Signal Transduction - Pathway Page
Name Signal Transduction
Resource Reactome
Genes CCR10 MAP2K2 GATAD2B FLT1 SMARCA4 BMP10 RBP1 TGFB1 SPINT1 ACTB ATP6V0A4 DKK2 RIT1 MTNR1A ATP2A3 PSMC4 OR7C2 ADRA2B YBX1 AURKB SEM1 PTPN6 PPP1R1B OPRL1 KIF14 OR2A4 IQCE COL6A5 PTGFR OR7E24 UBC OR2F2 OR2I1P TGFA PTPRA CXCR3 ARHGAP29 ACTR3 TUBA4B RAB6A ROR2 OR5T3 TUBB1 RHOB MKRN1 DUSP6 TNFRSF1A RCVRN ARHGAP44 OR9Q1 P2RY13 NPY2R PTH2R GAST F11R UBB CFLAR PSME2 LHCGR SEPT7 MST1R SLC38A9 RAMP2 CHRM3 LDLR OR52I2 CD80 NRG4 MDM2 SNAI2 FGA SPTA1 OR8H2 MLNR PSMD9 CXCL16 USP9X AXL AKAP13 NCOR2 CCNT2 GPR45 FFAR1 BDKRB2 SCUBE2 THBS1 RAC1 PPP1R12A OR6C1 SSTR2 GRM4 OR4P4 PLXNB1 GNRHR MATK VPS35 BIRC2 FZD5 GPR55 DEPDC7 DGKQ SAG SYK DKK4 RLN2 PIK3CB HDAC2 OR10H1 PRLHR OR10S1 HTR2A OR1F2P DHH FGF22 TBXA2R FOS CAMK2D GRM6 UCHL5 NCKAP1L H2AFZ PLCB3 OR52B6 TFDP1 KALRN CX3CR1 OR1D4 AVPR1B RAG1 GATA3 GNAI1 OR3A4P JAG2 ELMO2 TNS4 HHIP LIMK2 MLN CRHBP CENPF CHRM1 HDAC10 NOTCH1 GLP1R OR2V1 PRKAR2A BTRC AR CALCRL PTK6 GFRA2 LPL H2AFB1 WNT10A PPP1R15A OR5B2 OR7G2 GPSM2 ARHGAP8 GPR15 IKBKG RCC2 GFRA1 PRMT1 FGFR4 UCN3 GNA12 OR6N1 OR11A1 ACKR3 RXFP2 ITGB3 OR4F5 SAA1 CCNT1 PIK3R5 TCIRG1 OR6J1 USP13 CDK4 TAS2R38 DERL2 DRD2 CENPO POLR2J OR2L13 KIT PSPN BAX CHD4 GTF2A1 GGA3 GPIHBP1 CDC42EP5 EP300 KLC4 TAS1R3 MYH10 TAS1R1 RACGAP1 LGR6 RPS6KA1 SPC25 GMIP CAMK4 OR5B3 GNAL CGN PTPRO CYSLTR1 LRP2 ST3GAL3 HGS CRABP1 OPRK1 MAPK12 SPDL1 FMNL2 TAS2R1 OR2W5 HEY2 DUSP3 RPE65 RUVBL1 MYO9B NCF1 CDCA8 OR1E2 FFAR2 CDC42 COL6A6 LFNG CSNK2B CLTA NCOA1 GRK4 OR7D4 WNT9A RGS16 GATAD2A HIST2H2AC OR1G1 SHH MOV10 SMAD2 PDHX ROR1 TNRC6C DVL3 PTPRK SRY AGT ESR2 CENPP PLB1 GPR65 OR4C13 FNTB DYNC1I1 HTR2C CXCL11 OR1F12 HRAS GNG13 TRAF2 REEP5 GNG8 IL3RA GRK5 OR4M1 MKS1 OR4C46 TAGAP KSR1 IL1RL1 BMP2 CNR2 TRPC3 HNRNPF OR2C3 P2RY10 IFT172 PDGFRB PPP1R14A MYO7A WNT16 ABI1 DHRS3 PSMB8 PGR CCR3 ERBB4 AVPR2 GRIN1 LEPR KLHL12 CXCR5 RAB4B PIP4K2A QRFPR TRH REEP2 OR52N4 C5 IL6 NPHP4 OR5B21 PPARG OR8H1 OR8A1 NPS GCG JAG1 HECW1 OR6B2 UTS2B MAD2L1 SFRP2 OR51G1 ATP6V1E1 SGO2 CCL4 FLRT2 CDC42EP3 CBY1 OR52I1 FADD ERBB3 TAS2R30 PRKAG1 GPNMB PSMA8 DTX2 RTP1 DGKI OR4A8 GPC2 PTBP1 TIAM1 PSEN2 SH2B3 OR12D2 RRAGD NUP98 PEBP1 OR10D3 OR2T12 