Signal Transduction - Pathway Page
Name Signal Transduction
Resource Reactome
Genes ACTB PRLHR POLR2L TUBB3 FGF7 OR14C36 RPS6KA3 OR51L1 REEP3 CYP4V2 AXIN1 HSPG2 PKN1 RSPO1 THBS1 ALDH1A2 ARHGEF10L ATP6V0E2 PSMD9 PRKACB PTH2R COL4A4 AP2M1 OR9G9 KSR2 GNAS GNG2 SRGAP1 GREM2 OR10K1 PDHA1 STRAP OR5H14 FURIN OR4K5 RHOT2 NTF3 FGF6 ARHGAP24 SYVN1 KAT5 MGLL TCIRG1 CYP26A1 CDC37 IER3 PIK3R2 FLRT2 FGA OPRK1 OR52B6 OR2J1 GHRH OR10A2 LPAR5 OR2A2 TUBB8 FGF17 TBXA2R OR3A2 OR2L8 TNFAIP3 KIF7 OR52E8 CYLD MYH9 CAMK2G MAPK11 ATP6V1G2 FOXO1 OR10C1 GFRA4 IL2RG OR10G4 LPAR6 PSMA7 AKAP9 PAFAH1B1 SPRED1 PPEF1 OR2L13 PDE8B TGFA OR1F12 OR52N1 PAG1 GAB2 WNT10A PRKAA2 TAAR2 TAS2R40 OR2T12 PDE4C SPTAN1 STK11 EREG NRG2 RIT2 EPS15L1 ADH1A LYN CCL16 RGS2 WDR35 PIK3C3 OR2D2 BDKRB1 FZD1 OR56B4 BCL2L11 PYY HIST1H2BK SPHK1 DYNC1I1 CSNK2A1 SMC1A PRICKLE1 ARHGEF18 ADCY1 COL6A3 LRP12 GNAI1 LIMK2 OR4K13 PPP2R5E OR4D6 CLASP2 OPN5 OR8U8 PSMB5 WASF3 GNG4 HTR6 GLP2R LAMA1 PRKCD KDM4B OR51B4 ITPR3 MEF2C OR4M2 CHRM2 GRAP2 HHIP RBPJ SHB OCRL C5AR1 ARHGAP33 POLR2K FOXO4 OR4F21 GNG8 ATP6V0A2 OR5P2 OR5A1 CKAP5 PSMD2 ADRB2 RASGRF1 ADGRE5 ARHGAP11B OR2B6 EIF4E FGF20 IFT172 COL9A3 LAT NUP85 MTA1 DTX4 CLTB GTF2F2 DNAJB1 PIK3R4 OR10G8 PDE6G CLIP1 OR4C15 HEY2 PPP1R12B CCRL2 ALDH8A1 RBP2 CALCRL SHC2 PTK2 ARHGAP21 PKN2 PSMB2 DGKD ADCY10 PBX1 GPR32 PTPRS TLE1 HIST1H2BB OPRD1 MAPKAP1 CCR4 GFAP PSMA3 HTR1F OPN1MW ELMO2 AHCTF1 ARAF PROKR2 GFRA1 ATP6V1B2 FZD10 SH3GL2 ECT2 NPY4R OR5R1 YWHAZ CREB1 PPP2R5D GNA13 OR8H1 C5AR2 VEGFB COL6A6 ARHGEF39 OR7C2 OR5H2 FGF5 MTA2 OR2B11 CCL5 PLCB3 F2RL1 EPN1 SOX13 KSR1 CBX2 ADAM10 IL1RL1 PSMB1 RPTOR OR1K1 ABHD6 HIST2H3D ETV4 OR1D4 DGKK RHOBTB2 NTSR1 OR10AG1 OR10Z1 RDH12 MED1 CHRM5 HIST1H2BA AXL OR4F15 OR2J3 CCNC BDKRB2 AXIN2 OR8G5 OR2AJ1 FABP7 OR56A4 CSNK1A1 OR10T2 HSP90AB1 OR14A16 TAAR3P WNT6 INS PTPN18 RXRB OR4K1 OR13C3 USF2 SOX2 IGF2 GIP PIK3R1 GLI2 SCUBE2 FGF1 RXFP3 KEL CYP26B1 SPRED3 OR2W5 ATP6V1C2 MLST8 OR5B3 RALA OR2A12 ATP6V1A APOE OR51E1 OR2Y1 PSMA6 SH2B3 ACVR1B OR10A3 OR10H2 TAS2R14 OR5AC2 APP CALCR USP34 PTPN1 OR2V1 PSMB6 BIRC5 MAD1L1 FAM13B OR56A5 PRKCI OR2G3 CPT1B ARHGAP8 COL6A5 ARHGEF6 COL5A3 VEGFD NOX3 RAPGEF3 TUBB1 GPR17 KIF18A OR5B21 S1PR4 OR6V1 