Signal Transduction - Pathway Page
Name Signal Transduction
Resource Reactome
Genes OR2W6P CDK5R1 RET PTPRJ POMC CDC20 BUB1 OR5M10 H2AFB1 PDE8A PLPPR5 PPP3CA OR4A8 KEL UCN PSEN2 DTX1 LTB4R DKK2 SMAD5 FZD10 AES AGT AP2M1 HCRT FFAR3 CKAP5 CYP26C1 RNF111 OTULIN APP VEGFB PSMB9 OR2T1 ESRP2 PIP5K1B OR5D13 SRGAP3 ACKR4 PDE1A RHOU ADH1A FGF3 AP2S1 PLA2G4A ADRA1A CCNT1 H2AFV OR52A4P ITGB1 OR13C2 CHUK FABP7 OR5AK3P DNAL4 SH2B3 DLK1 FADD GPR18 ARPC1A GPER1 RDH13 TRIM27 GPR68 REEP6 MOB1A RAF1 GRAP2 DHRS9 RANBP10 FUZ OR5AU1 CBX8 CNKSR2 FURIN MAP3K7 SH3GL2 SOX6 OR6B3 OR5K2 FMNL2 CD19 CAV1 SOCS1 OR7A17 KDM4C S1PR1 XCR1 OR10A4 CCRL2 OR4A15 USF1 PARD3 ACVR1B CASP10 PRDM4 ADRB2 OR8K5 AGO1 PML IFT140 IGF2BP1 OR4F6 HHIP ADCY8 MOV10 UCN2 CDH5 PSMB10 OR4K14 GATA3 GRM8 RGS6 AVPR1A TACR1 ABCA4 HIST1H2BN OR14I1 HIST2H2AA3 OR10J1 NUDC OR6C68 ADORA1 CCL25 FN1 HRH1 BCL9L BMP2 EDN3 OR5T1 PSMB4 POLR2D ARHGAP10 NOX3 IFT52 ACVR2A GTF2F2 CYFIP2 MFNG OR1F12 NPS ASH2L TFDP2 UTS2 ADRA1B PMF1 NDEL1 NUP107 TAS2R30 NTRK2 ATP6V1B2 OR5AC2 TUBB3 OR1K1 RAPGEF3 PSMC3 LAMTOR4 GNG12 KANK1 E2F1 DGKZ AKR1B10 PDE7A OR5P3 ADRA2B PLEKHG2 TAS2R40 GALNT3 PTPN12 VPS26A FNTA CHD4 OR51Q1 PTPRA ECE1 TSC2 NCOR2 ARHGDIG ZFYVE16 C3 NOS3 NRG2 RGS21 ARHGAP33 ITGA2 HIST1H2BD OR6M1 CIT YY1 OR8B2 TUBA1A IL1RAP CCL20 CDC25C TTR OR10G4 KLC4 OR51I1 NEDD4 PSMB3 TSHB PLCB2 FOXA1 PIK3R5 PROK1 GPR39 GRB10 PTCRA SERPINE1 USF2 OR10K1 COL11A1 DLGAP5 OR2T2 OR52R1 ST3GAL3 OR6C75 OR7D4 TGFB1 CXCR5 LPL CDK4 OR10X1 PRKAB1 CCR6 SFRP2 TAS2R31 FFAR1 RSPO2 CHD8 OR8I2 IGF2 OR2A4 OR51G1 BOC MAP2K1 NRAS DYNC1I1 RBBP7 TAS2R38 OR2V2 CSNK1E OR2T27 SMAD2 BTC NCF4 PTH2R SYK LHB OR3A3 TULP3 FLRT3 LPAR1 IFT172 CYBA RBP4 PDPK1 SOS2 SPINT2 DGKA IAPP WIPF3 YWHAZ GPR143 DUSP4 GNB2 ARHGAP12 NEFL PLPPR3 KIF3A PDE1C CDKN1B RCOR1 KREMEN1 IL3 CAB39 AKR1C4 GNG11 OR2Y1 RIPK1 FGF1 OR52Z1 MAPK13 ATP2A2 CENPP DOK1 GRK3 GNAI2 THBS3 OR4S1 RAG2 OR2W5 OR2H1 RPS6KA3 PDE8B OR52N5 OPN3 OR52I1 OXER1 ARAP2 GPHB5 ELF3 KIT TFDP1 XIAP TAX1BP1 TUBB2B PSMD4 DLL1 HRH3 WNT2B SEH1L APOC3 OR10J6P FGFR2 TGFA TMED2 RGS18 HDAC9 AATF HDAC10 TJP2 RPS6KA2 AGTR2 ARHGAP36 OR10J4 REEP4 CDC42EP5 RTP5 OR5B21 CXCL10 HIST1H2BC GNRH2 AHCYL1 OR5AK2 UCN3 GPR17 FGF8 PDE4A