Signal Transduction - Pathway Page
Name Signal Transduction
Resource Reactome
Genes TRIM33 PTPRS LRP12 SH3KBP1 NPY5R ARPC2 P2RY2 PPP3CA GDI2 NCKIPSD BCL9L MC4R SOS2 CHD3 OR4A15 KIF14 RSPO1 PROK2 PLCB1 OR1D2 TACR1 OR14K1 MYB AKT1S1 RTP3 OR4E2 OR6C70 WASF3 EDNRB OR2A5 PIP4K2A PTK6 OR52M1 ACVR2A UBB OR51I2 TAB3 CYFIP1 CDC73 OR5J2 VEGFA OR8H2 CCL19 PPP1R15A SIRT6 PIP5K1B DUSP8 AKAP9 OXGR1 GPR161 OR2B6 GPR84 PDGFRA TNRC6B IL3 OR5B21 SCUBE2 NDE1 RAC3 NAPEPLD CXCR1 ARHGAP19 GNA14 CXCR2 GFRA1 NMT2 PDK4 POLR2C RRH NSL1 FGF3 FGFBP3 RUNX1 OR51A2 OR13A1 NPS PSME2 CDK5R1 OR5W2 COL6A6 OR8K3 GNG3 INHBA YAP1 TNS3 FFAR4 TTC21B OR8J2 CLASP1 GHRH OR9Q1 COL9A1 CAMK2A PDGFC OR5F1 F2R OR51B6 OPN1LW OR2T35 LIN7B PSME3 ADGRE2 KREMEN1 OR1I1 SFRP1 PPBP HTR6 CLTB NDC80 IKZF1 CTBP1 ATF2 OR2M5 OXER1 OR2T10 ARHGEF17 PPID RGS7 LAMB1 PRKCB PDE8B ATP6V1D NTSR1 SRGAP2 OR1N2 PDE11A MST1 HSP90AA1 TRAF6 EVC2 FLT1 CAMK2B SNAI2 PAQR3 USP15 PDK1 SRGAP1 TAS2R9 JAK3 USF1 SGO2 SUZ12 PTPN6 PAK1 UCN2 OR8K5 HDAC6 OR2A25 CCNT2 PRKCG B9D2 ADRB1 RYK MIB2 PDK2 OR2Z1 TJP2 HSD17B1 COL3A1 HCRTR1 VPS35 INHBB ARHGEF19 INSL5 CD28 RGS2 CENPI OR14I1 NCSTN PSMD13 PFN2 OR8S1 OR4D11 CFLAR DRD2 NSMAF PHLPP1 OTUD7B OR2AG2 TBL1X PORCN OR6S1 OR51S1 ARHGAP21 CCL25 GGA3 KSR1 SOX7 SKA1 NEDD4 OR52B2 RASAL1 PPP3CC GPAM GNG5 PSMB1 FER PIP5K1C JAK1 RBP4 LAMB3 EIF4B NCKAP1 OR52W1 MYH14 CXCL1 RANBP10 OR6C4 DTX1 HDAC2 NPFF FMNL3 GRK4 FGD4 PRKAR1B PARD3 PNOC ESR2 OR2A7 HIST1H2BN GATAD2A FST DOCK3 ADM2 YES1 OR2S2 GAL KLHL12 GNA15 ADRB3 PIP4K2C KIF2B ARHGAP39 LRP5 OR8K1 PDE3A NPY4R OR5AC2 FABP7 FLRT2 GPC2 FZD7 PSMB6 H2AFJ PPP2R5C OR51E2 SNW1 APOA2 OR52N2 MAP3K11 NCK1 TRPC6 MAPK3 GNAT1 FOXO4 OPN1SW CDK4 KLK3 GPR15 AVPR1B GHRHR RAF1 OR10G8 CDC14B CCR1 GPIHBP1 HEBP1 BTRC TSC2 NOTCH2 OR8B2 OR4M1 GAS1 GNA11 ARHGEF1 TRHR ESRP2 OR5D18 CCL21 OR11H7 FZD5 BIRC2 OR1L6 HDAC3 AHCTF1 AVPR1A TUBB2A CAMK2D GNG13 SRF PDE1C RSPO2 ROR1 FN1 PSME4 NMBR OR2T34 OR5K4 NCK2 H2AFB1 KISS1 TBXA2R RAB6A OR10A3 YWHAE UBE2D1 ADRA2B GNRH1 KAT5 SNX3 RTP1 HTR1B BOC AHCYL1 FGFR2 ARHGEF4 NEURL1 IFT57 OR56B2P CRHR2 OR6Y1 EIF4G1 HES1 NUP107 FKBP5 NPY OR56A3 NPHP4 OR5D13 OR51A7 LGR4 ADCY7 OR4F16 ADCY5 TFDP2 PDE4A WNT9A OR7A17 GNG7 DLGAP5 KLB USP2 