GPR84 CBX8 CASP10 IL17RD GRM3 REEP2 OR4D5 CUL5 ARHGAP28 DGKE OR6N2 NPY5R NUMB PSMA2 IRS4 LAMA5 ACVR2A SHARPIN NCOR2 ADGRE1 RING1 LHB ITSN1 RELA CNGA1 FLT3 UBE2M CAMK2B BAMBI OR56A1 GGA3 OR1L3 TAS2R7 ESR2 PPP2R5A RGS19 NMB OR8J2 OR5T1 OR4A16 POLR2B FGG OR10W1 NPY SERPINE1 TNRC6C GNG11 ARHGAP9 HNRNPM OR4A8 JUP PROK1 ITGB3 JAK3 OR2H2 PAQR3 PTPN11 OR5F1 POLR2F PXN DYNC2H1 HES1 RAPGEF2 OR9A1P NPBWR1 CYBA DAGLA CENPK CCR7 PPY ROR2 DISP2 OR12D3 CASP2 NSL1 AGO2 OR3A4P ATP6V1D TUBB2B CSN2 PSEN2 GUCY2D PPP2R5C OMG NLK HIST2H2AA3 PSMD3 DIAPH1 ULK3 OR52W1 LCK FOS MYH10 ARHGEF1 OR51B6 LEP OR51A7 RGS22 KL OPN3 OR2T1 FLRT1 OR52R1 HIST1H3A PSMF1 SPINT1 PRKCZ OR51Q1 RACGAP1 PDGFA NDEL1 PSMB9 CAV1 SMAD3 BIRC3 RXFP4 EPS15 SOX17 ATP6V1E2 IRS1 RUVBL1 WNT2 FNTA ARHGEF2 MIS12 CENPT SAA1 CXCR5 RPS27 PSMD5 INTU CDK5 NTRK1 HIST2H4A NFATC1 OR4F4 NRAS PIK3R3 TSHB OR4N5 GAS1 AKT1 OR5L1 AVP RAMP3 DHRS3 SMAD4 IL33 CXCR4 OR14K1 RDH10 OR4A5 RHEB OR2S2 MFNG CITED1 POLR2G GRM4 KIF2B PPP3CA GPC6 FKBP1A YWHAQ DYNLL2 OR52B2 OR5H1 RGS4 DNER RSPO2 SSTR3 SMPD3 BRAP CCL1 CCL4L1 ELMO1 OR2T11 PIP4K2A COL6A1 ABHD12 MAML1 AKT3 DUSP10 CALCB VRK3 SDC2 LINGO1 CCR8 HDAC4 PKN3 FZD5 RGS7 GRM7 OR1L6 VAV3 SFRP2 DYNLL1 TERT TTC21B TRAF1 GPAM EP300 OR9Q2 GRM1 ERBIN CHD1 USP9X TACR3 VPS26A NUP133 CYSLTR1 BEX3 GNB3 EDNRB FGFBP3 TRIO CENPH PPP3R1 OR1A1 BCO1 PDHX OR6C4 CXCR6 FZD3 COL2A1 AMH WIPF3 RAP1A FGFR1 PFN1 LRP1 OR2A7 XPO1 CGA GRK2 RHOC NMS BAIAP2 FGD1 RHOQ OR4K15 OR13F1 ATP6V0B OR2W1 UBC TAAR1 MMP9 BCR NCF1 RBBP5 PTCH1 OR6B3 FGD3 LRP5 RHOD RTN4R OR2A5 RGS20 BCL2 AKAP13 OR5K2 P2RY2 TAS1R1 NPY1R POLR2I DACT1 PSENEN GATAD2B DHH OR14I1 PLXND1 OR10A7 TIAM1 CENPL SKIL PAK1 CHEK1 FRS3 SOX3 OR6Q1 POLR2A BRAF WASF2 HIST3H2BB OR5AC1 IL2 REEP1 MCF2L SMAD2 GPR45 TNFRSF1A DVL3 HTR2A IGF1R SDR16C5 BMI1 GLP1R CXCL13 RHOA OR2T34 FZD2 GUCY2F OR5G3 TACR2 OR7A17 PDE2A PDE7A CENPC AP2B1 PPARD BTRC LHCGR DUSP16 RAMP2 STAT3 ITGA3 NLN PRKACG DGKQ NR3C1 EDN1 DIAPH3 OR51T1 B4GALT1 KPNA2 TEC HRH1 SPC25 SNAI1 GPR150 ATP6V1G1 ITPR2 NUP37 ACVRL1 GRM6 KHDRBS1 WNT4 OR4C13 RGS6 OR52E2 ARHGEF7 RPS6KA1 APLNR PRKG2 GNAT1 SMPD2 SRGAP3 HGS RSPO3 AGO4 DGKH OR7C1 PHLPP1 YES1 ARHGAP26 LDLR ARHGEF10 CHRDL1 PSMD10 ATP6V1F OR52N5 