PTGER2 PEA15 ADRA2C PF4 RNF43 RPS6KA5 RARG APOC2 SDC3 HRH4 ADRA1A IQGAP1 OR10Q1 HSP90AB1 GRM7 PLCB1 STK4 FMNL3 KHDRBS2 DLK1 PARP1 E2F3 CYSLTR2 CASP8 ATP6AP1 SMAD7 CHD1 ERLEC1 CCL20 SKI KSR2 FZD2 OR51B5 IQGAP3 OR2T35 C3 OR2L2 TAS2R31 CMKLR1 HIST1H2BL STRA6 DGKH P2RY14 OR9Q2 LHB HSP90AA1 HTR4 RBFOX2 RFNG LAMC1 OR5G3 GSK3B OR10G2 OR1P1 SMO OR6M1 TRAF1 FZD7 OR6C68 SOCS1 OR56A5 DUSP8 REEP1 TNKS2 TAS2R7 OR2T33 COL4A1 GIPR IRS1 FZD9 TGIF2 SOX13 NAPEPLD SHC3 PDE4B OR52E2 OR1N2 TAS2R60 GPR20 DYNLL1 ADH1C FKBP4 YWHAE STUB1 CNTN1 CDK5 YY1 RHPN2 SMPD3 CTNNA1 OR10G6 PPP3CA SPOP OR4A5 RGS2 OR5H14 NUP133 CNKSR2 OCRL YWHAQ OR2J2 AGO3 GUCA1B STAT3 CTBP2 NRTN OR10Z1 CD19 AGTR2 GRPR OR5D13 USF2 CXXC4 BMPR1A PSMF1 OR1S2 PPP2R1B POLR2L OR8I2 PSMB7 OR2AJ1 DACT1 OR4Q2 LRP8 FURIN CYLD APP POLR2G WIPF2 PDE10A CYP26C1 PPBP MMP9 APOB ARHGEF11 OR5M9 COL4A5 COL9A3 PBX1 GAS8 GRK7 LRAT ARHGEF25 TMED5 PSMB11 KNG1 ITPR3 MTOR TAS2R46 CXCR4 OR2AE1 SAV1 CRKL OR52E4 ARAP1 OR8K5 LAMB3 MAP2K1 PLCB4 ARHGAP19 OR10W1 OR10H3 RTP3 S1PR3 TAS2R5 PMEPA1 OR10J3 CCNE1 OR4A47 PTGER4 ATP6V0E2 BAG4 PRC1 PDK3 LEO1 OR1L6 OR6P1 OR5D16 TRHR ITPR1 CAB39 SKIL IFT52 DOK1 TNFAIP3 PIK3R4 RTN4 CBX6 OPRM1 RAB4A EPAS1 AKR1B10 RGS1 PIK3R6 COL1A1 HTR1A JAK1 C5AR2 CSNK1A1 ST3GAL6 TGFBR2 NMS RAD21 DNAL4 PDK2 SOX6 TAS2R9 OR2H2 PROK1 RDH14 FER PPP1CA ATP2A2 PDE8B GHSR OR4K1 KBTBD7 OR5B17 OR6C4 OR2T11 TFF1 FOXO3 NMU GAL PSMB6 OR10A3 OR5L1 PLPPR5 TAAR8 CCL1 SCT FFAR3 SH2B2 CXXC5 PRKAA2 GRM2 OR4K2 MFNG OR14I1 PAK2 TAAR3P PSMD11 ATP6V0C CCL28 KLB FGFR1 PYGO1 MAMLD1 RARB IGF1 RALBP1 GREM2 FGF5 ATP6V1B1 PTPRU MTA2 OR5C1 MTNR1B GDF2 OR2T34 ARHGEF19 MTMR4 IL5 GNG11 PPP2R5E DGKA PPP1CC NPY1R FST CCND3 ATN1 AATF BDNF DEPDC1B RNF146 VPS29 LRP10 OR13C5 CENPU OR51E2 NCBP2 WWP2 ARHGAP9 ELF3 OR2B2 CDC14A CCL19 FABP5 FAM13A WWOX AKT2 RGS19 OR4C15 NOX3 NRAS RHOU SDR16C5 CTTN OR1B1 GAB1 OR8K1 OR2G2 ARHGAP10 KHDRBS3 AVPR1A TAS2R39 MKNK1 DOCK3 USP2 PLEKHG2 POLR2F KIF2A PTK2 BUB1 DUSP2 RXRB SNX3 CBX4 OR5M3 OR2T3 PIP5K1B FRS3 FRS2 REEP3 GRM1 RHOJ AP2A1 CCL27 KLC1 OR52J3 CXCR6 STAT5A RPTOR ATP6V0E1 BRK1 FRAT2 TNFRSF10B ADGRE3 POLR2A XCL1 OR10K1 GPHA2 SDR9C7 BRS3 OR4C3 OR5AP2 ARHGAP6 GRAP WNT11 KNL1 PDK4 OR13C8 OR8B3 CILP