MYO7A CENPE AKR1B10 PDE6A SKI CRHBP F2RL2 NOTCH1 FFAR2 PDE4B OR5B17 SDC4 USP4 OR10Z1 TNF WNT10A MTA2 IRAK1 ADORA3 INCENP CX3CL1 OR5H1 PTH ABR OR2A14 COL4A1 POLR2A EPS15 TUBB3 FGF17 CIT NUP133 AKAP13 SOX13 CRHR1 E2F4 IQCE PSPN DIAPH1 NRTN F11R KCTD6 SPRED2 OR10G6 HRH1 DYNC1I1 TMED2 TRPC7 RHOD PSMC5 SCTR E2F3 ST3GAL3 WLS CCND1 HES5 MYD88 ARPC4 MAP2K2 IL5RA ARHGAP6 RBPJ CSNK1G2 OR1E1 OR5D14 OR52E6 CENPF OR6B1 GNRHR2 FGF2 OR6C1 CASP9 NOX1 OR6C6 OR8G5 SOCS3 PLPPR5 PTGES3 CCL13 FGF5 STAG2 LINGO1 NTRK1 MLNR ADCY8 OR2G6 OR8I2 PLPPR4 ROCK2 FGFR4 PTCH2 RPS6KA5 CHN1 PROKR2 GPHA2 HIST3H2BB HIST2H4A GPR27 PRKCQ GNG10 ARHGAP31 OR52E2 OR8J3 OR4P4 CASR MAF1 HIST2H2BE MCHR2 ARPC3 MYO9A RASAL3 LAMA5 TAX1BP3 RRAGC IGF2 TAOK1 GPER1 BIRC5 NCBP1 RLBP1 OR52N1 PLEKHG5 GNAO1 TRAT1 RSPO3 MAPK8 MC3R RPTOR CENPL PDE4C ARHGAP45 LHB CYBB RGS1 FLT3LG DSN1 CAB39 PML OR4K14 ERLEC1 PDHX YY1 CBX8 TAS2R1 CAMK4 CHRM2 AGO2 PLB1 ARHGEF3 NF2 GPR68 DYNC1LI1 OR3A3 STRADA KL OR2B3 OR51H1 HIST1H2BB RACGAP1 SYDE1 LPAR1 ARTN USP13 GAB2 OR6J1 CGN AKR1C3 DUSP5 GPC6 GALR2 MTA3 NGEF ARPC1B SHARPIN JUP OR5K1 CITED1 RACK1 SPOPL RGSL1 OR10AC1 CDH5 PDE8A IGF1R SDC2 SQSTM1 PTH2 MAPKAPK5 RALA OR7A5 ROPN1 RTP4 PLA2G4A OR52I1 IFT172 PSMC3 PPY OR4M2 C5AR1 TAAR6 YWHAG GALNT3 PRR5 PLCB3 OR2M4 TAC3 TAS2R14 IFT122 PDE10A STRA6 CASP3 RHOG ERBB2 OR4D2 STAT6 OR4C3 AP2S1 TIA1 RGS17 KIF2A JAK2 HCAR1 OR51B2 RET OR1S1 WNT1 RGS4 CENPP LAMA2 MEMO1 FGFR1 TAB1 SRY PPP2R5B PSMD14 GLI1 OR2Y1 BDNF TIAM2 NCOA1 LPAR5 OR2L13 SPTBN2 ST3GAL4 IRAK4 LRP10 MOV10 HGFAC OPN4 DNM1 PRLH GMIP OR5K2 OR1E3 HNRNPF APLNR TFF1 SMAD5 PIK3CB PMEPA1 AMOTL2 C3 CSN2 FGD3 DUSP10 HSD17B6 COL4A5 FZD1 CBX6 SPRY1 HHIP OR2C1 ADAM12 RPS6KA1 ITGA2 USP8 MARK3 GATA3 SH2B1 OR1J1 ACTG1 RPS6KB2 DGKB APOE PARP1 NOXA1 TGFBR1 STUB1 HIST1H2BH RXRG ADORA1 KALRN DHRS4 GNA12 NOX3 CDC14A ARHGEF6 OR14L1P SH2D2A FGF22 OR12D3 CUL3 POLR2H WASF1 GPR45 ATP2A1 GTF2F2 OR4F15 STK3 LAMA4 CPT1A CYP26B1 NR5A2 ARHGAP10 GRP FRAT2 CHRM5 RGS18 PPP3CB RANGAP1 POLR2F GPR55 MT-RNR2 IL6R SMC1A CD80 TIAL1 GALR1 RASA4 JAG2 CSNK2A1 SKA2 LTB4R POLR2J RASGRP3 ZW10 GPR176 PIK3AP1 MAML1 OR13C5 GCG TSHB RAP1B ATP2A2 TAS2R20 GSK3A SEH1L KLK2 BCL2L11 EPAS1 CENPM CYP26C1 CCL1 SPTBN1 