CSNK2A2 EZH2 OTUD7B OR1C1 CCL27 VIP DRD3 CRABP1 CCNT2 GNRH2 CARM1 APC DUSP6 OR51G2 HIF1A FOXH1 SMO OR1J1 NOTCH4 MLN CCKBR SP1 OR4X2 LTB4R2 NRTN OR2M4 SPOP GNG13 LRP8 LAMA3 PELP1 GRK4 AKR1C4 LAMC3 IFT140 SMURF1 ATP6V0C RHOV TAC1 DLL4 PTEN OR10G7 SPTB POLR2J OR52D1 AURKB YWHAG ARHGAP5 PPP1CC HCAR1 OR1N1 ADGRE2 ARHGAP23 MST1 CSK ARHGDIB CDK1 AKR1B10 OPHN1 COL4A1 OR6C76 QRFP INCENP RGS14 DUSP3 CX3CL1 OR52K2 OR10R2 PREX1 RHOF RASGRP4 PHLPP2 PSMD1 PIP4K2B RALGDS ADM2 TJP2 OR2F1 ARHGAP22 OR2B2 ACKR3 PDE4D AMHR2 RETSAT ABCA4 PLPPR3 TUBA1A RHPN1 FKBP5 CILP PSME3 PDK3 NTRK2 HCRTR2 ADM PRKCH KHDRBS3 SCAI CXXC5 ZW10 OR5B2 LEO1 PIK3AP1 VPS29 CHD3 SHH MTNR1A USP7 NPFF NFKBIA COL1A1 SDC1 EBAG9 GPR183 PTPRU OR10X1 CXCL2 MCHR1 KRAS GPRC6A MYL9 OR9G1 NUF2 OR13C4 BCO2 S100B INSR DVL1 YWHAE TUBA4B RFNG PLA2G4A HGF ZNRF3 OR6X1 KDM4C RTN4 RIPK2 CXCL8 ZNF217 CRABP2 MAGED1 IL3 TFF3 OR7A5 PDK2 OR4C16 PLK1 OR12D2 WNT9B PPP3CB PLG PTGIR PDPK1 GNGT1 RICTOR CXCR3 ARRB2 EDNRA IHH OBSCN OXGR1 TUBA1C ADCY7 ARPC3 FGF4 RRAGC OR10G3 ACTG1 HCRT PSMB7 OR1E3 RBFOX2 KREMEN1 H2AFX HDAC3 PSMC3 HRH4 PTGER2 WIPF2 OR5A2 GUCA1C OR7G3 PPP5C OR8H2 GNB5 FZD8 EED ARHGAP45 PSMD12 CLASP1 TCF7L1 OR5W2 PRKAG1 DNM2 DKK1 PIP4K2C GPR39 RIPK1 DLC1 TAGAP MLNR ARHGAP19 CAB39 NF2 TGFBR2 OR10Q1 RBBP4 RLN3 ADAM12 FGFBP1 GPC3 INSL3 ARHGEF5 DUSP8 DVL2 DOCK1 ITPR1 PSMA4 E2F5 NTRK3 CD28 OR1P1 OR52Z1 SH2D2A LTB4R GRM2 PPP1R14A SHC1 RSPO4 KIDINS220 PPP1CA RBP4 AKR1C1 OR1J4 PDE7B OR8A1 NOTCH2 SALL4 PLEKHG2 NOTCH3 PTH GPC5 GALR2 TAS2R8 ARHGEF38 OR7G2 DUSP2 CCK PEA15 SEPT7 WASL LGR4 PTGER3 GNA12 CENPO TAS1R2 OR52L2P OR7A10 RHOBTB1 OR1N2 LEF1 OR5T3 TNFRSF10B CDH1 RGS12 NOTUM GTF2A1 CASR PTGDR2 OR1J2 CXCL12 OR4E1 P4HB DRD2 ACVR2B STK3 ADCY4 RGS13 OR2C3 CCL20 C3 OR1E1 TGFBR1 MAPK3 FGF22 GCG TUBA1B OR13D1 P2RY1 KIF3A WNT1 SSTR4 GRIN2C OR6B2 GDNF GPSM3 RANBP2 PSMD11 WNT10B BAX SDC3 KIF5B STAT6 KCTD6 OXTR CDC14B PDE8A ARHGAP11A DYNC1I2 PRC1 TRIM33 SEC13 OR4K3 RDH13 OR51F2 ESR1 TRIM27 OR52M1 DYNC1H1 GNAT2 FLT4 SOCS6 FZD7 OR4F5 PIP5K1A OR11L1 ARPC4 STAT5A HIST1H2BO ITGB3BP PRKCQ CSNK1E CDKN2B TAX1BP1 CDC42 PSMC1 OR4D2 OR11H7 NPSR1 CDH5 NOXO1 NTF4 OR4Q3 CNKSR1 PIK3CA ARHGEF12 PSME4 RAF1 VWF WWP2 OR5L2 RGS3 CENPI