Signal Transduction - Pathway Page
Name Signal Transduction
Resource Reactome
Genes BEX3 PMCH DRD2 CASP2 OPRL1 RLN3 STAM FRAT1 LAMB3 YWHAB RGS9 DLL1 KCTD6 CSNK2B ARHGAP8 TAS2R19 RALB OR11H7 CCL25 ACTN2 PSMA2 GPR18 NDE1 SP1 ARHGEF35 PSMB5 OR2C1 RASGRP3 RNF111 BMI1 MAPK8 AXIN1 CTNND1 RAMP3 FGF22 OR6Y1 YBX1 CDC25C OR56A4 MYLK PRKCA DTX2 FZD7 OR12D3 OR6F1 PPP2R5E KIF2A COL5A2 LTB4R2 PHC2 ABHD6 VRK3 CCR3 PRKCD GNB4 JAK2 TUBB6 PDYN DUSP16 LAMC3 FRS3 NTS PLPPR1 DVL2 TACR2 TUBA1C TEC SHARPIN SCUBE2 GRM8 PARD6A ATP2A2 GPR4 LPAR1 NFKB1 ARHGEF5 PLEKHG2 ROPN1 OR4D5 PLXNB1 OR5F1 GPC4 DOCK7 RXRB MAD2L1 STARD13 RGS1 OR13J1 SPTAN1 OR4D2 DRD4 OR4F4 C3 DOK1 CCNE1 AP2B1 ARHGAP29 TNKS OR10H3 NOS3 OR1S1 OR10D4P FGF18 TGIF1 MAG LYN BUB1 MARK3 IRS1 OPRM1 OR2T5 NPFF KISS1 CCL27 PTGER3 PNOC TGIF2 SMAD2 ARAF ITCH KIF14 MAP2K2 FKBP5 TRHR WWTR1 POLR2B OR2K2 CHEK1 TAS2R42 CDC14B GRM4 NOTCH2 OR2A7 GHRH MAML1 OR51S1 OR10Q1 OR6T1 OR51F1 SPOPL PDE2A CHRM5 NPY5R HIST1H3A EGF OR10G3 SKI OR1F1 GPR132 S100B OR2T4 FGFBP1 TBXA2R RBFOX2 OR51A4 GNA11 LAMA4 DNM1 LRP6 OR52K2 TAAR9 OR6Q1 ARTN OR4M1 OR5D13 ARHGAP28 RALGDS ADCYAP1R1 SYNGAP1 NOXA1 JAG1 PPP2CA PENK OR5B2 FASLG TUBAL3 YY1 IFT140 POLR2G TRAF1 LRP8 OR51V1 TAS2R9 RAC1 BUB3 CCR8 PIK3R1 OR51B6 BCL9 TGFA RBL1 GPR143 DAB2IP OR5AU1 POLR2E FGFR1 ATP6V1G2 XCR1 LINGO1 PTPN2 PSMD6 OR8B8 TLE1 ARAP1 FST MAP3K11 OR11H1 CCL4L1 IKZF1 APOB MTNR1A PDE4B GGA3 TAS2R45 AKR1C1 HIST1H2BK ATP6V1C2 PPID TAB3 RRAGB PTPN6 ACTG1 ERLEC1 PREX2 YES1 PDGFC RAB4A PSMB7 RHOV LIMK1 CCND1 TAC1 RXFP4 OR8K1 OR1D5 DKK1 WNT5B TCIRG1 AMOTL2 OR5P2 OR52A4P LCK KLC1 OR4F17 USF1 HIST3H2BB RAB6A USP15 HIST1H2BA RGS7 NCK1 GPR55 TRAF6 JUNB SSTR3 SH2B3 ATP2A3 OR5B3 PAK3 AGTR2 MET CSF2RA RBP3 HES5 FOSB SDR9C7 TNKS2 ARHGAP11A FADD GLP2R TAAR3P OR1J2 TAS2R43 ADRA2A DUSP2 OR9A1P DYNC1LI2 IGF1R KANK1 DHRS9 NUP85 ECE2 SEL1L GNG10 RTP4 OR5G3 PLCB2 LIMK2 FNTB NR2E1 PTGIR RHPN2 SSTR2 EVC2 UBB PLB1 OR6M1 LHB PDK3 OR6C74 PIK3CB OR1I1 KISS1R CD28 ATP6V0E2 OR4X1 TRRAP OR6N2 TGFBR2 FSTL3 ESR2 RIT1 NMT2 ARHGEF6 OPN4 CAMK4 FGF2 CXCL16 GAS8 RELA UBE2D1 AKR1B10 OR2M7 OR2C3 FURIN RCC2 CENPP VCL PKN3 FBXW7 KSR2 CCNT2 CDK5R1 NOTCH3 OR1F12 ROR1 MAPK1 EPS15 PPP1R12A UCN3 TAS2R7 MLST8 KAT5 