OR4A47 BEX3 PDYN PRKAR1B OR51E2 OR4D10 APOA4 ARHGAP27 GPR45 OR10A5 TLN1 CUL3 FGD2 P2RY1 OR51B2 OR5K1 OR2F1 PSMA7 OR4C46 SHARPIN OR10W1 OR5B17 STRADA GPR37 STAT1 MYO9A TRAF2 OR11H7 CILP CALM1 INSL3 DYNC1LI1 PPP2CB ARHGAP9 IGF1 RALBP1 UBE2D3 CXXC5 RNF31 PPP1R1B RGS13 CDC42 PHB COL24A1 OR10R2 OR1E3 GLI3 DRD1 RGS8 CTSD LAMTOR5 KDR CAMK2D OR4K5 ZWILCH CYP26B1 MCHR2 HDAC11 FGB KIF2B P2RY4 UBB PSMD10 PSMD3 OR52E2 ESR1 CXCR4 OR2T11 NUP98 GPC3 PRKAR2A OR51E1 DAGLA OR2V1 RAPGEF2 FRAT1 OR4F5 PTPRO APLNR PDE3A HTR2B SMURF2 CDK2 NOXO1 RPS6KB1 RAPGEF4 RASGRP1 PRKAB2 AXL GPRC6A GZMB GRM3 OR8G2P SGO1 BAD LAMB1 ARHGAP39 INSL5 PDE4B COL1A2 CCL5 PRKAR1A ARHGEF19 PDHA1 CSF2RB OR10H4 STRA6 ARHGDIA OR4F16 OR1E1 PYY TGIF2 ADGRE3 IRAK1 OR10D4P NMT1 OR11H6 OR5AN1 OR51B5 PSEN1 PTGER1 VAV3 OR10A3 STAT6 PRKAA1 WNT9A DOCK1 OR2T29 NEURL1 OR3A1 RAMP1 GPR132 ARHGAP19 POLR2G FNTB DISP2 ERLEC1 ARHGEF25 ATP6V1D CRHR2 IL6ST PCSK5 AKAP9 OR5D14 RXRB OR2G3 PHC2 OR52W1 GFRA1 CENPC GUCA1A OR51G2 HDAC7 CFL1 HEY1 CASP8 RBP2 PSMB8 GHRL PDGFD ITSN1 CCNK OR4D6 FGF22 CXCL8 ARHGAP25 DNM1 ARPC5 MLST8 SPRED2 HGFAC OR5J2 RXFP3 OR7A10 NOTUM MAPRE1 HEYL HBEGF RBP3 MRTFA USP4 PTGDR2 CD55 ADCY5 OR5M1 MC3R RXFP4 THBS2 RANBP9 EP300 SHC3 FZD8 ST3GAL4 NCK1 ITPR1 GALR2 OR13C5 MTA1 PELP1 HSD17B6 NPW OR1E2 RGS17 GNRHR2 RBBP4 CSN2 OR13C3 AKT1 PPP2R5E SEL1L FSTL1 GNAI1 OR2S2 OR2B11 CYBB USP7 BAX OR51A2 IKBKG OR5A2 PSENEN OR5G3 CENPO SSTR4 OR10G6 OR5H6 RDH14 GNB1 PLK1 BCO2 MAGED1 NGF PDGFA ITGAV HSP90AA1 OR6C74 OR9G4 ACVR2B LIMK2 OR7A5 OR51A7 ALDH1A1 DUSP6 PTAFR XCL2 ATP6V0C SPRED3 PDE6G YES1 MAPK12 KL PPP2R1A INHBB TACC3 ADGRE1 KLC1 KSR1 KCTD6 PIK3CD LTB4R2 PSME4 SAG FRK WASF1 NUP133 SPTBN4 CTTN NUMB MIS12 OR51T1 POGLUT1 CHRM1 DUSP7 RGS2 MYH11 PDE10A IL5RA GSK3A PMEPA1 GPSM1 OR10K2 MAP3K11 F2R CHRM2 OR6V1 CBL MAP2K2 HCRTR1 SPC25 PLPPR4 ULK3 RALGDS CTBP2 OR52K2 GPC5 CTNND1 DERL2 CCL13 GRM4 FGF2 OR52I2 GNB5 REEP3 CHRM3 MIB2 RALB COL3A1 RNF41 HCAR1 SKA2 OR14A16 MEF2A ARHGDIB OR5C1 ADCYAP1 OR6J1 GRIN2C SOX17 HSD17B1 GUCY2F AXIN1 FLT3 DLG4 PRMT1 CDK9 PTPN11 MLN SRMS RGR PIK3CA SSTR5 MCF2L RGS16 PNLIP TJP1 TNFRSF10A DGKH PDGFRA TFF3 RTKN WNT10B DYNC1H1 GFRA4 DIAPH1 GAL QRFPR AVP POLR2F FLT3LG BCL2L11 UBC