ATP2A1 OR5AC2 THBS4 PRKCD OR4Q3 IFT140 REST FFAR4 PDGFC NMBR OR1A2 COL1A2 WASF1 CENPA TEC EGR1 QRFP TLE1 STAT5B MTA1 MAML3 OXGR1 RPS6KB2 ARHGAP42 FPR1 OR2V2 RHOF CLPS CDK9 OR3A1 PORCN PDGFD FOXO1 PSMD13 SEL1L DRD3 SEC13 PPID BEX3 DHRS4 VAV2 OR1J4 PMF1 STK3 NMB RDH5 ARHGEF39 OR6K3 PTGER3 STAG1 GNA14 APBB1IP RBP2 GHRH RAC2 SOX3 VIPR2 GNAS RHPN1 TUBA1C OR10P1 NUF2 IL33 VANGL2 GPC5 PSMC5 RYK SH3GL1 CSNK2A1 PARD3 STAT6 SCRIB A2M NRIP1 SRMS KLK2 NLN NR5A2 GPHB5 RASAL2 HNRNPM MET PDHB PPP2CB IQGAP2 WNT4 FGFR3 OR51G2 PREX1 MC3R GPR18 SMAD6 HCAR1 TACR2 AMOTL1 ARHGEF3 RGSL1 CXCL8 GNAO1 FZD6 RBBP5 GRM8 OR2A42 PTH2 ARHGAP39 OR11H7 ZFYVE16 WNT7B OR14A2 DLL1 TYK2 RDH13 KEL OR10A7 MAPKAPK3 SMC1A HDAC8 PSMC3 WWTR1 CALCB CLTB KANK1 OR5H15 PRKAG3 P2RY2 OR2M4 OR2C1 CCL5 PPP2R5C PDE2A VEGFC NPB TRRAP LRP1 E2F5 OS9 PRKACA PDE4C PSEN1 NRG2 FGFRL1 ERCC6L PSMD1 PRKCG OR4D5 RPS6KA3 ALDH8A1 OR6B1 SUFU TFF3 OR1L3 STAM FLRT3 OR13C2 OR1E1 RANBP2 OR2AK2 IFT122 S1PR2 ADCY2 BCL2 OR5AU1 RHO POLR2D OR9G1 OR51H1 SPRED1 GSK3A NEURL1B OR56A4 FGF17 OR2G3 MAML2 ACVRL1 TAS2R8 OR10K2 CCL16 RET OR1I1 FKBP5 RXFP4 MEF2A PRLH CXCR1 APOA2 OR2T8 COL4A2 CYP26B1 RANBP9 TJP2 LPAR4 KLC2 GNB5 ARHGAP21 HES1 LAMTOR5 ARHGEF15 CXCL1 OR8B4 OR4E2 DHRS9 OR5K2 OR51A7 HDAC1 RBL1 ARHGAP40 OR5H1 STAM2 BTC PSMB1 GNG3 DUSP7 PTGER1 OR2L3 OR5A2 WASF3 IAPP POLR2H TULP3 SRC CPT1B APOC3 MYC PDE7A OR2M7 OR8B2 PTGDR PHLPP1 OR4S2 OR9A1P OR14A16 LGR4 GPC4 SKA1 TAAR5 OR2H1 USP8 IKBKB ARAP2 TAS2R20 MED1 OR10G7 MEN1 SPC24 HIST1H2AC TUBB2A ADRB3 RPS27 CCRL2 PRKAG2 ACVR1B RTP2 PDE6B OR5M8 PDE4D HCRTR2 TUBB4B PSMA6 ARHGEF5 FZD8 GTF2F2 WNT6 GRB7 ANGPT1 OR5M1 OR2W6P PRKAB2 DNM2 PTGES3 ABHD12 OR2A7 OR9K2 RTKN CALCR NR2E1 OR2B11 RASGRP4 OR52E1 SH2B1 CDKN1A SOST LIMK1 ZNF217 INPP5B OR1E3 MAPKAPK2 RAP1B OR4F15 SMPD2 SPRED2 GNAT2 MC2R OR2AP1 ARHGAP20 OR52H1 FGF16 ALDH1A3 OR51A2 AKAP9 CUL3 OR1K1 TNFSF10 PCSK6 CBL ADRA1B BCO1 HTR5A GHRL OR51I1 OR8J3 DVL2 VRK3 BIRC3 MAF1 OR14K1 PSMB2 LPAR6 ARHGEF26 OR4N4 CSK CCL21 OR7C1 LAMTOR1 PTPN11 PAK3 PDPK1 ARHGAP24 HRH3 OR5D18 GPR35 AHCYL1 COL9A2 OR7A17 PIK3R3 HES5 NSMAF LEP WNT10B LATS1 NOS3 LAMB2 OR8J2 LGR5 ARAP3 CLTC NPY4R GDI2 ROCK1 CAMKMT HTR6 ADRA2A MIS12 PRKG2 SRF HCRTR1 ARHGAP26 