MAPKAPK3 OR1D2 OS9 HIST1H2BJ TACR3 CUL1 DAAM1 ARHGAP31 OR52E1 RASAL2 OR2W3 SMARCA4 WNT3 CENPT ARHGEF1 RPS6KA3 OR51I2 MKNK1 ADCY5 AURKB PTPN18 HTR1E CMKLR1 TAC3 P2RY2 BRAP MAPKAP1 GPR25 PSME2 NTRK2 OR2T11 PSEN1 BCL9L TNFRSF10A OR2T6 HIST1H2BM AGT AKR1C4 TAAR6 UBC CER1 RALA OR10A4 UCN2 HTR1B PAK1 FKBP4 OR2L3 BOC WWC1 EDN3 TUBB4B MAPK3 LGR6 PGR E2F4 CCL1 C3AR1 PRKAG2 DEPDC1B OR52E8 POFUT1 SYK ACVR1C TRIB3 PSMD7 SNAI2 DIAPH2 TNFSF10 RDH16 TAX1BP3 NOTUM DRAP1 CCL20 ATP6V1A CRK CENPF KAT2A CYP26C1 TUBA8 OR2AT4 PIK3R6 MCF2 IQGAP2 ROR2 DGKE RBX1 OR1N1 YWHAE SOS2 IL1RAP TCF7L2 ITSN1 PDE1B GPR31 CCL19 KDM1A ABR CNGA1 EDNRA OR9A2 CSNK1A1 FGFR2 FOXO3 HIST2H2AC DSN1 CBFB OR2I1P CPT1A NDC80 CTNNBIP1 PTH2R OR10C1 RGS9BP SHC1 ACTR3 PPY CDK5 GABBR2 FSHB RACK1 CNKSR1 OR5M8 TLE3 ZW10 COL4A1 OR4D11 MYC RPS6KA1 PDHA1 DISP2 CASP9 NOTCH4 KRAS NRIP1 PLPPR5 OR51E1 DHH OR4K17 OR4F21 ERBB3 GRK2 WNT7A PIK3R4 ST3GAL6 OR1A1 PTCRA FZD2 OR8B2 OR4F6 RAPGEF2 GNB3 ADORA3 GREB1 PPP1R12B OR4K13 ARHGAP42 C5 E2F3 OR9G4 MTMR4 GPR161 OR5K4 OR56A3 KREMEN2 SOX3 EIF4B NPY1R GRIN2A SLC24A1 ACKR3 EDNRB GRB2 WASF2 HNRNPH1 PDE4C THBS4 GCG SMAD3 H2BFS FGD2 OR2AE1 LRP1 WNT16 IL5 BDNF CCKAR COL4A5 OR52D1 LRP10 IRAK4 NUP160 STRA6 AVPR2 PRMT1 GNRH1 HDAC4 GOPC ZFYVE16 FGF9 LAMC1 KDM4B SPC25 TNRC6A CALM1 CCND3 EGFR GRK3 MAPK13 UTS2R SCAI GNGT1 ADGRE5 OR7D2 WNT7B AR BIRC2 OR2A12 DNM3 ARHGAP18 FFAR3 OR8U8 RPE65 PIP4K2C OR51A2 PCP2 AVP NPFFR2 OR8U9 FPR3 MIS12 OR4C46 PDE3A GPHA2 ABI2 TUBB2A PARP1 HIF1A TAS2R50 KEL AXL ARHGDIA OR2AG1 CASP8 RAC2 ADRB3 DDX5 CCR2 PPP1CC DGKB FFAR1 ITGB1 LATS1 MTA1 ARHGAP40 TAS2R41 PSMA8 ARHGAP25 PDE6A GPSM2 JUN PSMC3 SOCS6 ARHGEF16 IFT122 BAX ESR1 RHEB OR2G6 CDC42EP3 OR13G1 B9D2 DUSP3 CNR2 TNRC6B USP9X FGD3 FOXH1 HIST2H2BE PLCG1 GAB2 OR4A4P GRK7 HDAC1 ZWILCH CHD3 F2RL2 OR4D6 SOX6 RLBP1 KIF2C MOB1B ARHGAP27 WASF3 PDHX HCRTR1 RGS3 OR6C76 LRAT OPN1SW OR2A5 TAS2R20 OR7D4 MAPRE1 FNTA CLASP2 HIST1H2BL ZFYVE9 CSNK2A1 PRICKLE1 SDC2 OR8I2 INSR RHPN1 FABP7 NUP107 FRAT2 OR4A15 PTPRK KL OXT OR5H1 BAD GFRA2 NEURL1B RANBP10 OR7A17 RHOB ARF6 GDI2 PRKAR2A COL9A2 NCKAP1L OR2Z1 FGD4 RHOF ACVR1B FES ANGPT1 WAS AGTR1 HRH1 RGS20 COL11A1 OR7A2P RSPO3 PTGFR RBBP7 IRAK1 SOX7 GALR2 EP300 