BUB1B HRH4 CRK TAS2R40 CARM1 RAG2 FAS CRH NTRK2 DIAPH3 DUSP1 ADCY10 E2F5 PRKCE OR1A1 RAC1 DISP2 MYLK OR52E5 ITGA2B GPR132 PARD6A OR10J5 GRK2 PDK3 OTULIN PIK3R1 PRKAG3 DNAJB1 GPR32 KRAS UTS2R FASLG OR2L5 GPR37L1 NEFL MAPK6 COL27A1 TCIRG1 PRKAA1 B4GALT1 CYP26A1 ADCY1 BCO2 DGKK ABL1 OR10A7 OR13C4 REEP1 COL5A3 F2 P2RY13 PSMA6 CDC37 OR5AC1 NMU CMA1 S1PR1 MAP2K1 USP9X ADAM17 OR5R1 POLR2L RASAL2 MYL12B ADORA2B LAMC1 SOX17 NUF2 TSC1 NRAS FPR3 CLTA NOTCH3 HTR1D ARAP1 MIB1 ITPR3 NOS3 RCOR1 BAX HIST2H3D OR56B4 DLL1 TAS2R39 HIF1A TMED5 ARHGAP4 GRIN2B OR10A2 OR7D2 MAPK14 DGKZ PSMD9 OR56A4 COL1A2 PCSK6 PPP1R12B AKR1C4 OR52B6 RFNG SKP1 RHOB SEC13 TACC3 ADH1C LEO1 ARHGAP33 COL6A2 RANBP9 SHC2 RARA RAD21 HCRTR2 OR10J4 NCAM1 LAMC2 HHAT TUBB4B ACTN2 IRS2 PSMD5 POU2F1 FGF23 TAS2R60 CDCA8 TNFRSF10B ATP6V1B1 RCVRN OR2W6P RAPGEF3 COL11A2 AWAT2 REEP6 P2RY1 LDLR OR4D1 ABI2 OR13H1 PDE6G PRMT1 OR2K2 CCR5 PHC1 SLC38A9 OR2B8P ESRP1 NELFB OR11H6 RAMP1 OR7G1 OR4A8 KANK1 OR9A1P GRIN2A NUP85 IL17RD HPN FGD1 BCL9 RNF31 POGLUT1 IL2RG CALM1 UCN3 DVL2 RHOU PAFAH1B1 GPSM1 CALCA OR56B1 GRM3 NRG4 COL4A2 PKN1 NUMB PTPN3 CENPN NMT1 H2AFX CCND3 OR6K3 FGF9 SPPL2A OR1D4 UBE2M DZIP1 ATP6V1A PPP1R14A FFAR3 GPR35 OR10X1 BMPR1B OR8D1 OR10V1 AGTR1 GUCA1C STAG1 RDH8 INSR RNF146 ARHGAP20 OR51E1 GOPC WIPF2 OR9A4 POLR2B MDM2 CXCR4 HDAC7 OR10J1 IGF1 NUDC RPS27A TUBA4B WWP2 CENPH NCOR2 XCL2 RASA3 TAS2R50 BCAR1 CHRM3 OR2T5 OR4F5 TLE3 RBP2 LGR6 P2RY4 CDC42EP3 RNF41 OR9Q2 RBX1 RHEB IL5 GUCA1A GAS8 OR52R1 OR10S1 RGR NCF2 USF2 MYC PSEN2 TAC1 SKIL CNKSR1 WNT10B OR2D2 OR1K1 ADCY2 METAP2 CSF2 OR51J1 THEM4 PDPK1 OR8U8 ARHGAP26 NLN MC5R SFN OR5I1 CCKBR ELMO1 MIS12 TAAR1 KDR FSHR AGRN OR1S2 SHB MAD2L1 HEY2 PLCB2 PSMA8 NRP2 GRM6 WNT7B PSME1 STRAP ATP6V1H CSF2RA NTF4 TP53 MECOM ATP6V0E1 PRKAA2 RPS6 NCBP2 IFT52 FGF20 OR10D3 PSMF1 RANBP2 OR1M1 ATP2A3 ABCA4 OR6C75 IL6 PPP1R1B TNS4 TERT OR52K1 HRH3 PPP2R5D CCL4L1 TAS2R19 RGS19 ANOS1 OR4F4 GPR4 LRIG1 OR6K2 WNT9B AKT3 NPY2R CD86 TSHR GRM7 CNR2 CNGA1 PTH2R OR10K2 RALBP1 FGF19 FGFBP2 IL33 CAMK2G WWOX MAPK1 MAPK4 NTSR2 TAAR3P ARPC5 ACVR2B PSMB4 OR5M10 CBX4 AGTR2 MYL6 SEL1L ARAP3 CLASP2 FGG PHB FYN OR6Q1 IER3 ALDH8A1 VPS26A PSMA3 TGIF1 RARB HCAR2 NOTUM OR2J1 WNT7A