PPP2R5D ATF2 DUSP3 BIRC2 DUSP7 NKIRAS1 ITGAM MAPK8 NFKBIB NOD1 JUN TRAF3 PPP2CB SFTPA1 UBE2D3 BPI TRAF6 CD36 MAPK9 TLR3 APP TLR2 SAA1 MAPK1 CREB1 IKBKE UBE2D1 BTK PELI2 MAPK7 RIPK3 UBA52 TICAM1 PELI3 SFTPA2 UBE2D2 TNIP2 MAPKAPK3
Size 128
Hierarchy Landscape

The following plot represents the hierarchical landscape of 'Toll Like Receptor 4 (TLR4) Cascade'. The hierarchical tree allows to click on the pathways with children (black border) and continue the exploration. All nodes are colored by their source (click on the map for the legend) and cross-link to the original pathway page.

Super-Pathways

About

ComPath is developed and maintained in an academic capacity by Daniel Domingo-Fernández and Charles Tapley Hoyt at the Fraunhofer SCAI Department of Bioinformatics. This web application relies on data loaded from KEGG, Reactome, and WikiPathways Restful APIs, as well as MSigDB. More information here.