WASL TBP OR13C8 ZWINT LAMTOR4 PRKAR1B LIN7B PARD3 PPARG MST1 OR10A7 WNT1 GNG12 CENPH CX3CL1 NRP2 CXCL10 GRM5 GNAQ PSMD11 CSNK2A2 TRPC3 PXN GNG3 OR5AK2 OR52N2 HIST2H2AA3 AP2M1 HNRNPF SNX3 TFF1 OR8K5 OR5M10 NEDD4 MTOR AKT2 PROK2 ULK3 CENPL OR11H2 SPTBN5 OR51G2 OR1E1 MC2R PDE1A OR2A14 NCKAP1 IL5RA PSMB8 OR52K1 RARG APLN SSTR5 CXCR6 GRP OR8A1 H2AFJ OR2G2 IL1RL1 RASGRP1 REEP6 OR6P1 NSL1 ACKR4 APOC2 MAD1L1 DVL1 NPS LEO1 SPRED3 NRG3 TUBB8 NCF1 ATP6V0B CCR6 OR1D4 OR5H14 SMAD6 CITED1 CLTA HBEGF OR7C1 OR1E3 GPR39 OR10J5 ANXA1 MCHR1 CBX8 OR2J1 OR51G1 RDH13 RGS2 P2RY11 EZH2 HCAR3 OR51J1 TP53 TAS2R4 RTN4R PDE10A CXXC4 KLC4 RRAGA GRK5 PRLHR PPP3R1 CDC20 RHOU TGFBR1 OR4L1 GNG5 KDM4C PSMC5 TIAM1 AGO4 RHOBTB2 TAS2R5 OR51E2 ACVR2A MAPK6 PROKR1 OR13A1 CRABP1 OR2T7 MC3R PDHB LPAR3 OR5AR1 MLN NFKBIA OR56A1 OR6J1 RAPGEF3 RANBP9 LPAR6 GPNMB TJP1 ADORA2A PMF1 NRP1 PRKCE SMPD2 TAGAP RALBP1 DGKI ARHGAP20 LAMTOR3 MC5R OR8J1 TACC3 BRAF PLK1 JAK1 PTPRO OR52H1 FZD4 AHCTF1 DYNC1H1 CSNK1G2 COL4A2 OR52E2 PSMA1 VAV3 CDON CDH1 PSMB9 BDKRB2 WIF1 DOCK3 HDAC8 HTR1A GSK3B MTA2 OR52N5 MYD88 EIF4EBP1 OMG CDKN2B FLT1 RTKN ATP6V0D2 CENPI OFD1 PRKG1 RTP2 S1PR5 TUBB3 ARHGAP6 OR51T1 RGS14 CBX6 ATP6V1B2 RPS6KB2 BDKRB1 CRH PLPPR4 POLR2A RUNX3 HDAC7 GMIP OR2T8 OR1L4 SAV1 P2RY1 NMUR1 HHAT OPN5 KHDRBS3 RPS6KB1 DNAL4 HDAC6 CDK1 PTPN3 ARHGEF38 STRADA S1PR4 PLXND1 RPS6KA2 FGF6 GPHB5 GALR1 UBE2M RPS27A OR1G1 NCOA2 DRD3 CDKN1A OR1L3 OR5A1 FGFR4 RANGAP1 STUB1 TYK2 VANGL2 CTBP1 DRD5 GPR45 OR6A2 ARHGAP12 ARPC5 GABBR1 SH3GL3 MECOM CTSD FZD6 ITGB3 BCAR1 PPP3CA ADAM10 ITPR1 RAP1B IL6ST TSHB OR52N4 VEGFD PSMB6 PROKR2 DVL3 GRB10 NCKIPSD HGF SPP1 OR6S1 PAK2 PPP2R1B PTK2 ARPC2 CSK ADRA1D RNF43 OR6B3 OR4D10 OR5T3 CCR10 OR5B12 LFNG OR5L2 OR8G1 OR8S1 ABHD12 OR8B12 SRGAP2 AVPR1A ELF3 SPTBN2 USP34 DGKQ CNTN1 GNRHR2 NEDD8 HTR6 IL3RA OR6C3 INHBA MEF2C NUMB COL6A3 HDAC9 ATP6V0A1 TAS2R39 CYBB CD86 YAP1 OR2B2 FMNL2 ESRP2 GPIHBP1 COL3A1 ARHGEF17 KLB REEP2 RCVRN OTUD7B RASGRF2 PRR5 E2F1 OR13C4 RASGRF1 COL5A3 GNAS OR2T2 RDH11 CCK ADCY6 OR4X2 ERBB4 PPP1CA BMP10 PSMD5 COL5A1 PIK3CD GTF2F2 IER3 PTK6 DUSP1 PMEPA1 CENPO PDE8B OR11G2 LHCGR OR5M9 HNRNPM NUP43 NMB NCBP2 MAML2 FAM13A CSN2 PSMA7 MTNR1B RARB OR10G4 OR8H1 