NR2E1 ESR1 THBS1 HIST1H2AC RDH5 NMS RGS16 OR2F1 PDGFA RASGRF2 PIK3CD PIK3R4 RDH11 RTKN TYK2 PSMB2 RHOT2 DAB2IP RIPK2 SMAD1 PRKACA GRM4 DERL2 SOCS6 RTP2 OR4C45 EDN1 FMNL2 CENPT OR10G4 ARHGEF35 PF4 SPTBN4 IFT88 CCR10 OR10H3 OPN3 SAG ALDH1A3 PDE1B MYH11 RAB4A NGFR ZNF217 DGKA PSMD3 TRIP10 PDE2A CALCR NMB NOTCH4 OR51G2 AP2A1 H3F3A FSTL1 TAS1R2 LAMA3 PRKAB1 OR13D1 PPP5C ARHGEF10 DKK2 KAT2B TUBA1B PSMA7 GRAP2 E2F1 PROK1 SHH RIT2 KLC1 DVL3 OR10G9 DEPDC7 RXFP4 GLI3 RCC2 ATP6V0D2 MKS1 KIF3A GPR17 OR6X1 KAT2A JUND OCRL RGS11 CHRM1 THBS4 MTMR4 ATP6V1G3 OPRM1 DUSP2 OR4K1 JUNB XCL1 PIK3CA VEGFB RALGDS IL6ST NRG2 KLC4 OR1F1 OR4C11 TAS2R46 GPHB5 CNTN1 POLR2E SH3GL3 POMC NRG1 DUSP3 PSMC4 IFT140 KEL TNRC6C OR5H6 RLN3 GNRH2 AKR1C1 OR2C3 GFAP DUSP16 PDHA2 OR2T6 APOC3 OR4A5 CCRL2 FZD4 RSPO4 OR2M3 BRAP OR52J3 TNKS HGF FGF6 CX3CR1 PIK3CG SSTR3 MMP3 RGS22 SOX2 OR4D10 OR2T1 DRD4 IGF2BP1 PPP1R12A LEP GRM1 OR10H4 PSMD11 MEN1 ARHGAP8 TAS1R1 LAMC3 ANGPT1 PTPN1 FCER2 ATP6V1E1 CHN2 OR1G1 OBSCN HNRNPA1 EFCAB7 NPSR1 PSMB10 GNA13 OR2T3 CBY1 LAMTOR4 LIMK1 OR4X1 PDHB TLE2 PEA15 OR4C6 ARHGAP30 APOA4 RGS9 FGF1 ATP6V0A4 EDNRA GPSM3 STAT5B DNER OR5G3 IL2 CDKN1A S100B DRD1 OR51L1 OR9I1 ARHGAP44 MDK MFNG PTPRO OR2L3 OR5H15 GNAT2 ARRB2 OR2A12 OXTR CBFB ATP6V1C2 TFDP1 OR2J2 CTSD RPGRIP1L AMHR2 NR3C1 CRABP2 OR2L8 RGS8 SPDL1 TAS2R41 OR4Q2 ACKR1 TAAR2 PMCH OR14A16 OR10AD1 OR3A4P DVL1 PSMD1 ETV4 FRS2 TLR9 SMAD2 AR FSTL3 HRAS HTR4 NCF4 H2BFS MEF2A SEPT7 CHRM4 RASA2 NTS EDN3 P2RY14 BMPR1A OR2T7 ABHD6 ITGB3BP ECE1 OR5T1 CHRDL1 OR2F2 RGS12 OR2L2 COL6A3 PPM1A HECW1 OR51M1 KSR2 ARHGEF5 ADH4 COL1A1 WDR83 IQGAP3 ARHGEF25 JAG1 OR4K15 ARHGAP18 GRK7 SH2B3 SPTB OR8D2 APOM RGS13 PSENEN ADCYAP1R1 ARHGAP29 CBL DACT1 OR5M1 OR2AG1 RAMP3 WNT16 OR8J1 S1PR4 USP7 SSTR4 BAG4 FLRT1 OR10A5 OR13C9 TNKS2 PNLIP GUCY2F MATK CNKSR2 KDM4B IRS1 CLPS ITCH GPR143 ARHGAP23 OR7G2 PENK SCT PTGIR PLEKHG2 OR13C8 WNT2B WIPF1 ARHGDIA OR4F17 LRAT MAPKAP1 ARF6 GNG4 AKT1 MCF2L OR52A1 PTEN OR52N5 ARHGAP12 PSMA5 OR2AP1 FNTB TUBAL3 NPB ADCY6 OR6N2 CDKN1B ADGRE1 ITGA3 ACTR2 GCGR ARHGEF16 FOXO3 VIPR1 YWHAQ CCR4 OR10R2 CCR6 OR56A1 APLN PSMC2 TAX1BP1 CDC20 OR4E1 THBS2 SFRP2 RBFOX2 FGF16 CDH1 WDR19 GPC1 PREX1 CCR2 GSK3B XK HCRT IQGAP2 