ARTN GSK3B OR8U8 RPS6 PAK2 PROKR2 SDR16C5 VEGFA P2RY14 LPAR3 PPP2R5C PSMC1 EIF4E ABI2 KNG1 TMED5 NUP160 ATP6V1C1 USP9X ARHGAP29 RHOG ATP6V0D1 OR1C1 PTGFR ARHGAP28 DNM3 PPP1R14A REEP2 RSPO4 AKAP13 COL2A1 NR2E1 RHOQ GGA3 EDN1 THBS4 OR14K1 POLR2H ARHGAP17 DUSP8 OR2L2 HTR1E SMAD3 OR6N1 NCAM1 OR5M8 CSF2RA OR5H14 OR2I1P OR10H5 SPTBN2 B9D2 RSPO3 FGF10 WNT9B CXCL13 NDE1 ADCY3 OR13C4 JAG2 HTR2C TUBA3E NCKIPSD CARM1 OR4C16 CLASP1 GUCA1C APBB1IP APOE H2AFZ RASGRP4 ADRB1 CYSLTR1 WASF2 HDAC3 ARPC2 NTS CALCA DRD3 OR51H1 XPO1 OR56A3 RLN2 ATP6V1G3 CDC14A OR10C1 ACTA2 PDE11A WWOX DUSP10 MAD1L1 GLP2R PRKAG1 KLC3 STRADB LRRK2 ZWINT CDK1 ZW10 CCL16 GPBAR1 HDAC5 CCR3 OR8G5 LRAT TSC1 ARHGAP20 TBL1XR1 ATP6V0E1 NEDD8 OR52B6 ARHGEF40 DIAPH2 GRM2 GNA15 OR7G3 OR4Q3 KSR2 CENPE HIST2H4A IRS4 TAS2R5 INPP5B LGR5 OR1F2P GNAI3 NELFB MOB1B GALR3 ABL1 OR5H2 FGFBP2 STAT5A NLN COL11A2 BDNF RARB TTC21B EPS15L1 FGA PENK RLBP1 MST1 PIK3R1 GPR31 STAM2 RARA VEGFD DKK4 CDCA8 ARF6 TRPC3 CYSLTR2 CENPH GPC2 ATP6V1H NRP2 F2RL2 ADORA3 OR4E2 PSMC4 PAFAH1B1 PPP3R1 PDE1B OR8K1 YWHAB WNT7B OR6S1 KAT2B WIPF2 TAGAP CNR1 LFNG WNT3A OR2A14 IL1RL1 S100B GNG5 PXN ADORA2A SPDL1 RASGRP3 MCF2 RPTOR LEF1 E2F3 ITGB3 XCL1 SKIL MYL12B NRTN PAK1 APLN KMT2D OR1P1 CRABP1 PRKCI OR51I2 ITPR2 MST1R GNG13 SMAD4 OR2AT4 RHOT2 PDHB PSME3 FZD1 INSR SPTBN5 PDE4D KRAS LHCGR ARHGAP6 OR51L1 RDH8 OR52E5 RBPJ RXFP1 DGKE MIB1 TRAT1 MGLL NMBR PTGER3 ADAM17 GPR83 PIP5K1A SSTR2 TAS2R10 TAAR3P RGS1 OR52N4 RRAGC SPTB PREX2 OR8D1 MYH14 OR8K3 TSHR MAG OTUD3 VCP RRAGD WWP2 OR4N2 OR56B2P NPY CHD1 FFAR4 ARHGEF5 HNRNPH1 PDHX B4GALT1 TNKS2 OR2L5 KIF2C PTGER2 DUSP5 SALL4 MAPKAP1 LRP5 RPS6KA1 PRKACA TAB2 HIST1H2BM ATP6V0A2 PPP2R5D RDH5 STARD8 OR56A4 TBL1X MYO9B IHH BDKRB1 HIST1H2AC KPNA2 E2F5 UCHL5 RETSAT LATS1 TNS3 TGIF1 OS9 ALDH1A2 ADRA2A PHLPP2 RAP1B PIK3C3 VIPR1 RRAGB OR5B12 OR2G6 MET ATP6V1E1 CENPT POLR2K HPN NPY5R EFCAB7 ADORA2B NTF3 RASAL3 ROPN1 OR2D2 GNAT3 IKZF1 REEP5 MAMLD1 PSMB1 CPT1B SOX3 FRS3 OR4C13 CDC73 LAMA2 OR52E1 NFATC1 CDH1 OR5M11 TRH PFN1 LAMTOR2 IQGAP1 OR7A2P OR51B6 SNAI2 RASA2 AKR1C3 GPC6 PMCH MEN1 FYN SST F2 OR10G8 NEDD4L OR52M1 SDR9C7 ERCC6L NCF1 OR2K2 PHLPP1 NCOA3 NFKBIA CRKL NDC80 OR11H4 GPR4 SPINT1 SHC1 