STRADB TMED2 OR1J1 GATA3 KBTBD7 WNT2 PTGER1 PPP5C COL1A1 OR4C15 P2RY14 TAS2R10 PSMA5 CCR9 OR51B4 NRG4 HRAS TERT PTGES3 HEY2 HDAC3 ATP6V0D1 GUCY2D PFN2 GRIN1 PSMB1 RBBP5 RDH14 GPC3 RGS17 SMAD1 NOX1 CXCL5 SPRY1 MUC20 PIK3R2 ITGAV CDC42EP2 APLNR FSTL1 SFRP2 TAAR8 POLR2D OR52B6 ARHGEF9 HCAR1 WNT8A CCNK NF1 GZMB KLK2 CDK8 ADAM17 SRGAP3 RAC3 POLR2J HTR2A SRY PTPN1 OR8J2 PDK1 DKK4 OXTR OR10J4 OR1E2 REEP4 GFRA1 S1PR3 TNFAIP3 OR10A2 PRKAG3 OR1M1 EVC BCL2L11 PLG RGR BCO2 SMC1A MFNG CDC42 OR8D4 APOA2 CYSLTR1 TSC1 RHOQ OR10A5 PSMD9 DGKG LATS2 SPTA1 PRKACB OR6C4 DLG4 OR52Z1 GDNF SUFU NEDD4L GPR32 RBP1 ATP6V1G3 CCKBR PBX1 MAP3K7 APP OR13C3 OR51A7 TAS2R40 USP21 OR5AP2 NUF2 SH2B1 GRB7 RRAGC PSME4 NDEL1 ACTA2 CENPN PRKAB1 CENPU CNR1 PPP1R1B YWHAZ OXER1 FGF8 MAGED1 LRP5 CUL5 OR11L1 VIP BMP2 CDC73 OR6V1 SHH CRHBP OR10G6 KPNA2 RAP1A TRIO OR2L8 WDR35 CENPQ CXCR3 HTR4 NCOA1 ARHGAP4 OR4C3 POU2F1 PRKAB2 LAMB1 MAP2K1 PSMB10 OR5L1 OR1A2 VPS35 EIF4E TAS2R60 ST3GAL4 OR13C2 OR10J1 INSL5 ADCY2 PSMD4 UTS2B ARHGEF40 CNGB1 OR2W1 DHRS4 FGF4 MEN1 ARHGDIG PROK1 CENPE CYFIP1 RHO PRLH APOM CBY1 SOX17 OR6C2 THBS2 ZNRF3 GRM1 HEBP1 UCN SMURF2 PAFAH1B1 NPSR1 SFPQ GUCA1B OR4M2 CALCRL SMAD5 MATK OR11A1 NAPEPLD FRS2 OR2M2 OR4Q3 IQGAP1 HSD17B1 SCMH1 E2F5 AKT3 PIK3C3 CREBBP SPTB ARHGAP36 RING1 OR4A16 SEPT7 OR4C6 NLK FGF16 OR3A2 OR3A1 IGF2 RAG1 NET1 TAS2R14 OR8G5 CLTC PTPRJ ADRA1A PSMD1 RNF2 OR7G3 IAPP OR1P1 OR51B5 CCL21 NRG2 GNAL OR4K1 ADM KIT C5AR2 ARHGAP11B HTR5A DYNC1I1 EPN1 PPM1A DGKH GNAT1 PEBP1 RGSL1 RDH8 RUNX1 DYNC1LI1 CXCL8 HIST1H2BB GPR84 NPY AVPR1B TAS2R1 DIAPH1 COL6A5 OR52B2 CARM1 AKR1C3 ACVRL1 GLI2 MOB1A OR2M5 CAMK2A PHLPP1 GPR37L1 S1PR1 BMPR1B THEM4 USP7 KLC3 FER RHOA CDK4 BIRC3 BTRC PIK3CG RTP5 ARHGAP15 SNAI1 TAS2R8 IL2 POLR2I ALDH1A1 ADORA2B OR52I2 HDAC5 PSMD12 JAG2 CCL13 SPRED2 GNA12 BTC NPY2R HSD17B6 GNB1 RPS6 SKIL GRK6 INTU POLR2L COL2A1 PSMC1 ASH2L SOX4 ARHGEF15 IKBKG GPC6 APOA1 PPP2R5B OR7E24 ECE1 GPSM3 OR5B21 NOX3 OR6C70 FOXO4 RPGRIP1L SMPD3 OR4E2 PPP1CB STK4 DNM2 RBP2 SMAD4 RBCK1 EGR1 CTBP2 TUBB4A PPP2R1A GNAT2 CD55 AGO1 SQSTM1 TBL1X WDR19 MAMLD1 SLC38A9 GFRA3 OR5H6 TNF ATP6V0A2 KIDINS220 H2AFZ MKRN1 OR2AJ1 GTF2A2 CCL16 A2M CBX2 OR4F5 SHB XCL1 ITPR2 COL6A6 