Signal Transduction - Pathway Page
Name Signal Transduction
Resource Reactome
Genes HCRTR2 JUN HPN OR8D4 TRPC7 GOPC ERBIN DDX5 P4HB C5AR1 CHRM1 OR6S1 SMPD2 HIST1H2AJ CALCRL CDC25C STAP2 FGFR2 OR2A2 SIRT6 CCL13 TSC2 CFTR NCOA3 NPY4R AKT1 WNT8A BMPR1B CTBP1 OR1S2 VPS29 FFAR3 BOC UBE2D1 TMED5 GNRHR2 MLNR IL2 LTB4R PSMD1 MAP2K2 ROCK1 RASGRP3 OR10C1 OR1D4 PTPN3 H2AFX PAK1 NPBWR2 SRMS EIF4E OR6C74 OR4F5 OR2AP1 EDNRA CXXC4 OR2AE1 ADH1C CYP26C1 OR4C45 OR5F1 PDGFC TNS3 PPP3CA RPS27A OR6A2 ARHGAP31 OR56B2P REEP6 PFN2 GRAP2 HES1 GNAI1 CYLD OXER1 GPAM EED PDE3B IAPP OR5AK2 PPP2R5E USP8 SFPQ HEY2 GRM5 SHC2 OR13C8 TIAL1 TULP3 OR51F2 P2RY6 PIK3R2 ADM UTS2B TUBAL3 DVL3 MLST8 PRKAB2 FER DRD2 OR5P3 OR1F2P ARHGAP39 OR1J4 E2F3 KDM4B ADCY10 NCOA2 CHRM3 KCTD6 MYL9 OR52J3 TRRAP RET P2RY13 OR5M1 PSMD5 CENPL HHAT HIST1H2BJ RAMP1 POLR2E MYC ST3GAL4 BRS3 DOCK3 KLC1 OR11H6 OR52L2P CCL16 OR5AC1 GPRC6A CHN1 WLS SEM1 CTNNA1 BCR OPRL1 APOE TGIF1 EP300 OR13J1 CKAP5 OR8B3 GRIN2C SOCS6 ARHGAP17 CYP26A1 ARHGAP33 TUBA1B HTR7 GNAI2 OR52P1P NGFR ADH4 AGO1 GREB1 RIT2 CBFB KLC2 RAMP2 OPN1SW COL27A1 CLTB OR9Q2 FZD8 USP2 MAMLD1 DUSP8 OR13C5 CREB1 ATP6V1B2 HSD17B1 WNT3A GPR15 ZFYVE16 PEBP1 FFAR2 SMC3 TRIO HIF1A NPSR1 LTB4R2 CALM1 CCL20 TACR2 OR2C1 GPBAR1 ERCC6L NPBWR1 RXFP2 ADCY1 RUNX1 OR6F1 UCN3 OR5M3 TERT OR5D14 AES SNAI2 SMAD6 ARHGAP10 ABHD12 SEH1L LRP5 PDGFB ARHGEF12 H3F3A OR2J1 PSEN1 ARAF NCSTN TIAM1 PSMC3 ITCH TRHR PPP1CB GFAP GNAT2 SH3GL1 HEY1 FLRT2 SPPL2A GPR32 SRGAP1 KHDRBS2 PPARG SPTBN1 MYL6 GPNMB OR13C3 GPR143 REEP4 RHOF PSMC5 KISS1 BCL9 GPR176 IL2RG GPR25 RTP2 PSMD14 GIPR COL4A5 TAS2R43 GNA12 OR1B1 OR14A16 KLK3 OR5D16 OR9G9 OR10A5 STAT5B CENPC CGA NTS PENK SHB SMO OR5B17 IFT172 FSTL1 ARHGAP21 CFLAR OR56A5 HIST2H3D PRKAR2A APOM POLR2K TAB2 OR1G1 RHO FGFR3 KLK2 HTR5A RSPO3 SOX9 IFT52 ARPC1A SOX2 CNGB1 FADD COL4A4 ZWILCH DTX1 BMI1 WNT10B SPTA1 FRAT2 PSMC1 UCHL5 OTULIN OR8A1 PRKG1 OFD1 GDI2 PDE4D KPNA2 PSME1 PDHA2 AKR1C1 TLE4 IRAK4 SMAD2 WNT2 POGLUT1 OR52E2 HDAC1 TAS2R45 CASP9 ARHGEF7 OR56B1 UTS2R OR5B21 OR10G2 WNT3 