ADCYAP1R1 CX3CL1 GNAT1 KISS1R YWHAE OR52E6 S1PR2 QRFP GREB1 OR4M2 TUBA8 OR5AC1 PTK6 OR7C2 KIF18A OR5H15 CHD3 HIST1H2BO MYL9 GHRH CBX4 PDK3 DYNC1I2 CCL27 HNRNPM POU2F1 PPP3CB NGFR FST ARHGAP23 HIST1H2AD CCR10 DNER FOS OR10A6 BIRC2 PPP1R12A RNF146 HIST1H2BJ SPP1 PPID OR5K3 KIF2A MUC20 MYC OR2AG1 TFF1 CCL28 RHO PKN2 ZNRF3 KISS1 OR10AD1 IL2RG PDE2A SOX4 CYFIP1 AURKB SOX2 KITLG OR2M2 OR4K2 OR10D3 OR1B1 HIST2H2AC RASAL1 OR8H2 JUP SPTBN1 OR8U9 CCR5 RCC2 ARHGEF15 STAG2 AKR1C1 ABI1 YBX1 OR9A4 PGR GNRH1 GTF2A2 CDC42EP3 OR10J3 PIP4K2B KBTBD7 CXCL16 PPP2CA NFKB1 OR6C76 ANGPT1 RTP1 GPC4 KLC2 OR2W1 PSME2 ARHGAP42 GRM5 ADAM12 CTNNB1 VPS35 TACR3 RBX1 OR7D2 PLCB4 PORCN ARPC4 OR1S2 PPP1CA RAC2 HNRNPA1 FPR2 FGG MYO7A PSMA8 OR5AL1 CNTN1 SSTR1 FZD5 TAS2R7 OR52N1 JAK3 OR4F15 WNT2 PRKCD SPRY2 OPRM1 KHDRBS2 SKP1 DUSP2 OR10G2 OR2T12 TIAM2 CXCL5 OR1Q1 PRKG2 STAM PDGFC PPP3CC FAM13B ARHGAP26 OR2T3 PTPN3 RBBP5 UTS2R TBP OR5H1 MCHR1 OR51V1 PDGFB S1PR4 CCR7 OR52J3 FMNL3 OR6Q1 GPSM2 PRKCE OR1S1 POLR2C OR4B1 MAP2K5 TLR9 PAG1 DGKG ARHGAP40 OR4K1 NOTCH3 GNAQ OPN1SW DIAPH3 PTPRS TAS2R20 OR56B4 HIST3H2BB OR10G9 COL4A3 EDNRA GNGT2 RRH OR5M9 TUBA4B LDLR F11R OR52L2P PTGER4 PIK3CG OR1M1 WWP1 FES RUNX1 H2BFS GLI2 OR2J1 HIST1H2BA LPAR5 APH1A RGS9BP A2M CD80 CBX2 SMPD3 RSPO1 CREBBP ACKR3 EGR1 OR14C36 EVC OR10H2 OR2AP1 CXCL12 NCOA2 PRC1 SUZ12 OR52D1 CDC14B GPR65 OR11H2 OR2T6 SMC1A FPR1 COL9A3 LAMA3 TAB1 TUBB4A HGF ATP6V0A4 TAS2R8 OR6K3 OR5V1 NRIP1 TAS2R45 GLP1R RANGAP1 CCKBR AGTR1 PRKCG PREX1 TIAL1 GPR176 ARHGAP5 HRH2 PRKAA2 OR3A4P HTR4 RGS20 OR51D1 ARHGAP15 NPFFR2 TAAR5 TNFSF10 OR52H1 RGS14 NTSR2 OR5T2 WIF1 AXIN2 TYK2 OR13G1 MC4R TAS2R60 LGR4 HNRNPF NUP43 OR13D1 RCVRN GNA13 PRLHR CASR TLE2 NCK2 COL4A5 RAB6A DVL3 FCER2 DGKI OR4Q2 OR6C2 ALDH8A1 CSNK2A1 TNKS OR10AC1 PYGO1 WASL OR4K17 TNFRSF10D HIF1A DNM2 OR51M1 DHRS4 OPHN1 CCK PHC3 NR3C1 GRK1 CCL23 OR6B2 PTGDR LPAR6 NOG APH1B EDN2 TAS2R4 OR4K15 SMAD7 WNT5B TNRC6C DRD4 NSL1 EZH2 DSN1 CLTC RHEB RIT2 ARHGEF10 TUBB6 CNKSR1 OR5A1 OFD1 FSHB HECW1 PTPN2 ARAP3 GNA12 MADD GIPR PDK2 POLR2B ANOS1 APOM OR2T7 SMAD9 NOTCH1 ADM2 GRP OR9G1 AKT1S1 MMP9 OR2W3 SRGAP2 OR10Q1 TAX1BP3 CALCB CXXC4 OR1D4 PRR5 TUBA4A PYGO2 PSMD7 TAS2R43 IL6R PDE6A DNAJB1 