RGS10 SUCNR1 FUZ PTPRA OR51Q1 SHC3 WNT10B PLA2G4A PSENEN LAMTOR2 OR7G1 ARPC4 RET GRM3 LEF1 RETSAT IQCE LRP12 TUBA4A ADM2 OR10AD1 ADRB1 STAM2 PHLPP2 IFT88 ABI1 IQGAP3 OR13C5 GNRHR CDC37 OR9G9 TAS2R13 SPDL1 APBB1IP FGF17 OR51L1 HIST1H2AB CSNK1E OR4N5 INHBB SSTR4 OR4C5 ADGRE1 TTR SYDE2 GLI3 OR4K14 OR56B4 RHOT2 DZIP1 POLR2K ROCK1 OR10G9 SRF F2RL1 ATP6V1E1 P2RY12 BUB1B MAP2K5 DLL4 PPEF1 FGD1 PTCH1 ARHGEF33 OR5AC1 FN1 KNTC1 PTH OR10H4 EPAS1 OR10AG1 SGO2 IKBKB PIK3R3 TAS2R46 LAMA5 CCL23 NRG1 CENPA KHDRBS2 PLCB4 OR2F1 MAML3 OR6C68 MST1R SMURF1 OR13D1 RAF1 NOG TAAR1 DGKD PSMA3 FGA F2RL3 OXGR1 PTHLH DHRS3 ESRP1 SPRY2 PTK2B TFDP1 NCK2 OR2S2 PRKCQ PSMD10 NEFL MMP9 SCT CENPM RXFP3 OR10G2 OR4K5 SMAD9 EIF4G1 FLT4 VEGFB COL6A1 OR2F2 TNRC6C GAB1 GNAT3 POLR2H NTRK1 GPSM1 LRIG1 SDC1 REEP5 COL9A1 AKT1 OR10A6 CDKN1B MKS1 BAG4 TFDP2 OR14A16 GNB5 PAG1 OR2L5 POMC OR52M1 ADCY7 OR5P3 NFATC1 AKAP13 PTPN12 ARRB2 MC4R TAAR2 RYK IFT172 SPC24 NGFR OR13F1 OR4E1 WNT3A CXCL1 CHRM3 GPR150 MYL12B GDI1 NPBWR1 GAS1 CLASP1 TCF7 TRPC7 LAMC2 OR2B3 LAMB2 FPR2 OR2V1 EBAG9 BAIAP2 TUBB1 OR9Q2 OR51H1 DNAJB1 INPP5B TNFRSF1A SCRIB FGF20 OR5C1 OR2W5 FZD10 MAPKAPK2 RAPGEF4 PML MAPK12 OPHN1 ARAP2 HTR1D ADH4 KAT2B ARHGEF18 SKP1 PDGFRA CX3CR1 KIF18A LPL GDF2 PRDM4 OR4N2 F2 GNG8 RHOBTB1 OR13C9 FAS NCOR1 RCOR1 CXXC5 RGS19 HIST1H2BN CXCR4 OR51F2 VAV2 PIP5K1A MYL9 FGF10 ATP6V1F DKK2 CAB39 TNFRSF10D OR2T3 NCBP1 RGS4 RASA3 VIPR2 PDE1C OR5D14 NUP37 MDK GPR68 OR8J3 RXRG EEF2K ARHGAP26 SST OR4F15 DYNC2H1 USP2 ARHGAP30 F11R OR1L1 GHRL PPP3CC FFAR4 TNS4 CXCL12 GPR35 OR2T34 PDE6B OR8D1 OR52E5 MLNR KIF5B PRKAA1 PYGO2 ARHGAP19 OR5AC2 NOXO1 WIPF3 CRHR1 YWHAG ECT2 RASAL1 DNER NRAS OR5R1 THBS3 RIT2 TTC21B HSPG2 OR9Q1 COL6A2 DUSP9 PRKCI OR4S1 PTPRU FGF23 STAT1 EREG FKBP1A GLP1R S1PR2 OPN1MW CHRM4 DLAT PRKCZ ETV4 NMBR OR10H2 FAM13B TAS2R31 NCSTN OR10T2 NTF3 DTX1 TNS3 GPAM TRIM27 KNL1 GPER1 OR2L2 GIP XCL2 DEPDC7 NUP133 PIK3AP1 ATP6V0C CD80 GTF2F1 OR4F16 CASP10 NPFFR1 ARHGAP17 PPBP RGS8 FYN OR10Z1 PPP2R5A HPN INS TGFB1 CXCL11 PDK4 NR4A1 OR14A2 PLEKHG5 GPBAR1 SMC3 TLR9 NEURL1 PKN2 SOX13 KNG1 PRKG2 RDH12 PSMA4 SERPINE1 OR4K2 DUSP8 ADORA1 RAPGEF1 ARHGEF12 ROCK2 SH2B2 PDE4D SKA1 GPR27 UBA52 FOXO1 PTBP1 SPPL2A SEC13 