DNAL4 BMP10 WAS OR5K3 RGS1 SNX3 POMC DGKG CHRM3 CENPA MYB EGF OR4S2 ITGA2 MEMO1 LATS1 HHAT CNTN1 KHDRBS2 ATP6V0A1 LPAR2 OR9I1 EPAS1 GABBR2 RASAL1 PDE3A MKNK1 OR10H3 MDK ADORA2B BRK1 MMP3 OR6K2 RHPN2 OR7E24 IQGAP1 MRTFA TUBB2A LRAT OR51G1 WNT5A ZFYVE9 ARPC5 CCR3 ARHGAP44 DAAM1 OR6C74 PIP5K1C RLN2 CDCA8 FLT3LG OR2A4 PTAFR RDH8 COL11A1 ABL1 DRD1 ADRA2B CCL13 OR4N4 IGF1 HTR7 RBP3 CSNK2B CXCR2 PPP1R1B RUNX3 JUND CDKN1B ADCY5 COL6A2 COL9A1 TAB1 SRGAP2 THBS3 PDE4B PDGFB EDN2 CCR1 PGF ELK1 NF1 XIAP AGO1 LIMK1 SCMH1 OR4C45 SH3GL1 OR2AK2 ADCY3 WWC1 SH3GL3 ATP6V0D1 DUSP1 BTK SEM1 OR2T7 CTSD OR1B1 ADRA1D CCNE1 MAG FGF9 EGR1 SKA2 GPC2 GLI3 TAS2R10 PNOC ARHGAP39 CDC42EP3 OR8J1 OR2W3 PPID F2RL3 RPS6KA2 OR4C11 CYFIP2 TNKS OR2L3 WWOX KMT2D CTNNBIP1 DLD CTBP2 HIST1H2BC RLBP1 ZWILCH OR5AR1 HSPB1 RBCK1 CENPU ARAP2 HIST1H2BN OR52K1 CENPP RAG2 PHC3 FGFRL1 MYL12B KBTBD7 E2F3 MAP2K5 YY1 OR51A2 SH2B1 OR13C9 IL3RA GABBR1 CNR1 JAK2 HPN ADORA1 BMPR2 OR13C2 FGF10 OR52N4 RDH16 LPL HDAC9 XK KISS1R TRPC7 RNF2 PDE11A S1PR5 CAMKMT DTX2 OR51S1 HNRNPH1 GRK7 ERBB2 DEPDC1B MARK3 MEF2A VIPR1 RPS27A CCL28 PGR SUFU MST1R SYK RGS18 OR52E1 TTR GPR37L1 AR OR10AD1 OR10A5 RGS16 RCVRN FUZ NPY2R BCAR1 PPP2R5B GRIN1 SRY GFRA2 MC5R RAPGEF1 DYNC1LI1 OR11H2 GNGT2 SUCNR1 AP2A2 OR6Y1 MYC UTS2B CHD4 LRP10 PDK4 ATP6V0A4 AKT1S1 RDH11 BUB3 KLK2 DLL1 OR14A2 PDE1C WWP1 OR52H1 TBP INPP5B RHOT1 TMED5 TAC3 TRAF2 LAMB2 APOA4 DOCK3 VANGL2 NCKIPSD MAPKAPK3 MYL6 GOPC CXCR1 XCL1 MYO7A COL4A5 OR1D5 FPR1 ADAM17 APOC3 NEFL FGF18 TAB3 KDR OR4L1 RAD21 BCL9 FAS OR8J3 APOA1 PLCB4 CENPS PTCH2 SSTR2 OR10G6 ARHGAP18 ATP6V1H UCN FGD4 ARRB1 FRS2 OR2AG2 MAP2K1 TAS1R3 PHC1 OR5AN1 NET1 GDF2 CALM1 SRMS TYK2 OR5D18 OR6P1 CD19 TJP1 PRKAR2B OR10D4P ITCH TUBA8 GATAD2A GRK6 RET SDR9C7 SPPL2A PRLH OR56B2P NPW ADCY8 SGO2 PROK2 P2RY6 MC3R CRKL ATF1 KLC4 FGB ARHGEF35 CENPF OR51B2 TAS2R5 IRAK1 NTSR2 COL3A1 GLI1 PARD3 PTHLH YWHAB RALBP1 OR51V1 ADRB3 PPP2CB ADORA3 RNF111 SPPL2B ARHGEF37 PSMB3 SOX6 IL6R RASGRP2 OR8K3 ARHGEF33 RXRG GPC1 LFNG TAS2R42 PSMC6 PSAP MAPK4 TUBB6 TIA1 USF1 OR4E2 GALR1 OR11G2 PDE3B CCNK OR6C70 FGFR4 VPS35 OR8H3 PTGER1 PRKAB2 TAB2 PDHA2 CXCL6 STRA6 ROPN1 FABP5 KANK1 PAK3 OR13C8 BMPR1B OR5AS1 WNT16 RPS6KB1 