ARPC4 COL4A4 SYNGAP1 TBP CCL4L1 HRH1 IER3 ARHGAP33 SSTR5 GLP2R RAPGEF3 GPR4 TUBB3 TUBA4A TAS2R40 UTS2 THBS3 OR6C65 ARHGEF17 OR52E6 PDE3B PIK3C3 OTULIN CXCL6 CLIP3 OR5AN1 FGD3 PENK YES1 HIST1H2AD EDN1 NCKAP1 NCKIPSD WNT7A PRKCA MYL9 OR6V1 FABP7 NPSR1 GZMB ATF2 CXCL5 PSENEN GPR132 WDR83 OPN5 SH3KBP1 POLR2B FOSB MAPK13 IL1RAP CYP4V2 ERBIN PHB NPW PSMB5 EPS15 KREMEN2 VAV1 AXIN2 PLPPR2 OR4N2 OR4D10 IL2RB OR10AG1 NLK CRK TRIB3 IFT88 BMPR2 AMOT PRICKLE1 ARHGEF40 CCR2 RHOBTB1 XPO1 BDKRB1 GRP RDH10 CDK1 RHOV OR2A12 PIP5K1C RASA2 OTUD7B ARHGAP32 CYFIP2 FGF20 SPTBN2 DIAPH3 PPM1A OR4F16 FLT3LG GNG10 LAMA5 HDAC6 OR8G1 GRAP2 F2R PDYN WWP1 RGS4 NTRK1 HEY1 RHOC MT-RNR2 ARHGAP31 PRKAR2B ARHGEF38 DRD5 TUBB4A NOXA1 OR1Q1 NCK1 NET1 CASR PTEN P4HB SFRP1 ACVR2B HCAR2 GPR39 PPARD SEH1L SSTR4 LRP6 TERT SYDE1 OR4F17 HSD17B6 TRPC7 IKZF1 TAOK1 OR2J3 GALR1 ACTR2 WNT8A TGIF1 ARHGEF1 CCND1 ADH4 MCHR2 ABL1 PSMD2 LAMTOR3 OR5F1 NF1 YWHAG OR6C3 CTSD NOXO1 CGA OR52N1 TNRC6A PLPPR3 USP15 DOCK1 ZWINT PTPN1 AMER1 DAAM1 SRGAP1 PLCG1 PPP5C PSMA2 NEFL RAG2 OFD1 ARHGAP22 ATP6V0A2 OR6X1 SOCS6 OR9G4 PDE4A GNA13 OR2T5 MUC20 ADCY4 PNOC SFPQ HIST3H2BB SDC4 DLD RALB PPY OR14C36 PAFAH1B1 FES ARHGEF10 HTR7 OR9G9 MIB1 PCSK5 PTCH2 GNGT1 PROK2 NPY5R PRKAB1 OR52A5 AGRN CXCL9 OR10H5 WAS VPS26A DGKG DYNC1LI1 PAK1 DYNC1I2 LPAR1 CSF2RA RHOBTB2 ADORA3 PTPN3 RGS17 GALNT3 DYNC1H1 CASP9 OR2K2 PDGFRA PSMA7 PSMC6 SUCNR1 OR7A10 OR5T2 CENPT TTR EPS15L1 CCNC PDE11A SDC1 BCL9L EZH2 RPS6 RGS18 CTNNB1 MYH11 PSMD10 GDI1 SPTAN1 PRKCZ COL5A3 OPN1MW RLBP1 WNT8B ARHGAP11B AXIN1 STRAP OR6C75 ARHGDIB KDM1A OR1L4 GPAM HIST2H4A DNM3 PROKR1 S1PR5 OR52R1 HDAC4 ESR1 CTNND1 ARHGAP5 SOX4 OMG SNAI1 S1PR1 CAV1 NTS RUNX1 OR4D9 OR4K14 OR4C11 OR2B3 DISP2 IL6ST ACTN2 CNGA1 TBL1XR1 AMH TNFRSF10D PSMD5 CHN1 ABCA4 SQSTM1 CDH1 FGF6 CYP26A1 EVC2 FLRT1 CKAP5 APLNR HDAC3 HIST1H2BM OR52A4P NDC80 APC STARD8 NUP85 NRP1 ITGB3BP ADH1A DRD1 OR51F1 CDK5R1 TAAR1 IL3 CDK2 LAMC3 CASP10 H2AFJ RASA4 ARHGAP27 RBX1 RHOT1 OR8D2 RXFP3 RING1 TLE4 GAB2 FOXA1 COL6A2 PROKR2 PSMD7 OR4C6 RELA PTPRJ MAPK8 STAG2 PRKCI CMA1 CENPI OR1J2 TUBAL3 TAC3 PSMD3 OR52M1 DUSP1 OR6C70 OR2AG1 OXER1 AGO4 STARD13 ARHGEF33 ARHGEF16 OR2M2 ITGA2B OR13C9 AKR1C4 ELMO1 CENPE