HEBP1 FGF1 CSNK1E ARHGEF1 CUL3 NCOA1 DIAPH3 AP2A2 FGD1 SMAD9 OR4S2 PIK3R4 OR4C12 ACTR2 FGFR1 FZD3 TLE2 OR5K4 TIAM2 ADORA2B OR4N5 FRS2 OR7A17 APH1B SOX17 ALDH1A3 IRS2 ARHGAP27 OR12D3 RALGDS FAM13B RIPK2 ITGA2B OR10G8 ARTN KISS1R OR52R1 F2R HCRT TCF7L1 PPP1R12A KREMEN2 TAX1BP3 PSMC2 ADRA1A MTA3 PPP1CC PSME3 OR10G9 PARD3 NEURL1 P2RY2 KIT DNAJB1 SFRP1 OR8J3 LPAR4 RDH11 OR10J5 TAS1R3 CSNK2A2 OR9I1 SPRY2 HECW1 OR10A6 AKT1S1 ESR2 ROR1 MYH14 CCL27 OR7G3 AP2A1 GPC5 ARHGAP11A CENPP TRPC3 GTF2A2 RUNX3 RASAL2 LAMA2 PSEN2 HIST1H2BK CENPS WNT10A CYSLTR2 APBB1IP PTGFR OPN5 CCR7 HHIP DUSP5 OR8B2 PRKCD OR4D5 SH2B2 CENPH CXCL16 FGF4 PRC1 SPHK1 KMT2D PIK3C3 PDE8B DVL1 SOX3 RNF111 RHOBTB1 GNG13 ARHGAP29 CAB39 VCP EDNRB YWHAH OR4F21 SPDL1 QRFPR CSF2 HDAC2 NUP133 NGEF PIP4K2B OR2A14 OR2T7 APOC3 OR1L1 JUNB CENPK KIF2C OR2V1 WNT6 TRIM33 AGO2 POLR2I OCRL ARHGEF11 PRKAB1 FOXO3 OR52E1 PSME4 OR10V1 RDH13 OR4D6 MIS12 EREG GPR55 TGFA KSR2 NUMB GPR45 OR6J1 REEP1 TAS2R38 GRIN2A FGF22 FOXO1 CMKLR1 TNFRSF10B CSN2 OR5L2 CTNNB1 SYDE2 ASH2L RHOT1 PLPPR1 YWHAG OR10Q1 XIAP BTK KHDRBS1 CARM1 GRB10 DKK2 NCKIPSD GUCA1A EVC RAC1 CHUK OR4K14 CDK2 OR2T3 OR8D1 SPPL2B RHOBTB2 LATS1 HIST3H2BB RTKN RGS10 DLAT HGFAC PAFAH1B1 NPY5R HNRNPH1 AMHR2 WNT7B ADCY3 CCNT2 CYFIP2 NUP107 OR2B6 ARHGAP26 MAPK11 UBE2M IQGAP1 GNG7 SAV1 GSK3B CSK AHCYL1 FGF20 CAMK2A RHEB OR4A8 OPN1MW SSTR1 PDE10A TNRC6B PSMD2 KITLG FASLG TRAF1 NR5A2 CCL5 DYNC1LI2 FURIN OR6M1 WIPF1 SMAD7 ATP6V1D OR14L1P PPID PCSK5 GPSM3 OR10J3 BCAR1 NEDD8 OR8I2 PPP1R12B HTR1D GNG8 PDE8A OR2W6P GNAQ RAPGEF3 CUL1 ARHGAP6 GFRA4 YY1 RASGRP2 TAB3 RLN3 OR51J1 WDR19 COL3A1 OR2J3 RHPN1 OR2AG2 CDK5 SPTBN4 OR3A2 DUSP10 CCND3 OR51B4 GHRHR PLPPR3 VPS35 SAG PRKCZ HNRNPM FKBP4 PLCB3 PYGO2 FGF2 NTRK2 CASP2 MTA2 MAPK7 STAM2 OR5B2 CXCL11 AWAT2 PSMD13 OR8J1 HIST2H2BE CDKN2B NUP85 MARK3 ADGRE2 SKA2 ADH1A STAT3 IL6R OR1M1 STAT5A MYO7A CDON ARHGAP19 P2RY11 GPSM2 CDC20 PYY OR7G1 OR4K3 PLCB2 MT-RNR2 RBP4 GDI1 CDC37 PSMA8 GABBR2 PPP2R5C MCHR2 TACC3 TUBB2A MAPK4 JAK2 TAS2R8 ECE1 FZD1 OR6X1 FFAR1 SOCS3 VWF