OR1S2 DUSP5 ARHGEF17 OR9A4 PHB PENK OR10J1 GNAO1 OR52E6 TRIP10 OR1G1 BUB1B PLPPR4 FPR3 GPR143 PTPN3 HCAR2 P2RY4 ABI1 CBX4 JAG1 OR51I1 ARHGAP4 APH1B DYNC1LI2 KIF14 GDI2 TNF TEK ARHGDIG IKBKG SEH1L GNRHR CRH MC1R LRIG1 POFUT1 RCOR1 EEF2K MCF2 ITGB1 RBX1 OR52P1P ARHGAP12 RAB6A OR2I1P EFCAB7 SAG PDE10A ARHGEF25 RASA1 ANGPT1 CIT OR6N1 AMOTL2 OR2T3 GPR176 ARHGAP6 PIK3CG CAMK2A PRKG1 WNT8A GRM8 OR4C5 REEP5 PLCB2 ADCY2 E2F4 PPP2R1B CER1 OR4K17 PTGER4 LPAR4 OR5AU1 SH2B2 PTGES3 OR6S1 OR10G9 HIST1H2BJ CNGB1 TLN1 HEBP1 ATN1 BOC GRAP CBL GATA3 USP2 PTCRA FGF19 CCL23 TGIF1 GRIN2B NUP98 H2AFZ PROKR1 GNAZ IQCE OR52E4 OTULIN ERLEC1 ACVR1C FMNL1 OR5M11 GPR20 TAS2R39 HEY1 SLC24A1 OR5B12 ACTR3 OR4A47 GPHB5 OR5K1 PPP2CA FOXA1 LEPR CXCL16 AKT2 MAPK12 OR6J1 UCN3 AVPR2 NCOR1 A2M ACTA2 PLXNB1 OPRM1 CLTA PCSK6 OR4X1 POLR2C FMNL3 DOK1 OR10J5 MIB2 OR2A42 HTR1E SSTR1 KTN1 CCR6 KLK3 RGS8 STRADA TAS2R19 OR52I1 CDON TAAR9 PPP1CB GNB2 FLT1 HDAC11 OR8D1 NPFFR1 ICOS PCSK5 GNA11 RASA3 KNL1 DGKZ OR10A4 USP8 OR1E2 ARHGEF26 PLAT KALRN NCKAP1L DIAPH2 PSMB11 ATP6V0E1 EIF4EBP1 OR8K5 SPTBN1 FYN GPR132 ANOS1 NDC80 KLC2 CALCA OR4F6 TAS2R4 EDN3 OR2G6 OR5J2 NCBP2 GSK3B NOX1 OR6K6 NRG1 KAT2A PTPN12 RGS10 PTGDR GMIP CCKAR REST PYGO2 STAT1 DHRS9 MAP3K7 OR2T29 HSP90AA1 HDAC10 OR5H15 TAAR6 IL6ST TAS2R30 HTR1B PSMD7 PPP1R15A MAP2K2 FSHB PSME2 CLIP3 CHUK ZWINT OR10S1 PIK3R5 CRK RARA OR9K2 ARHGAP30 ARHGAP36 FGFR3 MOV10 KREMEN2 CHRM1 SOX7 PARD6A SOS1 B9D2 DUSP4 USP15 WNT7B NUP43 OR2W6P ABI2 PSMA5 FADD F2RL2 CTTN TMED2 OR13H1 TCF7L2 ADH1C SYDE1 DGKA LAMTOR4 OR4F17 ATP2A1 SNW1 RRAGD MAML2 OR5B17 KIF2A SPOPL OR2T2 OR51J1 OR5AL1 LGR6 OR2T35 TFDP1 CAB39L OR51I2 RAG1 RNF43 EGFR CCND1 NEURL1 STAG2 OR10P1 GALNT3 OR2M2 ACKR1 WWTR1 HRAS OR4P4 OR11H1 RALB XCR1 OPN1SW PML PSEN1 TAS2R9 OR10J6P PLPPR5 RANBP9 PTPN2 OR13J1 NCF2 PRDM4 STUB1 AMOTL1 WASF1 NUDC PDGFC SPP1 FGF16 ADGRE3 PRKCE FOSB UTS2R MAML3 XCL2 CENPQ OPRL1 DZIP1 F2R GNG10 ADCYAP1 RNF146 GPR68 GNAT3 RIT1 GNG12 CCR9 IFT57 AP2A1 PEBP1 CBY1 AGTR2 PRKACA UBB IL1RAP PPBP OS9 CREBBP OR8B8 DUSP9 IKBKB OR5K4 TBL1XR1 NCBP1 METAP1 WLS PTH2 KDM1A OR52A5 GNAI3 PRKAG3 RASGRF2 NCOA1 PTH1R GFRA3 OR4C12 ST3GAL4 TSC2 FSTL3 OR8B3 HIST1H2BH FZD6 ARF6 NTS FER