ABR CD28 TCF7L1 OR6Y1 RHOQ NUMB GAS1 UTS2R OR2A5 SOX2 OR5AK2 AVP HDAC11 PELP1 OR4F21 KAT2B TIA1 SMAD3 PTH MYH14 CREB1 LRRK2 IRS4 IL17RD KIF5A NCOA3 OR13J1 COL2A1 MYLK IHH NEDD4 SMAD1 PDK1 HTR2B RAMP3 ARHGEF18 CHRM4 NEDD4L ARF6 OR2L5 RGS8 ALDH1A2 OR5M10 TP53 CSF2RB SPTB GPR37L1 KIF2C HIST1H2BA KMT2D BMI1 USF1 BAIAP2 TRPC6 OR10T2 OR4K15 EVC GRIN2D WASL ARHGAP15 BIRC5 OR4S1 OR4M2 FASLG NUP160 MYL6 OR2Z1 HIST1H2AJ P2RY11 SHB HIST1H2BK TRIM27 MAML1 ECE1 OR4F4 RPGRIP1L MIB2 TAS1R2 RALGDS OR1L8 TRIM33 OR6C2 THBS2 SALL4 SPTBN5 PRDM4 PSMD4 OR52Z1 SPRY1 OR2AT4 SMC3 BTK RAMP1 E2F4 RSPO2 CALM1 SHARPIN ELK1 MYL12B PDE1A PSMC1 ITGA3 CTBP1 XCL2 NUP37 OR2W1 NOTUM POLR2C TAS2R45 OR11H4 ADRB2 POMC LAMC2 BCO2 FGF7 CSF2 OR10A2 FYN LAMA4 ARHGAP36 RCOR1 GPR176 STRADA ADRA1D POLR2E ARPC1A CSNK1G2 ADAM12 RGS7 VAV3 GABBR1 OR6F1 GPR27 TAAR6 BCAR1 ARHGEF2 CARM1 RGS9BP TNRC6B PTCH1 KISS1R YAP1 ARHGEF35 COL4A3 PML OR3A3 OR1N1 PXN DOCK7 WIPF1 GLI1 ARAF MAPK3 FNTA PTH1R AMHR2 OR10C1 SPP1 RGS12 TAS2R42 MAPK7 CAMK2B DAGLB OR13D1 SIRT6 KITLG NFKB1 RTP5 FGF2 NCSTN GLI3 OR6K6 CENPL PRKAA1 FUZ CHUK OR52A1 OR5I1 AWAT2 OR5K3 PFN1 OR5V1 OR10AD1 TRIP10 WLS SKP1 DNAJB1 FAS COL11A1 OR1A1 GRIN2C ACVR2A CHEK1 RGS13 OR4A16 UBA52 RHOH CCDC88C OR4C16 RASGRP1 ADORA2A SCAI ROPN1 B4GALT1 OR56B2P SOCS3 E2F1 MMP3 GPR25 ALDH1A1 GUCY2F PTPRS NMUR1 CYBB FSTL3 OR8B12 LATS2 CSNK1E ARHGEF37 HGF MAPK4 RXRA P2RY4 CENPS FAM13B PTPN18 EGF HDAC9 KIF18A CDC37 OR10A5 MAPKAP1 RNF41 RANBP10 WIPF3 ARPC5 SYVN1 HIST1H2AB GPER1 IRS2 GTF2F1 ADCY1 P2RY12 MRTFA PSMB10 OR4B1 MAPRE1 CENPH OPN1SW DGKE RDH12 WNT5B DUSP16 CDC25C GPC1 TLE3 FSHB SOS1 CER1 NPBWR2 KDR SH2D2A TAB3 AP2B1 AGTR1 ADCY6 ADCYAP1R1 PLXND1 RTP4 CXCL10 CHRM2 KIF5B HIST2H2AA3 KPNA2 SMURF2 MAG EDNRB KRAS OR4D11 TSC2 OR4K5 GTF2A2 DGKD ITSN1 GNB1 ADCY7 APH1A EED CASP3 GNRH1 NRG3 OBSCN JUND LIN7B PDE8A GNB3 CBX2 RGS11 TCF7 ATP6V1E2 TAB1 SPPL2A OR13H1 GNA11 ATP6V1B2 TMED2 TJP1 ADORA2B CXCL12 CDK8 KCTD6 ATP6V1A NDE1 MYD88 OR13A1 GPR37 AKR1C3 OR2J1 USP34 SCMH1 ABHD6 PTHLH BUB1B EEF2K OR8D4 PTPN2 OR14L1P LCK OR52N5 DSN1 RXRG FGF3 OR52D1 TAS2R41 DUSP10 MEMO1 BUB3 SRGAP2 CDH5 COL5A2 ECE2 RSPO4 OR13C4 GFAP TAS2R14 PTGDR2 ADCY5 POGLUT1 PRKCQ OR56B4 OR2L8 