ARHGEF2 STAP2 WIF1 DNAL4 OR10A6 OR10H5 LAMTOR2 TFF3 RTP5 GRIN2C ARPC1A CTNND1 GPR83 RHOA CALCB GRM2 SYDE2 GNG2 OPRK1 OR9G9 ACVR1B SOX6 FLNA MGLL OR1J2 CTNNA1 CDC25C SPTA1 DGKD RGS14 RAP1A TUBA4A OR6C3 OR11H4 TNFRSF10D FGFRL1 CXXC4 NR4A1 FOSB OR7D4 GRAP P2RY10 OR5AP2 OR10P1 PDGFRB CBX2 TUBB2B HTR1F TCF7L2 AES ABHD12 SH3GL2 TUBA1A ARHGEF37 GUCA1B LPAR3 TAAR8 OR2T2 OR1F2P DOCK7 APOA1 LRRK2 OR1B1 ADGRE3 PLCB4 RAMP2 BRK1 DLG4 SUCNR1 APC KLC2 OR5AL1 OR10A4 BCO1 TUBB8 CLTC RTN4R GPR183 KHDRBS3 TRIO BAD DRD3 NOG OR51F1 LAMB2 OXT NCF1 TAS2R3 NMUR1 VEGFC GAB1 KMT2D EIF4E OR6B3 OR2AT4 AGT PLXNB1 OR2T12 ECE2 OR2AK2 RAPGEF1 ATN1 ADAM10 OR52Z1 MAPK7 PIK3R6 OR2M2 ARHGEF33 MLN OR2H2 PEBP1 OR9A2 TRRAP DAAM1 SCAI PSMD7 ADRA1B HIST1H2BC DIAPH2 CDK5 CPT1B PRKCD SDR9C7 PXN TAS2R5 ATP6V0B CAMKMT CDC42EP5 BIRC3 DYNLL1 TUBA3E CLIP3 HTR2A HDAC8 NRP1 TULP3 OR5C1 RBP1 PRKCH S1PR5 PSMB11 FRAT1 ATP6AP1 SGO1 ASH2L HIST1H2AB CCNE1 DHRS3 IL2RB LRP6 SPC25 GPC4 PTCRA PSMB3 RARG CDC42EP2 COL5A1 OR4L1 RHOBTB2 SSTR5 PIK3R3 SDC1 LRP8 SMPD2 ADRA2C SEM1 OR4F6 PDE4D GLP1R OPN5 RGS5 HSPB1 GPR31 GHSR CD55 CDKN2B CXCL11 GTF2F1 PTAFR GPRC6A CXCL8 ZWINT ARHGEF11 ACKR4 OR2V2 OR8B4 APH1B CCL27 OR2T4 SOCS1 INPP5B ARHGAP17 UTS2B DYNC1I2 ERBB3 TBL1XR1 PLCG1 HSP90AB1 GFRA3 VRK3 OR8H3 AP2A2 DKK1 HEYL RLN2 OR4C46 CLIP1 CCL23 VAV3 BMP10 CSK CKAP5 MAP3K7 MAPRE1 PDE7B GREB1 OR11H2 NUP98 ADGRE5 OR52D1 OR11G2 RBBP5 LGR5 TAS2R31 GFRA4 CYLD STRADB QRFP GNG11 TAS2R43 SPTBN5 PRC1 MC1R PRKAG1 PELP1 OR5AK3P DGKH QRFPR OR1A2 RDH12 OR52A5 EREG COL9A3 TAS2R30 ARHGAP36 DDX5 FNTA POFUT1 LAMTOR1 STAT1 MKRN1 OR10H2 PPEF1 PHLPP2 GIP ABI1 PTGER4 USP21 PIK3C3 CYBA TAS2R8 YWHAB PTPRU PYGO2 SNAI1 OR13C2 NEDD4L ARHGEF15 GTF2A1 UBA52 DLC1 OR4X2 EGF AXIN1 CFTR OR8A1 TGFBR2 EGFR AURKB RDH13 ARHGEF38 EPS15L1 PTGFR HDAC10 KIDINS220 FSHB GPBAR1 OR2T11 ANXA1 HTR2C PTBP1 PLXND1 OR10G7 LRP2 OR6A2 CYSLTR1 OR5B12 GLI2 ARHGDIB OR5T3 GDNF PIK3R2 RHPN2 PGR H2AFV RXRB WNT3 ATP6V0D1 ARAP2 ARHGAP28 DYNLL2 ACTA2 ELMO2 ARHGAP11A OR4S2 TRADD GRK5 HIST1H3A OR6C74 ECT2 FRS3 PIP4K2B HGS OR5AN1 HIST1H2BD OR51B4 OR2I1P BCR OR4Q3 OPRL1 OR2B11 TACR2 EGR1 OR11H1 HTR5A CXCL3 TTR PYY PPARG RAB4B OR4C15 PKN3 TAS2R4 TAS1R3 ARHGAP24 OR51T1 