NR3C1 OR2A25 CXCR5 GNG11 EVL HSP90AB1 OR6C6 MYB PYGO1 COL27A1 PRKACA ARHGEF3 NF2 ARHGAP35 CALCB LPAR4 CYLD SPTBN1 ARHGEF7 ARHGEF39 OR52R1 CGA PTAFR RHOH STRAP DRD1 ELMO1 CYBA IFT57 OR8K3 OR2V2 OR9G1 PDE6G NSMAF ARHGEF2 CTTN CYSLTR2 ARHGAP32 RGS5 OR2T33 H2AFX HIST1H2BH MT-RNR2 CAB39L TAS2R30 KITLG AP2S1 OR14C36 NLN ADRA2C OR4P4 FPR1 CHN2 ARAP3 OR6C1 SEH1L SNW1 OR52E4 OR2G3 CDCA8 VCP PNLIP NCOA3 FGFR3 ARHGEF26 ELMO2 RNF31 CBL MEMO1 GPC5 IL2RG AWAT2 RSPO2 ARHGAP22 SPOP MED1 GPR183 TSC2 PRC1 STAG1 SOCS1 OR10H1 JUND STK11 PHB MAPK11 NPBWR2 ARHGEF19 NGF GPR83 AMOTL1 IGF1 ANOS1 ITGB3BP ATP6V1B1 OR4C11 USP4 OR2W6P RNF41 WNT11 LGR4 WLS ADCY10 MYH10 OR4C12 CHRM1 SRMS OR2B6 HTR2C OR52W1 CASR CYP26B1 CTNNA1 ARHGAP1 ADRA1B TAOK1 RAMP2 NPHP4 SYVN1 RAMP1 FMNL3 CHD1 OR10A3 GPR65 GREM2 RIPK1 BCR CAMK2G GNAO1 HTR7 SH3GL1 FZD9 IHH FSHR SUZ12 CDH5 ADGRE2 RASA4 TAS2R16 ATP6V0E1 GPC1 NTSR2 GNG2 GRM6 QRFP RGS22 INCENP OR2A4 ITGA2 CCL5 BCO1 DIAPH3 TJP2 SRGAP1 STAG2 GALR3 OR1N2 ATF2 FFAR2 WIPF1 GAST OR51M1 OR1K1 OR52E6 BMPR1A ARHGAP10 PPP1R14A NTSR1 CFTR GPRC6A GATAD2B MGLL OR10D3 LTB4R PDE11A GNG7 GNA15 ITGA2B TRADD CCL4 OTUD3 OR4A5 TAAR5 CXCL6 ADCY4 KHDRBS1 OR5I1 H2AFV CASP3 GUCY2F ACTB RBBP4 CDC14A OR1L8 DLK1 PTGDR PSMD13 PSMD2 RXRA GNB2 FGF1 TUBB2B XPO1 CMA1 KMT2D DUSP10 PLCB3 OR10K1 POLR2C CCR7 PDE8A REEP1 PLPPR3 RAD21 NPW PTCH2 OR5K2 OR1S2 RRH CSF2RB DLD H2AFB1 CREB1 OR7G2 GIPR COL9A3 PSMC4 GCGR DGKZ OR2D3 CAMK2B OR10S1 FLT3 CSF2 APOA4 ADH1C RUVBL1 GNAI3 ALDH1A2 SH3KBP1 PSMB4 CCNC DGKK PDE7A WWP2 PSMD8 TRIP10 KTN1 PDK2 OR6B1 AXIN2 OR14J1 PSMD14 CCR4 WASF1 FGG OR6K3 OR2T27 PTPN11 ARHGAP9 STAT6 FOXA1 AMHR2 OR4C16 OR10X1 CUL3 DLC1 TLE2 OR2B8P LAT SOX2 USF2 ATP6V0A4 TIAM2 COL24A1 BAMBI TEK HDAC2 EPS15L1 GPR15 USP8 TBL1XR1 TAS1R1 IGF2BP1 OR6K6 PRKAG1 PRKCB UBE2D3 GPC2 OR5AK3P TAS1R3 HES1 IL2RB GRK4 DUSP6 QRFPR ATP6V1D GRIN2B VAV1 ATP6V1C1 PCSK6 PSMB11 RASA2 HSP90AA1 METAP1 FGFBP3 ARHGEF25 NMS VEGFA GNRH2 OR2A42 OR52N1 SYDE1 OR2AG2 KIF3A OR14K1 OR51D1 ARHGEF11 ATP6V1H SKA2 CKAP5 CCL28 OR2T12 MDM2 OR1F2P WNT5A CYP26A1 OR5T2 RAG2 OR2J3 OR6C65 LAMTOR1 CXCR1 MYH11 XK RTP1 CDK9 CHUK LAMA2 MAPK4 IFT52 OR51B2 ADCY8 RGS13 XIAP CCRL2 PSPN OCRL MYL6 RBPJ OR4S2 MAPK14 