PLA2G4A SYDE2 RASA1 OR2T29 OR14J1 SOX9 H2BFS OR52P1P METAP1 ARHGAP30 PPP2R5A RBBP4 OR8G5 OR1L1 WNT2B PPP2R1A ARHGAP28 OR5AK3P OR10R2 PIK3CA OR4K17 DAB2IP LAMA3 OR52L2P PTCRA PLEKHG5 PPP3CC ULK3 GABBR2 CHRDL1 RIPK1 GUCA1C CCL23 LEF1 FBXW7 CBX8 KNTC1 MC4R OR2AG2 ARHGAP4 OR7A5 SDC2 CNKSR1 PLPPR1 TLR9 PIK3R2 OR10J4 LAMTOR4 NPFF NTF4 SPTBN1 NRP2 SMAD9 NCOR1 ITCH RHOD PDE3A KREMEN1 OR4D1 MGLL GUCA1A FGB CBFB NPFFR2 LAMA2 HIST1H3A GRK6 HRH2 OR10G4 SHC1 PRKCH SMURF1 PSMA3 KIDINS220 LTB4R2 OR8J1 PKN3 KTN1 OR10A6 B9D2 ANOS1 OR52K2 COL27A1 BAD ANXA1 INCENP PTPN12 TAS2R50 OR2B8P OR52L1 F2RL1 STK11 RGS22 OR11G2 OR4F6 PRKAR1A IL5RA RDH11 RAP1A ARHGAP18 RASGRP2 OR56A3 NR3C1 TNS3 PIP4K2B UBE2D1 OR4K3 TNFRSF10A DYNC1LI2 MOB1A GNG4 DIAPH1 TAS2R19 PRKACG CCK OR3A2 TRAT1 F2RL3 RGS5 LAMA1 CRABP2 PLPPR4 MYO9A OR51B2 TAX1BP1 ATF1 ST3GAL4 SFN OR10H2 CAB39L OR5B12 OR8U9 INSL3 COL24A1 MARK3 PAQR3 ARHGEF7 ZW10 OR2A14 OR4L1 NRG1 TAS2R10 OR9A2 HGFAC RHOT2 OR51E1 ARHGAP23 RAF1 ADGRE5 GPR17 OR2Y1 RSPO1 ETV4 THEM4 PDE1C ARTN ARHGDIG CCR6 SNW1 PIK3R1 PDE7B UBE2D3 TAS2R3 OR10J1 PSME1 PHC3 PDGFA KISS1 FRAT1 CXCL3 HTR1D CUL1 RGS14 LRP5 ADCYAP1 NR4A1 GRK3 NCK2 WASF2 NCOA2 GPSM1 TRAF6 FSTL1 ARHGDIA CLASP2 GRM5 OR5P3 OR56B1 FGG OR5AL1 FOXO4 RHOA ABI2 FGFBP2 RRAGB PGF RPS6KA2 RIPK2 CCL13 FGFBP3 ACVR1C PRKACB TAS2R16 OR2W3 CENPQ ADAM17 BRAP HBEGF FSHR BAMBI PSMA5 ITGA2 PTAFR OR2T7 ATP6V1F OR51Q1 DUSP5 RASGRF2 OR7A2P ATP6V0D1 RRAGC EIF4B FGFR2 SP1 PSMD12 GNG12 FRK SH3GL3 RICTOR RASGRF1 LAMTOR2 SERPINE1 ROCK2 ATP6V1G2 TUBA1A CREBBP MC5R H3F3A TAAR9 APLN CLASP1 TIAL1 PDE6A OR51V1 OR51F2 PPP1R12B RPS6KB1 FGF8 PSMB4 MOB1B DLC1 MAPK11 CCR1 FGF4 OR2S2 PPP3CB CASP2 POLR2I GPC3 ACKR1 DTX4 GNAT3 WWC1 PIK3AP1 RARA ADCY10 RHEB GUCY2D NUP107 OR51B4 MECOM DRAP1 ATP6V1G3 ARRB1 INHBB HTR1E DIAPH2 P2RY1 PPP2CA OR6B3 JUP RANGAP1 FCER2 GPR31 SHC2 CAMK2G EPN1 ZNRF3 NCF2 PSMA4 ACKR4 CCKAR GLI2 IL2RA IL2 OPN4 KAT2A SSTR1 APOA1 OR56A1 EGFR YWHAB VEGFA VCP COL3A1 CALCA MAD1L1 OR5H6 SPOPL CLIP1 RSPO3 EDN2 ATP6V1D HEBP1 MYB CDC73 NDEL1 RHOG GPR68 OR11L1 METAP2 CXCR2 RAPGEF1 FLNA OR5AS1 RAPGEF4 CENPM PDHA2 KLK3 HIST2H2BE RGS9 COL6A3 KDM4C NTF3 CNR1 WNT5A DYNC2H1 BCR VEGFB JAK3 PHC2 SPRY2 MADD OTUD3 