RHOBTB1 NPBWR2 PSMB5 NDEL1 WNT2 NPBWR1 MRTFA OR13J1 WNT4 COL2A1 OR5L1 BUB1 ATP6V1B2 RBBP4 ACVR1C PBX1 MTA1 CDON VAV1 WWP1 OR10G2 INTU OR5P2 ADH1A PIP5K1A ERBB4 RING1 PREX2 ATF1 GPR18 XIAP LPAR2 FMNL1 SRC OR4C5 OR2J3 C5AR2 MAMLD1 CXCL5 ARHGAP35 CENPQ PTGDR2 EP300 GNAI1 TAS2R10 FLT3 OR10J6P ARHGAP1 XCR1 GRK6 GNAI2 CXCL10 RGS3 RXFP3 OR1L8 HIST1H2AJ BCL2 OR51D1 OR1E2 TAGAP SMAD3 PTH1R CREB1 KDM1A PDYN OS9 EDN2 NUP37 OR6M1 CXCR6 RGS9BP DKK4 DUSP9 WAS OR6C2 OR5A1 F2RL1 CDK9 FGF4 OR2V1 OR10W1 OR7C2 WNT5A FGF8 GNGT1 SH3GL1 OR2A42 OR5V1 GHRL SHC1 HDAC1 CCR8 MBD3 NF1 ZFYVE9 GLP2R AVP CXCL2 CHEK1 MAML3 ACTB IQGAP1 FZD3 OR1N1 DNM3 ADRB2 PPP2R1A DUSP4 ATP6V0A2 OR8U9 OR4D5 NTRK3 OR4B1 IAPP DOK1 OR9K2 ARHGEF39 CXCL16 KHDRBS1 ARHGAP32 OR5M8 PAK3 OR10D4P TUBB4A STAM2 OR52K2 OR2AJ1 OR8B12 WNT11 AKT2 NGF OR8B8 SMURF1 TNFRSF10A VCP LFNG NFKBIA PLK1 OR2AE1 GPC3 BEX3 OR51G1 OR51Q1 CAV1 CASP10 GATAD2B PPP1CC MAPK13 SPINT1 POLR2G RASGRP2 RASGRP4 PRKG2 SOST BTC REEP2 TUBA8 OR7G3 NOXO1 PDGFB WNT8B DRAP1 ERBIN FOS OR4A16 BMP2 ITPR1 KDM4C RNF2 SPHK1 PSMC1 P2RY11 PSMC6 REEP3 MAPK12 CXCR3 RICTOR CDC42 VCL OR51F2 NCOA3 GDF2 MAPK11 ARHGEF10L TAAR9 RHPN1 NMUR2 PPP2CA RHOF RHO VWF ELF3 UBC CXCL12 WNT3A RASA1 PTK2 COL4A4 BMI1 ARHGAP40 YBX1 GUCY2D HNRNPM SHC3 HCAR3 MYL9 GNGT2 FZD2 KNG1 PRLHR ITPR2 TNFSF10 OR5H2 TAS2R38 KPNA2 SPP1 PRICKLE1 GPR150 MTNR1A ZFYVE16 CRKL FOXA1 FGF10 WIPF3 PPP2CB ATP6V0A1 ACVRL1 S1PR3 PLPPR3 NPY1R HIST3H3 TRIM27 ROCK1 FAM13A SOS1 PTGDR TBP SAA1 POLR2K PDE7A GNAS SERPINE1 FGA PDHA1 RUNX3 KREMEN2 OR4K5 OR10G3 OR1P1 HIST1H2BA PPP1CA AXL ARAF VANGL2 AXIN2 WDR35 ADM OR52E8 OR6C65 CORT ARHGEF12 GRB7 PTPN2 WNT8A FGB TCF7L1 MAPKAPK3 MMP9 ZWILCH SALL4 MAG GNAI3 ALDH1A1 AGO4 PMF1 RTN4 NUP43 FABP5 TRAF1 CXXC5 IHH OR52N4 WWC1 OFD1 HTR7 OR5AK2 MEF2C RGS10 RPS6KA3 OR52L2P CNGB1 FGFBP1 AVPR2 SOX3 INS CD19 NPW MED1 OR13C3 STAT3 RPS6KB1 OR2B2 OR13G1 H2AFZ OR2W5 ARHGAP15 SDC3 RHOV OR2D3 NFKB1 MADD ATP6V1G1 VIPR2 OMG FGF7 P2RY12 HDAC9 OR5A2 SRGAP3 P4HB OR4N2 OR2G3 CTNNB1 ARRB1 PCSK5 SYNGAP1 OR6P1 RAPGEF4 PCP2 CYP4V2 IRS4 OR1L4 RBL1 CASP2 RNF111 EVL PYGO1 MAD1L1 NRIP1 FPR2 SPRY2 PDGFD DHH NPFFR1 CDK2 ARHGEF26 OR5M11 RXFP1 FZD9 CRABP1 EIF4EBP1 SOX9 CENPU TAB2 BAIAP2 