LRRK2 MYO9A VCL TUBA8 TFDP1 DHRS4 TRAF2 NCAM1 ARHGEF6 KIF18A OR3A4P PLCB1 RHOQ TNRC6A RXFP1 IGF2 PTH WDR83 PDHX IGF1 GDNF ARHGAP15 HSP90AA1 AP2B1 DGKB GRM8 ITPR2 OR13F1 FGFBP2 RING1 WNT9B RALBP1 EGR1 PTPRK OR52D1 PDE4B OR52I1 AVPR1A DUSP1 SOX7 WNT9A KIF5A OR2A7 ROR2 GRB7 WWC1 RGS20 ATP1B4 RDH8 AVPR2 F2RL1 RTN4 IKBKB PLA2G4A XCR1 NOX3 RHOC OR6B3 ADAM10 LAT OR1C1 IL5 HSD17B6 NPW OR2G6 OR5K1 PNLIP TNRC6C NOS3 OR1N2 PPBP CCNE1 OR1L6 PHB TLE1 OR1E3 RANGAP1 UCN2 RBBP5 COL4A2 PSENEN AVP OR52H1 COL9A2 INSL5 NEDD4L TRPC6 OR5AS1 SH3KBP1 RAF1 OR5H14 DNM1 RARG GNAO1 SSTR4 AHCTF1 RYK IHH INCENP NCBP2 MAD1L1 OR10J6P OR8B4 BIRC3 MKS1 CBX4 BIRC5 PHC3 OR5B3 OR7A5 HSPG2 TRADD FRK PSMB3 NOXA1 DUSP9 P2RY4 TLE3 ACTG1 SKIL EGF RICTOR RLBP1 ATP6V0E2 TAS2R46 HIST1H2BN OR1A2 TBXA2R NTRK3 IGF2BP1 GNAS PRKAG1 BRAP PPEF1 INHBA OR8K1 OR10T2 CNKSR2 CBX2 GREM2 DAGLB OR4C15 OR9A4 HGS JAG1 PMCH RASA2 GPIHBP1 CLIP1 GHSR PSAP NR2E1 OR8H2 LRIG1 CYFIP1 RGS1 KL CHD8 TAS2R16 ARPC4 OR2T27 PRKACB ADGRE3 OR2K2 OR11H7 OR6C65 GPR37 ATP6V0E1 OR2AJ1 GPR83 OR10R2 RHOA OR1K1 OR2T12 PREX2 CNR2 UBB HDAC5 MAPK8 ATP6V0D1 GUCA1C OR8S1 DGKD MAP2K5 GALR3 TSHB NRAS OR4K1 EIF4G1 CDKN1A OR8H3 GPHA2 HIST3H3 COL1A2 NMS DRD4 PDE6A OR52E8 RAB4A NTSR2 OR6N2 DHRS9 ACTN2 GPSM1 IL2RB LAMB2 SLC24A1 CAV1 RANBP10 PTK2B ARHGEF38 PHC1 DGKI PGF OR10S1 OR7A10 PPP3CC CENPQ POLR2A OR52I2 AGTR2 OR51T1 CALCR OR2T11 POLR2F ATN1 MCF2L SQSTM1 KNL1 CNKSR1 PSMA5 FST OR9A2 DGKH CSNK2B HRH3 FGF16 ANOS1 VANGL2 HRH2 CNR1 SCMH1 RPS6KA1 ADCY7 IFT122 STAG2 HDAC11 PTPN11 HIST2H2AA3 NMT2 CCL19 OR4C5 CRABP1 NRG3 CCKBR PTH2R PIK3CD DNM2 GNB1 TAS2R1 OR4C11 OR1J1 LAMC2 LGR4 OR1S1 BEX3 SRY CXCL13 P2RY10 FGA TAS2R50 DSN1 OR2G3 RIT1 PTPRU OR2M3 BDKRB2 OR14J1 ARHGAP42 TUBA4A OR8U1 COL9A1 ZFYVE9 AKR1C3 FRAT1 MYD88 PDYN OR51V1 AKT2 CLTC RACGAP1 IFT57 ATP6V1G2 CCNC RASGEF1A ARHGEF39 DNER CENPN MYB INSL3 PRKCI CRKL OR1D2 NCKAP1L CENPA CLASP2 ROPN1 SCT OR52N4 ARHGDIG LRP12 PRR5 WDR35 PMF1 OR4D10 OR10A4 OR1L8 H2AFB1 ACVR2B OR52N1 SUZ12 TAS2R7 OR5T2 ARRB2 PDHA1 GDF2 MDK NOTCH2 DYNC1I1 