TUBB2B NELFB C5AR1 SPTBN4 NTRK2 CIT IGF2 FOXH1 LYN TAX1BP3 CPT1A NMT2 IRAK1 OR2T2 NSL1 ATP6V1C1 DNM1 EVL CCR4 SLC24A1 PKN2 TLE2 DLGAP5 MBD3 ARHGAP35 NTSR2 NCF4 COL11A2 OR5D14 HIF1A OR12D3 IGF1R ARHGAP11A STRADB NTSR1 XIAP EBAG9 PPP3R1 ADORA1 OR5P2 OR2T27 PYGO2 RRAGA FGF1 TAS2R4 LPAR3 OPRD1 OR11H1 FPR3 XCR1 TAS2R13 APH1B MCF2 DLG4 GDNF OR6C76 GNRH2 WNT3A TNF PIP5K1A TSHB TCF7L2 ATP1B4 DTX1 HIST1H2BH GNAT1 OR8U8 TFDP2 OR2D3 SST PRKG1 OR5W2 IL6R PIK3CD GRB10 HNRNPA1 REEP6 OR5R1 NPFFR1 NGEF OR52E8 GPBAR1 SPPL2B GALR3 AKT1 EFCAB7 NOX1 OR51S1 OR51B6 NGF UBE2M VIPR1 PTK2B INSR RGR GNB2 CORT PARD6A OR51A4 SSTR3 P2RY6 ATP6V1C2 WNT9B NUDC PDE6G CHD8 VWF PYY FPR2 POLR2K ARHGAP25 NOTCH4 SPRED3 CDKN1B TAAR2 PLG DGKK ARHGAP12 HSPB1 HIST1H2BN MCF2L PCP2 COL6A1 OR4C5 DLL4 LPAR5 OR52E5 BMPR1B OR5AC1 CENPK EREG CD55 OR9A4 PKN1 NMUR2 TUBA8 OR2F1 OR4K13 ARHGEF9 HEYL JUNB OR4X1 BOC KHDRBS1 GPR32 CCR9 GNAZ CFTR ARHGEF6 OR2M5 OR9I1 OR2A25 RBPJ PRKAR1B PIP4K2C NF2 RNF2 ADM ITGB1 MLST8 NEURL1 CCR7 OR6C6 NPY CDKN2B PSMB9 TIAM2 DVL1 COL5A1 WDR19 ADCY9 OR51L1 NCAM1 MAPK6 GRB2 OR8S1 OR7G1 AKR1C1 RTN4R FZD4 HIST1H2BD OR2B6 ADM2 CCKBR TACR1 TACC3 AP2A2 IRAK4 OPN1LW STAP2 PSMD6 CCL25 GNG5 FGD2 PAG1 S1PR4 CYBA CSN2 TSHR FZD1 SOS2 TACR3 FZD10 OR2T6 RPS27A ARHGEF4 INSL5 POFUT1 NMT1 SMAD4 IL2RG SPINT2 AKT1S1 OR13C3 ARHGAP1 DKK1 FLT3 CRHR2 OR5L2 OR1D2 USP4 S100B PSMD8 GNAI3 AP2M1 MCHR1 FN1 CTNNBIP1 LPAR2 RNF111 H2AFV USP21 ARHGEF12 OR10AC1 AP2S1 OR1D5 OR6S1 GPR143 APOE GNA15 CHN2 CD86 OR4E1 CCNK GFRA4 TEK PTGIR ATP6V0B ARPC1B CDC42EP2 FGD1 OR2T1 DNER GRM3 CDC14B ITPR2 TUBB8 LAMB1 HSPG2 YWHAH AGO1 HPN FGF18 GCGR SOX17 APOA4 EIF4EBP1 SOX7 SH3GL2 FKBP1A HDAC7 CYFIP1 COL9A1 ADCY8 FZD3 CUL5 ARRB2 CDON MAPK14 CENPN REEP4 CAMK2A VCL VIP GRK2 STAT1 CXCL13 ACTG1 FGF9 TAS2R43 RGS21 OR10H4 OR13G1 EDN3 ADGRE1 NPBWR1 LINGO1 JAK2 OR5T1 OR10J6P JUN OR5K1 KAT5 DYNLL2 OR2G6 OR51J1 DGKZ PSMB3 OR4C45 OR52K1 LTB4R TUBA1B GFRA3 ATP6V0D2 PLAT PDGFB OR10G9 MAP2K5 PREX2 TLN1 OR10G3 DRD4 TUBA3E CRH RLN3 PIK3CG OR2T10 LAT OR8K3 EIF4G1 OR4C12 GRK1 OPHN1 MEF2C GNB4 HNRNPH1 TUBB6 PPP2R5D RDH16 PFN2 SGO1 OR10V1 BCL2L11 OR52W1 CHRM5 USP7 WDR35 OR2D2 ATP6V0A1 AKT3 FLT4 DZIP1 ZWILCH ECT2 OR5H2 OR8D1 OR4A4P