SEM1 HIST2H4A GNA14 HIST1H2BO RASA1 PLPPR2 WWOX RSPO1 DUSP7 NTF4 SOX9 GRIN2C MADD AP2A1 CYP4V2 KLK3 RASGEF1A STAT5B RGS21 SMO POGLUT1 PIP5K1C CAMKMT OR5B17 RHOT1 RHOJ ATP2A1 WNT8B APC MAPKAPK5 OR2A2 OR4N4 WNT9A HCRT OR6C75 PSMB2 CILP DGKA OR5M3 PDE7B ADCY3 GRPR FGF19 RLN2 TLE4 CORT REEP3 SPTBN4 PTH1R VEGFC PGF MYO9A HRH2 AMH PRKAR2B PDHA2 JUP CD19 CLPS FZD1 SMAD7 TUBA3E PIK3R5 OBSCN MCF2L WNT6 FGB OPN3 OR5H15 HECW1 WNT4 PLCB1 ACKR1 PPP3CB OR3A4P SDR16C5 HCAR2 TULP3 OR10K2 RGS16 FZD3 PLAT CBX4 KLC2 SCTR OR6B2 CYFIP2 PRKCG CDC42EP5 ERBIN OR14I1 PF4 OR7A10 OTULIN MYO7A H3F3A NUP98 HIST1H2BD AHCYL1 FGF3 OR8U1 VWF GNAZ ATP6V1E2 CENPK OR4C45 AES SH2D2A BRS3 OR2H2 CHRDL1 CIT ERCC6L NCF2 OR10W1 SFN HDAC11 CHD4 PDPK1 CALCR CRHR2 ADCYAP1 DAGLA DUSP5 OR56B1 RASGRP4 IRS4 FLT3LG NGEF EED PPARD SOST CFLAR KDR OR56B2P OR11H6 MYH9 VIPR1 SPINT2 FGFRL1 FABP5 TCF7L1 CHD8 ARHGEF10 CAV1 OR52J3 EDN1 GPR37 TMED5 PSMC2 ERBB2 COL4A4 IL2RA THBS1 BRK1 P2RY4 PSMD3 PTH2 GUCA1A OR12D2 OR10J6P P4HB TRAF2 SDC3 SPHK1 OPRD1 BCL2 OR5M11 LEPR TAX1BP1 STAT3 BTK HDAC10 RDH10 ARHGAP5 HEYL KLHL12 DTX4 ATN1 KALRN EDN2 PHC3 OR1B1 WNT9B OR5T1 ZNF217 ELK1 HIST1H2AJ DAGLB ARHGDIB DOCK1 OR7A5 OR5D18 GRAP GNA13 OR13H1 OR14L1P ARPC1B CXCR2 OR1C1 RASAL3 GLI1 RTN4 HTR2B RICTOR GHRHR OR5V1 NMU SFRP1 SSTR1 OR5D16 LAMA1 PSAP NCF4 STAP2 MOV10 SPINT1 ARHGAP44 OR2AP1 PDE3B TRIM33 TNFRSF10B ARPC1A OR2B11 PSMC6 NTRK3 AKT1S1 FLNA BIRC5 HEY1 PPP2CB LDLR JAK3 ARHGAP33 AATF PSMB3 OR8B3 CALCA COL11A2 PIP5K1B ADCY9 AP2A2 CCR5 NUDC HIST1H2AD CGN MYH14 AGO3 OR52P1P ADH1A IL33 NMT1 NELFB RSPO4 P2RY13 OR9I1 RGS12 ALDH8A1 NPY4R PORCN UCHL5 GRM7 OR5AL1 RARA RPS6KA5 PDGFB NPB HTR1F PKN1 TRH CXCL3 BMPR2 HRH3 OR2H1 AMER1 FGFBP2 OR8D2 COL4A3 RAB4B HRH4 ADCY1 OR2T35 PDGFRB OR10G8 ARRB1 CCDC88C IL3 OR4B1 HIST3H3 NCOR2 WNT10A TRPC6 ICOS FZD8 ADRA2B ARHGAP23 OR10R2 OR5J2 MRTFA GALNT3 ADGRE3 MYO9B OR2T29 CLIP3 GFAP CHRM2 GRM2 RGS11 MTA3 LGR5 LPAR2 CENPS PRKAR1A OR9A4 RNF146 PSEN2 RPTOR OR52L1 OR10P1 WWP1 OR2J2 IL6R P2RY10 OR5K3 APOE OPN1LW GNAI2 PRKCH TAB1 TSHR OR4D9 RIPK2 STK3 CFL1 RXFP2 OR1J4 KIF2B HGFAC OR5K1 TUBA1B MAF1 VPS29 GPR20 DACT1 PTGDR2 OR4A8 RHOC ATP1B4 OR8B4 LRP2 ITGA3 POLR2F PTPRS GTF2A1 WIPF2 