COL4A3 OR9Q1 NCAM1 RASA4 GNG7 NCOA3 IL5 FGF3 WNT8B H2AFB1 GIPR OR10J4 OTUD3 ALDH1A1 CDC42EP5 ATP6V0D2 LAMA4 ACKR4 ATP2A3 OR1L4 ATF2 TAAR8 MET NMT1 GDI1 PSMD13 CNR2 TFDP2 ROR1 MYH14 OR6T1 FGF2 LAMC2 FRAT1 GPSM2 MAPK6 OR7D2 OR2H1 BUB1 MDM2 GPNMB OR52J3 AWAT2 PCP2 OR1A2 MAPKAPK5 NPHP4 PDE1A ATP1B4 APH1A GRK1 OR52E5 TP53 KLC1 TNS3 PTK6 UBA52 RAC2 WIF1 RGS21 UTS2 NMU STARD8 CSF2RA CXCL10 PMF1 OR8U9 COL27A1 PRKAA1 LIN7B RRH UCN2 SHC3 KISS1 OR10J3 DUSP7 CDC25C C5 MAPK14 SOST AGT ATP2A2 CSF2 STK4 HIST2H2BE CASP3 OR10K2 FST ATP6AP1 BCL9L SCRIB CSF2RB KNG1 SMAD9 PSMD6 OR10G2 ARHGAP35 APOC2 AMER1 DOCK7 RAPGEF4 HECW1 NGFR GPC4 STAM2 RARG SYNGAP1 GRK5 OR2B8P P2RY13 ARTN SMAD1 EVL PLCB1 RPS6KB2 ANXA1 CCDC88C SRC OR11A1 UCHL5 ARHGAP40 YAP1 SAV1 ADORA2A OR4D1 CAMK2D KLC3 ERBB4 CXXC4 PLEKHG5 HTR2C SPRY1 IL6 SYDE2 PTPRK MT-RNR2 OR8U1 F2 NRG3 GPR27 CCL19 RTP5 PSMA8 PDYN COL9A2 SCT DKK2 RHOU CENPM MEN1 CYSLTR2 OR7D4 ROCK1 TCF7 OR2T6 RRAGB OR4D9 OR2B3 FNTB PLB1 CDK5R1 TAS2R31 VEGFC TAS2R50 CNKSR2 NPB PPM1A MUC20 P2RY10 FBXW7 OR56A3 TAS2R41 GRB10 OR6K3 CLTC HIST1H2BD WNT11 DLAT APBB1IP STAT5B COL4A2 ST3GAL6 OR4M1 PDGFRB FKBP4 OXT APOA2 RAC1 NEURL1B PRMT1 OR5M3 LAMTOR1 BDNF UBE2D1 S1PR1 GHSR HTR1D CD86 MATK TACR1 RBL1 OR6M1 MAMLD1 ST3GAL3 ATP6V1E1 TIAL1 OR2L5 CTNND1 PTPRJ TAS2R38 BMP2 ADCY9 OR52A4P RPS6KA5 PSMC2 AMOT HDAC6 GAL POGLUT1 SPTA1 MOB1B CFLAR CENPN OR2Z1 FGFBP2 NCF4 KIF5A GUCA1B LATS2 SMAD7 CYBB OR2M3 NDE1 RAB4A RPGRIP1L AHCYL1 RXRA DGKB PHC2 KNTC1 OR7G1 H2BFS FMNL2 OR9G4 CCND3 OR7A2P PIP5K1B OR4D11 NRG4 COL5A2 MTA3 PRKAB1 FAM13A CORT MYO9B USP21 PRKCA GPR37 GRP UBE2D3 H3F3A GRB2 OR56B1 SPDL1 TBL1X ARHGAP42 ATP6V1B1 OR2K2 HTR5A SDC4 PDGFD PSPN OR8B4 TAS2R46 VCL DRD5 LAMA2 RASGRP1 OR10AC1 OR8G1 OR4F16 PMEPA1 OR6C6 HTR1A THEM4 MCHR2 STARD13 NELFB LAMTOR2 OR2J2 GNRHR2 NUP107 HIST1H2AB STAG1 RASAL3 HDAC5 JAK1 CDK9 TRAT1 MTNR1B OR6F1 OR1L1 OR2C1 SPINT2 TUBAL3 TAS2R45 ARPC1B GNG5 OR2A14 CXCL3 PRKAG2 OR2M5 ALDH1A3 HDAC7 OR10H5 OR2M7 RBP1 ARHGAP29 CBFB RAB4B IRAK4 THBS2 RASA2 OR1Q1 ARHGEF4 HTR4 LRP6 GNG3 GPR161 HIST3H3 SOCS3 GPBAR1 RGS5 MTMR4 CHD8 APOB RNF41 FFAR4 OR5AK2 OR13G1 GALR3 TSC1 OR3A3 PTBP1 HNRNPA1 ARHGAP10 CCR5 OXER1 NRIP1 PIK3CB OR4C3 OR6B1 PLPPR1 