PIK3R3 WNT8B ITGA3 OR52P1P GRM6 MAML1 STAT3 E2F4 FER ABR HIST3H3 ATP6V0E2 SLC38A9 OR8S1 OR8B12 GNA14 SRGAP1 FGF6 LAMTOR3 RBP1 TRPC7 TAS2R19 OR6A2 PROKR1 USP34 GDI1 SH2D2A ESR2 EGF YWHAG MYB GRM1 MKS1 OR4E1 IFT88 SPRY1 RAPGEF1 TRADD GPR84 SYVN1 PDHA2 GPR25 GUCY2D ATP6V1E2 C3AR1 ERBIN TAS2R41 PRKG1 GPR20 RGS10 NOTCH4 LRP1 OR6C6 APC GPSM3 TNS4 DTX2 TCF7 SCMH1 OR1L8 OMG MAD2L1 HTR2A CNGB1 MYL6 CD86 OR5D18 OR13C9 CXCL3 ERBB4 GALR1 GTF2A1 OR10H3 DGKD NMUR1 NCOR1 TRHR PSMD9 GNA11 OR10Z1 OR10G3 OR6X1 MYLK PEA15 RGS5 PSMD1 RAMP2 KALRN AGRN IL17RD OR4C11 BMI1 ALDH1A3 ARHGAP22 RUVBL1 PDGFRB ARHGEF7 OR1N1 OR2J3 SHC2 OR2M7 PROK2 TAS2R50 OR4D1 PSME1 ADRB3 ABHD12 LEO1 KLHL12 PSMB11 CSNK2B NCSTN ATP6V1A ARHGEF39 NMU CYLD NPSR1 NRG1 DAB2IP MKRN1 OR8J1 FGFBP3 PIK3CB SRY ADCY4 LAMB3 RBFOX2 PDE7B PTK2 SRC PTBP1 WNT11 BRS3 ARPC1B ECE2 RASAL2 CCR8 MAPKAPK2 FMNL1 MC2R WNT4 SMARCA4 RASA4 CAMK2G FSHR LATS2 PCSK6 ADCY7 WIPF1 SMURF1 PTCH2 PSMB7 PSAP TIA1 OR7E24 DAGLB OR2A12 VANGL2 HSP90AB1 GPR55 OR6C65 CRABP2 FKBP4 NMUR2 ITGA2B RGS12 PLXNB1 PDE3B THBS1 PSMB2 GRM7 OR4P4 MAPK3 OR8J2 APOA2 COL4A1 F2RL1 OR6C3 ESRP1 ROCK1 OR5F1 COL6A1 PPP1R15A OR10H1 CRHBP CHN1 TNRC6A TRIO ST3GAL6 OR1J1 GRIN2A PRKCB INCENP COL5A1 COL4A2 AVPR2 LRIG1 OR2H2 COL9A2 ADGRE5 PAQR3 CCNE1 RHPN2 TAC3 COL6A6 STK4 ADCY6 ITPR3 HDAC8 BMPR1B OR2G2 DRAP1 GNG7 GNB3 STAP2 OR8B4 NPFF ARHGAP11A ELMO2 GNG2 IQCE TAAR8 TEC PBX1 OR10V1 HTR1F YWHAQ ECT2 KHDRBS1 PTK2B PDK4 RHOBTB1 ARHGEF3 PLEKHG5 FGFR1 COL6A5 ADAM10 NRG3 MECOM ARHGEF6 DRD2 OPRD1 PTPRK ARHGEF26 RPS6KB2 GAB2 GAS1 CENPN TAS2R1 NF2 CHRM4 MAPK1 SMO ARHGEF33 CORT APOB LIN7B GPR35 OR4F21 PLG GNG4 RHOD ETV4 JAK2 OR10A7 ERBB2 NUP85 S1PR3 EGFR MDM2 HIST1H2AB AR WDR19 FGF16 PLCG1 GATAD2A PLB1 PPBP TAS1R1 RHOJ SHH PSMD12 POFUT1 GAS8 DOCK7 PIK3R4 TAS2R3 RBL1 HRH4 OR51J1 LAMTOR1 SOS1 GNAL FABP5 SKI CYP26A1 OR8D2 OR11H1 OR51F1 FGFRL1 OR1L6 CBX6 CSF2 DUSP3 RACGAP1 WNT16 ARAF ARHGAP1 AHCTF1 OR8G1 PIK3R6 GRK4 SP1 GFRA3 USP8 JUND KDM4B AKT2 POLR2E KAT5 WASF3 SAV1 RANBP2 ADCY9 OR5W2 GRK7 CAB39L CXCL2 CBY1 OR2AK2 OR52B2 OR13A1 DVL2 VIPR2 PLPPR1 BRK1 OR10AG1 PRKCZ OR13C8 TNFRSF1A CCR2 PSMF1 GMIP PPP5C COL27A1 VIP ACVR1C RGSL1 WNT3 CCL4L1 PTGIR EPAS1 CHRDL1 GPIHBP1 