MAPK12 YWHAZ OR1Q1 SST PPP2R5A OR4P4 RGS17 GRM4 NPHP4 OR6C2 OR6P1 TUBA4B OR8G5 LEPR ALDH1A2 PLXNB1 CSF2RB DAB2IP OR2W3 CALCA PLCB4 OR2I1P PLEKHG5 RAPGEF2 EVL OR2A12 ARHGAP40 ITPR1 PTCRA STAG1 PTGDR OR6K3 LAMC3 DGKK ARHGAP30 GRM2 SPINT1 OR51D1 ARHGAP44 DUSP2 NMBR ARAP2 OR11H2 CAMK4 REEP3 ARHGAP28 OR6C4 MAF1 VIP OR2T29 OR14C36 RAG1 IER3 AKR1C4 OR4C3 OR2M2 MAPRE1 H2AFJ LHB OR52A5 USP9X FSHB TAS2R31 HTR2A ARHGEF4 CTNNBIP1 ABHD6 TCF7 BAD PIK3AP1 B9D2 PAK2 SPTBN2 CREBBP SSTR2 PPY NMUR1 CHD3 LAMTOR1 ARHGAP24 ATP6V1E1 H2AFV MC5R RARB ELMO1 OR4D9 GFRA3 CLASP1 CCK PRKCH TRIB3 RANBP2 OR4X2 PRKACA WASF2 ETV4 HDAC3 PROK1 DIAPH2 FGG BRK1 HDAC7 PPP1CA RXRA MCHR1 ZNF217 ARHGEF16 OR9G4 RHOD RTP3 RELA MKRN1 PROKR1 TAS2R42 PTGER3 ADORA3 PRKG2 MAP3K11 NOXO1 JAG2 PTH1R ROCK2 TGFBR1 ATP6V1C1 OR2C3 OR6K6 SFRP2 ARHGEF35 TJP1 MC2R HDAC8 GPR183 F11R ACKR3 PHLPP2 TRIM27 PDE6G FLRT1 NFATC1 RGS11 AVPR1B OR8D2 F2RL2 OR10G4 OR5J2 CCL4L1 STAT6 WIF1 OR8K5 NPB CXCR6 OS9 OR51E1 NUF2 COL1A1 A2M KIF14 GNRHR ELF3 RNF31 OR2T5 CDKN1B RGS7 PORCN FGD3 MAML1 OR52K1 RHOH FSTL3 MIB1 MMP3 SDC2 RARA LAMA1 WIPF3 PSMB10 OPRM1 IFT140 APLN CCL23 RDH16 ABL1 VAV3 OR4S1 OR2T4 MAPKAPK5 PXN NCK2 BRAF EEF2K OR1L3 GNA11 OR4F4 EPS15L1 HRAS MEF2A OR6B1 SMURF1 OR6C70 ELMO2 KNG1 IQGAP3 OR2G2 LAMTOR3 CSF2RA KANK1 TAS2R39 OR10J4 RAD21 OR5G3 FOS CCR3 TUBB4B GAL PKN3 PNOC FYN ATP6V0A1 PAK3 TSC1 PTGES3 CX3CL1 FGF8 OR5M9 ARHGEF33 MTNR1B NPFFR2 BCL9L PPP1R1B ZW10 SALL4 SRGAP2 TAS1R1 OR4C16 MAPK3 BMP2 RACK1 TGFB1 RAPGEF1 OR8U8 ACVR1C P2RY1 BTC BDNF ADORA2A PSMA7 OR4L1 OR56B4 NRIP1 ARHGEF3 RPS6KA3 MC3R GRIN2B OR10W1 OR6C76 OR51L1 E2F4 BDKRB1 IQCE USP4 PELP1 COL6A2 TUBA1A XPO1 OR5M11 OR52Z1 OR4Q2 IL17RD IRS1 NMUR2 EDN1 MAPK6 FAS SMAD1 ABI1 ST3GAL6 CCL25 HIST1H2BB KIF2A IL1RL1 MYH11 C3 OR2L5 PROK2 GPR39 PTBP1 ANXA1 IFT88 TAS2R14 OR10G6 OR56A3 GPC6 FLRT3 HES5 XK NLK ZWINT CDC42EP3 SRGAP3 OR12D2 ITPR3 DVL2 HTR6 FZD5 IL6 CCRL2 OPHN1 PDGFRB TAGAP LIMK1 IL2RA MST1 HIST1H3A OR52A1 ADM2 SEL1L DLL4 SMARCA4 RNF43 GNG11 HTR2B NCOR1 TBL1XR1 RDH14 CHN2 NOX1 OBSCN