GHRL GPSM1 PNLIP ARHGAP17 HIST1H2AC TAS2R16 GPR4 RANBP10 ARHGAP25 TRPC3 PTK2B AGRN SPTBN2 OR5H6 OR6C65 KITLG RAMP1 LRP2 LAMTOR3 CDK4 H2AFJ IFT88 IGF2BP1 MYO9A NOS3 TGFB1 HDAC8 LRRK2 MAP3K11 LAMC1 NGF FFAR3 OR2AT4 ARHGAP1 JUNB PIK3CD PF4 CXCL11 QRFPR ESRP2 RACK1 OR51D1 IFT122 TRHR TLR9 SKP1 PRR5 OR1M1 NPBWR2 DEPDC7 FGD2 DLK1 SSTR5 S1PR3 ITGA2B WNT9A SOX9 GNRH1 TAOK1 DRAP1 OR8G2P GPR31 POLR2D OR11H6 RNF31 ACTN2 PRKCG S1PR2 SRF NRP1 SQSTM1 HTR2B ARHGEF16 DHRS4 GRB7 TNRC6A OR8B2 PLPPR2 OR4A4P BIRC2 SEL1L INSL5 OR1S1 CSNK1G2 AVPR1A OR6C1 ADRB1 NMUR2 MAPK1 PRKAR2A OR5AK3P CBX6 HRH2 TLE3 PFN2 OR8D4 NEDD4 CXCL5 CYFIP1 MOB1A ATP6V1G3 LPAR3 SNAI2 GAS8 TAS2R1 SMAD5 OR2T33 COL5A1 TRPC6 OR10H1 OR6C3 TLE4 NFKB1 OR4A15 RYK TIAM2 ROCK2 TAS2R20 CPT1A ADCY6 GRK3 CD80 RXFP2 OR8D2 RGS17 P2RY11 NPFFR2 OR5I1 SFPQ USP13 MECOM SPRY2 C3AR1 TNFRSF10D TFF1 GTF2F1 OR52L1 FRK NMBR ERCC6L TRIB3 SPTBN4 IQGAP2 VCP TUBB4A SKA1 NCK2 PSMD4 TRAF6 MKS1 SPTBN5 ARPC2 CDC14A RAP1B CUL3 ADRA1A OR52N2 OR10H4 PAK2 RGS9BP FGFR2 MKRN1 EVC JAG2 GNB1 OR5V1 OR2T27 RGSL1 FZD4 HBEGF HRH3 PTPN6 RTKN PLCG1 EVC2 GUCA1A TNFRSF10A AKR1C3 GNAQ CCL25 OR51E2 SMC3 KLHL12 ARHGAP32 OR2L2 DKK4 PTGFR NOTCH1 KLB PDE6A CX3CR1 REEP6 CAMK4 TSHR HDAC2 OR9A2 ADH4 NAPEPLD OR6C68 OR52I2 DNM3 SLC38A9 IAPP IL2RB CENPE BAD TUBB4B FCER2 MAPK8 GAB1 OR1F2P ARHGEF15 CXCL9 NMT2 OR13C5 PARP1 CLPS HSD17B6 FLRT3 NRP2 NEDD8 MBD3 USP4 RASGEF1A NCKAP1 RTP1 PSMB10 PTPRO SGO1 GNA15 GTF2A2 OR4K14 COL24A1 HNRNPF PPARG ITGAV CDC42EP2 EIF4G1 WIPF1 OR6C2 FN1 NPS YBX1 NR5A2 OR51H1 NR4A1 TAS2R43 FPR2 ELF3 THBS4 PTPRA SOS2 OR2T10 CDC73 AATF CUL1 WDR19 CD55 FOXO3 TRRAP JUN OR4C46 IFT52 OR2AG1 ABR TNRC6B OR5M9 SFN MADD PPP1R12A POU2F1 RUNX1 KAT2B GPER1 GPIHBP1 ARHGAP20 MYH11 PRKAR1A HDAC1 MYLK IQGAP3 AVPR1B VAV1 OR51A4 OR2A25 KIF2C MTOR RTP3 TAX1BP3 RGR KIT ACTR2 ECE2 TUBA3E TULP3 GNB4 BMPR1A GRPR RHOH SFRP1 NOG OR10V1 MC4R OR5P3 MIB1 MAPK7 OR3A1 OR4N2 TNKS2 RHO TLE2 STAP2 OR4K2 RHOG NGEF DERL2 PSMB4 CCL4 BAG4 ADRA1B HIST1H2AD GPR65 TAAR5 OR2D3 DDX5 RPS6 CDC20 WNT3 CCR10 REEP4 AES HCAR3 SCTR OR4C6 OR5T2 AP2S1 FASLG DAB2IP RGS11 OR5C1 ARAP3 OR2AP1 PSMA1 RXFP1 CYP26C1 CDKN1A LAMB3 PRKAR1B CHRM4 RGS9 OR14J1 MAPK13 F11R PSME1 SOCS1 