CENPU OR5I1 TRPC6 OR9G9 LRP8 P2RY10 DUSP1 EDNRB REST FGF9 PTH ARHGEF38 OR4M1 OR2M5 ADGRE2 FRAT2 HCRTR2 OR6K2 OR1D2 OR13J1 TRIM33 CENPM LAMB2 PGF CLTB BIRC3 NUF2 SUFU P2RY11 ACTR2 OR5AR1 GPC1 RALA COL4A4 GRIN2B OR8A1 GRB2 BMP10 PPP1CB FGF4 OR5L2 RHOV MTA2 LGR6 LAMC1 GOPC OR56B1 HIST1H2BK KIDINS220 KAT2A PPARD RPGRIP1L HIST1H2BL GDI2 DDX5 HCAR3 PSMD2 DYNC2H1 CLASP2 USP13 PSPN DYNC1LI2 TACR2 ATF2 SDC3 CDON PDE6B FAM13A TLE3 NET1 IGF1R SYDE1 SPPL2B OR2B3 MATK PTH2 TUBB2A ARRB1 OR4N5 OR1A1 ARHGEF9 RXRG RHOC RXRA STARD13 GFAP EED USP15 CD28 WNT6 RDH16 SDC1 FZD7 NEURL1B CSNK1G2 ARHGEF37 SFN DYNLL1 FLT1 FGF23 IKBKB SFRP1 FKBP5 SPHK1 OR8J3 HDAC6 OR1A2 AVPR1B MLNR RASGRF1 NPBWR2 PSMA4 CCND3 FSTL3 ARHGAP31 ACTG1 TERT FGD1 ARHGEF2 IL6 DOCK3 RLN3 MYH10 OPN1LW SMAD6 PAK3 CASP2 HTR1B GNB4 BRAF F2RL3 OR4F17 CCNC HTR6 THEM4 FGF5 TAC1 SHB YAP1 OR52E8 RPS6KA5 PRKACG DTX4 RUNX3 CLPS PDE4C SOCS6 ATP6V0A1 PPM1A OR2A42 OR2A5 HIST2H3D TNFAIP3 BCR NTRK3 PSMA6 UBA52 PIK3AP1 OR4K13 GTF2F1 AGO2 GAB1 TUBB4B OR9Q1 RHOA GPNMB FZD6 NPY2R SRF CDC42EP2 GNAO1 H2AFX MAPK6 HIST1H3A CCKAR RACK1 ARHGAP8 GNGT1 TUBB8 BUB1B SOCS3 EREG OR5D16 KLB PSMC5 MMP3 TAS2R13 TUBA1B CENPS ADCY2 ATP6V1C2 DYNLL2 HDAC4 LAT HDAC1 LRP2 CALCR FPR3 ARHGEF1 OTUD7B MAF1 CCR9 WNT5A WWC1 MTNR1A FLT4 ARAP1 SPTA1 VAV1 LRP6 YWHAH CDC37 PTH1R GUCA1B PSMA2 ATP6V1G1 SLC24A1 TRAF6 PLCB1 PTPN1 DGKK OR10T2 LIMK1 CCDC88C GLI1 TLE1 ATP1B4 FGF17 POLR2J MTMR4 RIPK2 OR4X2 CLIP1 GNRHR VPS29 CLIP3 SEPT7 NAPEPLD OR6P1 PSMB6 OXTR DEPDC1B RRAGA CXCR1 OR4X1 STAT5B SMC3 OR2C3 GRIN1 FOXO3 EBAG9 OR2T34 S1PR5 METAP1 ATN1 RING1 RHOT1 RAD21 OR2J2 BIRC5 UTS2B EPN1 C5 CCL21 CSNK2A2 KNTC1 OR4C12 OXT OR7G2 RASA3 PTEN OR2B8P ARHGAP35 GPR27 ARHGEF4 OR51B4 CXCR3 RGS7 GABBR2 NRP1 CHN2 PHC1 CDKN1A GPAM OR52A1 TCF7L2 CALCRL OR2T4 ACKR1 CTBP1 AMHR2 OR8B8 SPC24 BMPR2 UBE2D1 TUBA1C POLR2A FGF18 P2RY6 NCKAP1L PIP4K2C ATP6V0D2 RTP4 OR51F2 KIF5B FAS OR1F1 RPS27A SH3KBP1 GRK2 KDM1A FGF20 INHBA RASGRF2 OPRK1 OR2L8 MYD88 SAA1 CCR4 FLNA MEMO1 ELMO1 RGS9 SUCNR1 GCGR PPARG DZIP1 HDAC2 STK3 CXCL1 PPP1R12B CLTA OR2T8 ROR2 ATP6V1B1 RHOF SOX13 GREM2 GFRA2 SEM1 SH3GL1 ACTR3 OR14L1P ATP2A3 WNT7A TBXA2R FZD9 CFLAR ADCY10 TAAR2 FOXH1 LYN APOC2 TAS1R3 