SUFU GRK3 TNRC6A FURIN GNB3 TUBA1C SFPQ SMAD7 OR10AG1 OR1Q1 LATS2 TRAF2 MOB1A CSNK1E NCOA2 OR2H1 CDK1 SST OR3A2 CTBP2 FES GRIN1 OR2W1 REEP4 CAB39L AMH MLST8 GPR37 SMO GRIN2D OR5K3 TUBB6 GPNMB KIF7 ARHGAP25 DGKI ATP6V1E2 HTR1A DYNC2H1 AMOT OR10T2 ARHGEF18 PTK2B OR1L3 OR2W3 RASGRF1 MOB1B OR7C1 PSEN1 PTCH1 PRKG1 OR8G1 PRKCZ RXFP2 PTHLH APP RETSAT OR4S1 OPN1MW CENPS DHRS9 OR6B2 DYNC1LI2 ARHGAP5 OR14A2 ADCYAP1 ATP6V1G2 CXCR5 TGIF2 CCL5 CCL16 CHD8 HSPG2 RRAGB OR5T2 OR4N5 PPP3R1 PRKCA GPSM2 PTPRJ SPINT2 ZNRF3 PRKAB2 HIST1H2BO PPP2R1B ELK1 CMKLR1 DRD5 STK11 POLR2I EED ST3GAL6 OR1C1 OR52P1P SPOP CHUK HNRNPH1 GNRHR ROR2 OR10Q1 PPP2R5E OR5B3 PRKAR2A GPR25 MYH10 RGS6 PTGER2 COL6A1 GRM8 PDE3B NRG3 MAML2 RPS6KA2 GRPR FGD2 GNG8 OTUD3 FZD6 OR52H1 CDK8 TRPC3 PRKACG LCK IKBKB OR1L1 OR2A4 RELA KIF18A OR2A2 CHD4 AMER1 OR5H14 INSL3 GNAQ OR14C36 MAPKAPK2 PPP2R5A STARD8 OPRD1 GNB5 CCKAR OR52E1 DUSP6 ITSN1 GNAT3 NPFFR2 OR5AR1 OR4K3 PTPN11 ARHGAP27 SSTR2 GRB10 FGFR3 OR5D16 PKN2 GRK1 PAG1 OR6T1 ARHGEF40 EPN1 COL9A2 CCNC OR4D9 ADRA1A AP2M1 CCL28 OR4C12 RBP3 RUVBL1 SSTR1 ARHGAP42 HIST1H2AD ERCC6L HDAC5 GABBR1 OPHN1 OR10H1 RPE65 PTGER3 TGFA PSMD8 OR3A1 SMAD4 EZH2 PRKCI CREBBP TAS2R7 CCR9 CXCL13 OR1J4 DAGLA DGKG FLRT3 LAMTOR3 SPRED3 GRM5 ULK3 PSMD2 DUSP7 OR51I1 MKNK1 DTX2 JUN TRIB3 KISS1R CFL1 RIT1 ICOS GABBR2 PSMD12 AP2B1 COL6A5 SPTAN1 CCNT1 DGKE IL3RA RNF43 RDH10 ACKR3 GFRA2 PLAT FBXW7 PTPN18 MST1R PSMB8 VEGFD OR8D4 COL4A3 OR6C68 ARHGAP11B PLPPR2 LRP1 APH1A ACTR3 OR6F1 MET PGF OR51V1 OR1D5 P2RY6 PLPPR1 TUBB1 PSMD6 OR51A4 HIST2H2AC SPPL2B GNAL COL24A1 GIPR RRAGD GPR65 GNB1 OR4C16 PHC2 MTNR1B CUL1 OR6C76 DNM2 RPS27 OR5AS1 AMOTL1 PRKAR2B RHOJ RHOH ADCY9 WWTR1 ARHGEF9 C3AR1 DLL4 OR56A5 OR8U1 KIT CSNK2B OR4K2 METAP1 OR12D2 XPO1 MCHR1 KIF2C GNAZ OR10J3 BUB3 SYVN1 GTF2A2 DOCK1 TACR3 HBEGF LPL PAK2 OR8H1 TRH PSMB9 AGO3 LAT OR9G1 GNB4 THBS3 OR13F1 NEURL1B KTN1 TLE4 TLE1 CXCL9 TGFB1 CSNK2A2 NCOR1 SOX4 CHD1 COL11A1 NUP160 CTNNBIP1 SMC3 CCDC88C VIP GNB2 OR11L1 OR52A4P HDAC4 TLN1 OR2G2 S1PR2 KNTC1 PSMA2 OR52E4 ATP6V0E2 USP34 KIF5B RALB RIPK1 PDE6B FOXH1 LAMA1 OR1F12 BRS3 ADORA2A CALCRL MYO9B LEPR PSAP HDAC11 RXRA FZD8 ADRA2A PTPRA MAGED1 OR14J1 FZD10 YWHAH VPS29 CENPO FRK