CTNNB1 GNAI2 GRIN2D RCC2 OR8S1 OR14L1P TNS4 GPR18 CTBP1 CHN2 ARHGAP27 RDH5 GREB1 OR1L8 GSK3A NR2E1 TACC3 IL5RA HIST2H2AC TAS2R13 VAV2 CHN1 OR1I1 TRH RRAGA PMCH PSMB8 BRS3 FFAR2 MC2R WNT3A LPAR1 IKZF1 CDK2 RBBP7 GPHA2 OR2T4 FRAT2 OR4D10 RTP4 ARHGEF19 PIK3R6 PDK1 VIPR2 ARHGEF3 ATP6V1C1 ARHGAP15 OR8I2 OR8K1 TUBA4A ADRA2A LAMB1 OR51B5 HEYL NCSTN CFL1 SOX4 POLR2H DGKI RTP2 DLGAP5 PPP2R1A OR5M1 NUP160 OR51F1 GNA14 RANGAP1 ARPC1A H2AFV PSMC4 CMKLR1 P2RY14 FFAR1 OR4Q2 FSHR OR2T5 ARHGEF9 WNT7A ADRA2C ARAP1 GNAL DTX1 DRD4 CDK8 OR2T8 DLG4 DAGLB NOXA1 OR4B1 MAD2L1 SKI RHOB OR5M8 GRM5 OR5D14 STAM GRIN2A EIF4B HIST1H2BM CTNNA1 PDE1B CCR2 OPN4 AGTR1 PSMD8 SIRT6 LAMTOR5 OR1F1 DNM1 SPC24 WDR83 INHBB APLN OR10D3 RDH14 TGIF2 PDHB PSMD14 OR5AP2 OR13A1 WNT2B GPR35 IRS2 CRHR1 NCK1 NEDD4L MAPKAPK2 SMAD6 BTC METAP2 CASP9 PORCN OR10A6 TNFSF10 RPE65 MYD88 PYGO1 IL2RA ERBB3 ARHGEF40 PRKCB DSN1 LGR5 RASGRP3 CASP8 HIST1H2BL ESRP1 OPN1LW GPR55 PSMC5 CGN GCGR WNT5B ZFYVE16 GPR25 RAC3 GPR15 HIST1H2AJ RARB E2F1 ARHGEF11 POLR2E CXCL1 MAPRE1 VEGFA TAS2R3 NMUR1 OR6C75 GPR83 GAST CFTR YWHAH OR11H4 ECE1 RASAL2 FGF8 RHOJ SMURF2 PPP3CC PREX2 FGF23 COL1A2 OR4S1 OR6A2 PDGFRA FES SST FSTL1 PDE4A ASH2L INHBA CCNT1 STRADB HSD17B1 OR52A1 OR5D13 CCL21 NSMAF OR51M1 OR1D2 HGFAC OR2V2 TAS2R60 SH3KBP1 PDE6B CRHBP ARHGAP31 OR5M10 OR2F2 SPRED2 COL11A2 FZD9 CRHR2 P2RY12 ARHGDIA GHRHR NCOA2 OR2AE1 SUZ12 ADCYAP1R1 HES5 OR8B12 GZMB SMARCA4 CMA1 FLNA TRADD OR2G2 OFD1 AGO3 APOM OR5D16 MAF1 HCRTR1
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Hierarchy Landscape

The following plot represents the hierarchical landscape of 'Signal Transduction'. The hierarchical tree allows to click on the pathways with children (black border) and continue the exploration. All nodes are colored by their source (click on the map for the legend) and cross-link to the original pathway page.

Sub-Pathways

About

ComPath is developed and maintained in an academic capacity by Daniel Domingo-Fernández and Charles Tapley Hoyt at the Fraunhofer SCAI Department of Bioinformatics. This web application relies on data loaded from KEGG, Reactome, and WikiPathways Restful APIs, as well as MSigDB. More information here.