OR1G1 OR4A4P NTRK1 RIT1 ADH4 ANXA1 DLL4 FOXO1 OR4N4 CXCR2 WWTR1 ROR1 ATP6AP1 SMPD2 RTP2 SPTAN1 IRS1 SYDE2 NPHP4 OR3A2 AKT3 NMB OR2AJ1 LAMC2 CCR1 RTN4 OPN5 OR6B1 OR2M3 RHPN1 GPHA2 ARHGAP45 GPR37L1 MAPK14 ARHGAP32 ARHGAP24 OR51S1 OR14A2 IER3 SNX3 PLPPR2 GRK6 SPPL2A PNOC AGO4 CTNNBIP1 RGS22 CYP4V2 OR9A1P GPR15 NCBP2 OR5K4 CGN DRD5 BAIAP2 EIF4G1 PKN1 CDKN2B PTCH1 VWF OR6C1 SCT PARP1 OR5B3 SYNGAP1 CAMK2A PSMB5 OR13H1 CHRM5 GNAZ ZFYVE9 DUSP16 SCUBE2 MAPK4 ERBB3 PRKCQ P2RY13 LPAR2 DVL1 OR6C4 OR11L1 ADM OR7G1 HTR1A OR6Y1 CREB1 OR4D11 RHOH MAPK8 POLR2L RAB4B STK11 ARPC3 MC5R OR10A2 TRIP10 IRAK4 PSMA5 ARHGEF11 PPP2R5A OR5AP2 MAML2 HSPB1 FLRT1 ABHD6 DACT1 PRKAG2 DLD CASP3 PPP1CC MAPKAPK5 INTU OBSCN TAS2R16 MED1 LAMA4 KHDRBS3 NCOA1 MAML3 GPR32 IL5 CXCL9 APOA1 CRK OR2AG2 OR9A2 TAAR1 RGS19 ARHGAP44 PTGES3 OR2F2 PLAT PSMD5 P4HB NGEF RICTOR OR51A4 STAG1 VRK3 FGFR3 OR6K6 CER1 IL2RA CAMK2B GABBR1 CCL19 AP2A2 REEP1 DGKB RDH10 IFT122 GNG10 TAS2R46 NPB CENPF HTR1D MAPK11 KIF14 DLC1 DLAT ADH1C OR1L3 BTK GIP ARHGAP30 PCP2 NPFFR1 MYH9 EPS15 FOXO4 SOX7 OR6N2 COL6A3 FGF7 NPY4R LEP VEGFC OR2C1 OR2AE1 CCL4 BMPR1A HEY2 COL5A3 BCL2 NR4A1 C5AR1 HIST1H2BB JUN ACTN2 HRAS OR2Z1 LAMC3 SPOP OR4F4 WLS SOX9 TCIRG1 NOTCH2 OR1N2 OR10G7 EVC2 ITGB3BP CCNT2 SNAI1 NUP37 SDC4 CGA INS CSK PSMD14 CDK8 GRAP IL33 H3F3A OR2A25 IRS2 EIF4EBP1 TAOK1 OR4C45 PRICKLE1 NCKAP1 RELA PFN2 RNF2 ROCK2 CENPK KNL1 TAS1R2 GHRHR OR52K1 DGKQ OR5P2 PRKACB AMOT FZD3 NMT2 SFPQ ATP6V1F ADRA1D PSMA1 CMA1 NPY1R LINGO1 ATP2A1 NF1 NR5A2 GNAT2 CAMK4 RAG1 CENPA RASGRP2 OR2D3 IFT57 AMER1 HES1 OR4A16 OR4S2 CCND1 P2RY2 ARHGEF35 FKBP1A TRIB3 HTR7 OR52N2 CENPI SIRT6 FOSB OR2B2 NMS DKK1 MT-RNR2 OR2T5 OR5AS1 TAS2R9 OR1J4 IQGAP2 OPN1MW CNR2 MARK3 OR5T3 HIST1H2AJ KTN1 EIF4B CITED1 OR1L1 TP53 BTRC ARHGAP4 SEC13 FBXW7 AP2A1 AGO3 HGS GHSR WDR83 OR8H3 PSMD8 PIK3R2 FGFBP1 OR9K2 PSMD6 PEBP1 WAS PDK1 IL3RA OR8H1 CXCL11 OR12D2 BDKRB2 ARHGAP21 GRB7 FASLG OR52A5 MC1R OR1L4 RAMP3 OR5B2 RTP3 WNT10A OCRL TEK SH3GL3 OR8U1 RHOB PRLH TUBAL3 CENPQ DHH KLK2 PSMD13 BRAP ARHGEF18 RBCK1 OR12D3 AWAT2 PSMD11 OR13F1 EVL PPY RDH12 COL9A1 PRKAG3 OR4D2 NRG4 FGFR4 CPT1A RAP1A SNW1 CX3CR1 ZNF217 OR2T33 MKNK1 GRK5 PRKAR2B OR4D9 NSMAF HHAT PLXND1 