LRRK2 FOS APH1A NCAM1 ARHGAP39 ACVR2B PPP1R15A CCR1 OR5AN1 TUBA1A GNG13 OR10AC1 PIP4K2B OR4D1 DLGAP5 OR5W2 OR56A5 STARD8 DYNC1I2 RHOG FGF7 OR3A3 GNAI1 FLRT3 GRK1 EFCAB7 TAS2R38 OR4K3 FLRT1 OR2T1 OR4Q2 ARHGEF37 ARHGAP24 PIP4K2A TUBA4B GNGT2 CAMK2D MBD3 SRC OR2T10 YWHAQ OR6N1 GRIN2D MC1R ARPC3 OR5A2 GAL RHOD CLIP1 RTP3 FRK PFN1 OR10G7 NR5A2 SAA1 RDH5 OR10H5 TAB2 OR5H2 SDC4 CPT1B ATP6V1G1 DYNLL2 AGO2 OR52A1 RACGAP1 CTNNB1 FLRT2 LPAR5 SHC2 ATP6AP1 ARHGAP45 CLTB IL6 TFF3 FGF5 PTGER2 TAS2R3 PPP2R5D METAP2 NMUR2 PCSK5 OR52A5 ABL1 MAPK7 SGO1 PSMF1 MIB1 VPS26A LAMA3 GRAP2 SH3GL2 TIA1 APH1B OR6K2 OR11H4 ADRB2 PPP2R5C COL1A2 ARHGAP21 ALDH1A3 FZD5 TIAL1 GFRA4 IRS2 OR8H2 PSME1 MEF2A RGS6 OR2Y1 TAS1R2 TACR1 ACTR2 HHIP CRKL APOC3 ABCA4 PHC1 OR1Q1 ITPR3 AMOT SIRT6 ST3GAL3 OR52I1 C5AR1 CXCL2 OR10J3 CNKSR2 OR2M3 OR4A47 REST SAG WDR83 STAT5A OR2D2 CCNT1 USP13 HNRNPA1 OR4K15 CXCL13 GPR17 SPPL2B ARHGEF10L GPR176 OR1L6 PYY OR2L13 RBP4 FCER2 GHSR AGRN INSL3 KIF5A OR51I1 OR5AS1 PRKAA2 SPRED1 IL17RD AKAP9 OR10V1 PDGFA LAMTOR5 HIST1H2AC HIST2H3D LEP CHN1 PTGER4 NOTCH1 MCHR2 OR5M1 PDE4A GATAD2A KREMEN1 F2R GSK3A RFNG HIST1H2BC CDK2 OR4C13 ADAM12 KSR1 OR6X1 P2RY6 PRKACG PDGFD TLN1 DUSP4 RGS18 RRAGD PAQR3 HSPB1 DERL2 CRABP2 DYNLL1 OR7C2 OR2AK2 ATF1 OR9K2 RPS27 CXCL9 NRTN PIK3CA SOS1 MMP3 KIF7 OR8H3 SOCS3 B4GALT1 TRAT1 WNT2B FMNL1 RANBP2 PEA15 OR2M4 OR8G2P MIB2 GNG4 PSMA6 GUCA1C HCRTR2 PTEN UTS2 HGS ARHGEF4 PSME3 OR52L2P OPRK1 YWHAH PREX1 RASGRP2 CENPC SALL4 PELP1 RXFP1
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Hierarchy Landscape

The following plot represents the hierarchical landscape of 'Signal Transduction'. The hierarchical tree allows to click on the pathways with children (black border) and continue the exploration. All nodes are colored by their source (click on the map for the legend) and cross-link to the original pathway page.

Sub-Pathways

About

ComPath is developed and maintained in an academic capacity by Daniel Domingo-Fernández and Charles Tapley Hoyt at the Fraunhofer SCAI Department of Bioinformatics. This web application relies on data loaded from KEGG, Reactome, and WikiPathways Restful APIs, as well as MSigDB. More information here.