HIST1H2BL RDH16 CCR7 UCN CCL20 CGA FKBP4 OR7A2P FUZ ATP6V1F OR7A10 FFAR1 DAGLB PLG OR10K1 WNT6 EBAG9 TEK UBE2D3 PFN1 SMPD3 FGF18 DLK1 CILP OR4K17 HTR2B LAMTOR5 NCKAP1L REEP5 OR4C13 CENPC MYH9 OR5P3 OR2T8 CSF2RB HTR1E SCRIB DLAT FPR1 SMARCA4 TAAR5 LPAR4 RGS20 PPP1CB RASGEF1A OR5AU1 GPC5 GREM2 PTPN12 TCF7 CCL4 PTGER1 AATF RBCK1 LHCGR UTS2 HIST1H2BJ LYN CTTN LTB4R2 UCHL5 NET1 RAC2 TAS2R45 RAPGEF2 OR2T29 PSMD10 LPAR6 ADRA1D DGKQ LEF1 MTOR RGS21 STAM CASP8 TAS2R42 CENPK SH2B2 YWHAZ BDKRB1 ITGAV BAMBI HIST1H2BK PSMA4 OR2T27 STAT5A ALDH1A2 CER1 OR2M7 GDI1 RHOT1 RAG1 SDR16C5 BDKRB2 OR6N1 OR4K13 IL1RL1 PTPRK KLC3 SMAD9 MCF2 FLT4 GPR39 OR8G2P OR5M3 GRB2 TEC OR4D6 COL5A2 OR2T33 OR11A1 EVC WASL PRKAG2 TJP1 TIAM1 PIK3R5 RHOQ TNFRSF1A PROKR1 SP1 LIMK2 PRKAR1A F2RL3 RASGRP1 APOC2 OR5B2 WNT5B MUC20 OR52L1 REST NEDD8 TNFAIP3 PRDM4 MAP2K5 POLR2D GAST CSNK1A1 OR5M9 CENPA GNG12 IKBKG PSMA1 OR51B5 KHDRBS2 CYSLTR2 DEPDC1B OR5L2 IL2RA GALR3 ADCY4 KIF5A STK4 SPRED1 AGO1 CCK RHOC TAS2R16 OR9G4 ARHGDIG DYNC1H1 FADD STARD13 ARHGAP9 OR10C1 FKBP1A PDE1A LATS1 ITGB1 SLC24A1 OR8B3 ATP6V1C1 TAS2R13 FAM13B BRAF BMPR2 GPR20 RRAGA SPC24 KITLG EEF2K NTF3 MC2R OR7E24 RBBP7 PSMD4 ATP1B4 HIST2H2AA3 CNR1 VAV2 SMAD6 PRKACB CYFIP2 WASF2 FOXO1 SMURF2 ARHGEF7 APBB1IP SYK SAV1 ITGB3 OR6K6 OR4A47 CXCL6 C5 PHC3 ARHGAP22 OR4F21 HRH2 OR6V1 CCNK CCR3 OR52I2 IL1RAP GZMB DTX4 HEY1 ADCY3 DLD BTK KNL1 ATP6V0C RDH14 A2M PPARD KBTBD7 SCMH1 NFATC1 OR4A4P SRMS OR4N4 PSMB7 HIST1H2BM NLK CUL5 APOB
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Hierarchy Landscape

The following plot represents the hierarchical landscape of 'Signal Transduction'. The hierarchical tree allows to click on the pathways with children (black border) and continue the exploration. All nodes are colored by their source (click on the map for the legend) and cross-link to the original pathway page.

Sub-Pathways

About

ComPath is developed and maintained in an academic capacity by Daniel Domingo-Fernández and Charles Tapley Hoyt at the Fraunhofer SCAI Department of Bioinformatics. This web application relies on data loaded from KEGG, Reactome, and WikiPathways Restful APIs, as well as MSigDB. More information here.