OR4A5 TNF RXFP2 PPEF1 GPR183 ELK1 ITCH SCAI FZD2 AP2B1 ATP6V1G2 PARD6A RGS11 WNT8A PPP2R1B MBD3 OR1D5 OR5L1 GAST CUL5 NLK LCK HES5 METAP2 ADRA2C LPAR4 PIP4K2A TGFBR1 ACTB RGS3 RAC1 FZD4 CXCL6 MTOR OR14J1 OR52L1 FFAR2 SKA1 PPP2R5B OR4K3 HIST2H2BE TNRC6B POLR2I COL5A2 NTF4 OR52E4 TNFRSF10B PLCB3 SSTR3 OR2A2 RASA1 OR4C6 PTPN18 ARHGAP18 OR2L13 CXCR6 AMH PSMA3 FLRT2 ARRB2 OR2T10 KIF7 OR7C1 SCRIB CBFB OR10S1 LAMA1 OR9I1 OR10J5 JAK1 OR56A1 OR8D4 CNGA1 OR11A1 MAPKAPK3 OR6T1 TRAF1 RHOBTB2 H2AFJ MAPK7 BAG4 SPRED1 OR10P1 XK SH2B1 GNAS PF4 TAS2R39 FRS2 OR4L1 DUSP9 PTHLH GRIN2D PKN3 BCO1 RYK OR2A7 GDF2 ACVRL1 COL6A2 VAV2 OR56A5 JAG1 DHRS3 GPR161 CTNNA1 OR2B6 NCBP1 TCF7L1 USP2 KLK3 FGF19 KREMEN2 CMKLR1 TAB3 OR4C3 PSMC6 LRP12 OPN4 BCL9 GPR150 NPBWR1 IQGAP3 SMAD1 HEBP1 CRHR1 OR9Q2 MTA3 JUNB GCG OR4D5 RNF43 GATAD2B ARHGEF10L CDK5 OR2M4 VCL OR2L3 KIF5A UBE2M WNT1 CSNK1A1 GNG8 CRH RFNG MEF2C OR5M3 STRAP HCAR2 ADCY1 NOX1 EEF2K ARHGEF12 RAB4A GNG3 IL2 HTR5A TAAR9 CENPL RDH11 TLE4 RASGEF1A GRPR OR1J2 TAS2R14 FGD4 RPE65 PRKCH AMOTL2 C5AR2 AMOTL1 COL1A1 TAS2R42 DAAM1 TGFBR2 OR1I1 SOST RAC3 OPRL1 HIST1H2BH PSMC2 OXGR1 PTPRU WDR35 SDC2 ATP6V0B HSPG2 PTPN6 ICOS NCF2 USP21 DEPDC7 SQSTM1 ARHGEF17 OR4C15 OR6F1 OR8B3 TAAR6 OR4C5 ATF1 NTSR1 GDNF NOXA1 BUB3 SGO2 CHEK1 RARG LEPR P2RY12 SH2B2 TUBB1 CFTR MTNR1B CUL1 BAMBI OR2T35 OR6C70 CCL1 FGD3 ARHGEF16 STUB1 LRP10 ARHGAP11B SPOPL RTN4R OR11G2 PRKCA SCTR LAMA5 BCAR1 TRRAP TIAM1 PIP5K1C OR5R1 CASP9 RPS27 CAMKMT RGS4 MDK IL2RB
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Hierarchy Landscape

The following plot represents the hierarchical landscape of 'Signal Transduction'. The hierarchical tree allows to click on the pathways with children (black border) and continue the exploration. All nodes are colored by their source (click on the map for the legend) and cross-link to the original pathway page.

Sub-Pathways

About

ComPath is developed and maintained in an academic capacity by Daniel Domingo-Fernández and Charles Tapley Hoyt at the Fraunhofer SCAI Department of Bioinformatics. This web application relies on data loaded from KEGG, Reactome, and WikiPathways Restful APIs, as well as MSigDB. More information here.