RAPGEF2 OR51M1 WNT1 RGS6 NUP43 TRIO CITED1 NGFR GPSM3 CDC20 CENPC GRIN2A DGKB OR4D2 CCR5 GOPC CFL1 PHC1 CCR8 OR8H3 ADCY3 RAC3 SUZ12 TGFBR1 PSME4 PLCB2 PPP2R5B KIF2B AGO2 NCBP1 KIF3A NTRK3 RIT2 OR6A2 SKA2 NEDD8 GREB1 DUSP9 ARPC3 OR10X1 HCAR3 GPR161 KLC3 PRKCE ERBB2 HIST1H2BC DAGLA HHAT UCN INHBA F2 BCL9 RACK1 ARHGAP45 GALR2 IGF2BP1 OR5A1 FMNL1 EDNRA RGS3 OR4X2 SMAD5 TBL1X INTU ESRP2 H2AFX RASA3 OXTR OR5AR1 MAGED1 WNT3 OR7G3 KL ICOS RBP3 OR1J1 TNKS FGF19 CNGB1 RASGRP3 OR6K2 HIST1H2BO HTR1F AMOTL2 OR10G8 LRP12 RGS10 AES HIST1H2BJ ZFYVE9 RXFP1 GPR150 HCRT POU2F1 MAPKAPK5 HIST1H2BB OR10A4 GHRHR FGF10 DUSP4 OR10J5 RGS20 RALA TSC1 HDAC5 OR6C74 OR4D6 XK OPN3 NOTCH3 GNAQ CSNK2A2 PHLPP2 FGD4 MAP3K11 TTC21B KIF7 HIST2H3D WNT2 LRIG1 TRADD OR1F1 INS UCN2 OR6T1 GNG7 GPR183 HTR1B RBP4 MC1R WIF1 OR1C1 EIF4E PDHA1 MST1 OR52N2 PSMD14 OR4N5 ARHGAP17 HIST3H3 ARPC2 ACTA2 ITGAV MYH9 RUNX3 ADRB1 OR52B2 ATP6V1H OR51T1 GPRC6A PLK1 CRHR1 DLAT RASAL3 APOM TAB2 BRAF RNF31 GPR83 NFKBIA GNRHR2 OR5J2 PSAP GNGT2 RBBP7 PMCH OR8B8 OR2T4 ADAM10 OR1S1 GRIN2B OR1M1 NOTCH2 OR6Q1 PRR5 OXT YWHAZ ASH2L OR8U1 RDH8 OR5M11 CHD3 RASAL1 SCTR NFATC1 C3AR1 ATP6V1G1 RRH SPHK1 GNAI2 SRGAP3 GIP GNG2 PSMA1 OR2A2 RBCK1 VEGFD MAP3K7 OR13F1 OR2M3 OR51D1 PSME3 CXCL2 PDE1B FGF23 RETSAT PPEF1 DDX5 OR8G2P OR11H6 F2RL2 RASGEF1A OR51I2 OR6N2 OR4A15 KDM4B OR10D4P NOG ESRP1 ARHGEF10L ADGRE2 MTA3 OR7D2 CX3CL1 PSMC2 FGFBP1 OR11H2 PNLIP HSD17B1 MDK GPC6 MAPK1 GPR84 IFT57 AHCTF1 PRKCB PPP1CB OR5K4 TAC1
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Hierarchy Landscape

The following plot represents the hierarchical landscape of 'Signal Transduction'. The hierarchical tree allows to click on the pathways with children (black border) and continue the exploration. All nodes are colored by their source (click on the map for the legend) and cross-link to the original pathway page.

Sub-Pathways

About

ComPath is developed and maintained in an academic capacity by Daniel Domingo-Fernández and Charles Tapley Hoyt at the Fraunhofer SCAI Department of Bioinformatics. This web application relies on data loaded from KEGG, Reactome, and WikiPathways Restful APIs, as well as MSigDB. More information here.