ALDH8A1 REEP2 TAS2R19 CDK4 QRFP POLR2D OR2H2 COL4A3 KIDINS220 DOCK7 OR2A4 CDK1 CAMK2D HDAC10 TAS2R13 RGS9 PCSK6 SERPINE1 OR4D2 PLPPR5 RPS6KB1 CORT NR4A1 CHRDL1 PRKAA1 MAGED1 RFNG OR52B2 OR1A1 HRH4 CXCL1 PTPN6 PTPN12 SPINT2 OR7D2 ATP6V1F AMOTL1 OR2T35 FGB TUBB6 IL1RAP TACR1 GPR68 PRKAG2 PIK3R1 BCL2 OR51B2 GRK4 RBBP4 LINGO1 OR51G2 CCDC88C LRP1 RPS6KB2 SH2B1 VEGFB UTS2 ADCY9 MOB1B PPM1A WNT4 LAMB1 E2F1 OR2AK2 GNB2 RGS2 PSMA4 WNT2B ATP6V1C2 MAPK1 SDR9C7 OR4K15 TNFRSF1A NRG4 OR8U9 NOTCH3 YWHAB RXRG ARHGAP12 OR8H1 RTP1 CBY1 GNAZ POU2F1 RANBP9 FGF5 KIF5B NUP37 ATF1 OR1L4 TFDP2 OR51A7 OR4C13 AGO4 PRKAR2B B4GALT1 FGF18 PSPN RHOV ABI2 OR13C9 HIST2H4A BUB1 OR5W2 PTGIR OR2T8 GRIN2D EPAS1 OR5H2 CSNK2A1 OR5AC2 GPER1 DZIP1 NFKBIA TLR9 PDK1 CDC42 CCR2 OR4K13 NCF1 CXCL10 OR7D4 WWOX CENPE OR2V2 OR8B12 OR11H4 RPS6 NCF4 OR6C1 RGS21 PRKAG3 GNG5 PSME2 OR52N2 SYK LAMTOR4 METAP1 CASP3 OR8G1 PSMD8 RUVBL1 OR10A2 OR8G2P CXCR4 CILP FGF23 COL6A6 GSK3A PTHLH VPS26A TNS4 CRK PRMT1 PDE4C OR4N4 DHH PTK6 CAMKMT BMPR1A PTGDR2 OR51I1 CYBB LAMC1 ARPC5 TAS2R30 ADCY8 GFRA1 BCL2L11 ARRB1 SRF SMURF2 PDHB OR2D3 PTH2 GNG2 PTPRJ KDM4C PPP5C SH2B3 PDGFRA RNF146 FPR1 CGN RRAGD RPS6KA2 GNGT1 ARHGAP32 TCIRG1 OR6C75 SPRED3 HBEGF TLN1 RBP2 IKZF1 ITGB3BP DLC1 POLR2C PF4 MUC20 PTGER4 SDC3 KBTBD7 TNKS OR2A42 OR2T2 ADAM17 SNW1 USF1 MECOM SPOPL THBS1 SMC1A CCND1 BAG4 ARHGEF19 KIF7 PTCH2 H2AFZ OR11A1 OR6C68 OR10G7 NMT1 SPTBN5 GNA14 CD80 HIST2H2AC DYNLL1 OR7G2 CBX6 PGR COL24A1 AGO3 FMNL1 MYL12B NDC80 MAPK14 FPR3 VAV1 ADRA1B SCRIB CCL28 OR5AU1 SDC4 GNB3 BAX TEC AKAP9 CXCL12 DYNC1H1 ITGAV ARHGAP36 TAS2R60 PSMA1 ARHGAP25 DUSP6 DTX4 CXCR5 LYN HDAC9 MAPK13 MDM2 OR4C46 RIPK1 ACVR1B GRP GLI1 OR2T33 OR52E4 OR13H1 OR4A5 OR1D5 LGR6 RHOU SFN CAMK2B TFF3 DUSP7 DGKZ FNTB SHC3 PIP5K1A RCOR1 NEURL1B OR52N5 SPTB LPAR6 OR13C4 GPR150 HIST1H2BH ITGA2 OR6Y1 GNB5 OR1F1 OPN3 CSNK1A1 GZMB RGS16 ERBB3 ATP6V0A2 RASGRF1 ICOS OR56A1 CDK8 OR6B2 FGF19 YWHAQ OXT FPR2 PPP2R5D NGF THBS4 LEF1 DEPDC7 OR5B12 OR2L2 PDGFA LEP TAAR5 SPC25 RXFP4 OR2T34 FBXW7 CD28 CRHR1 CPT1B FOXO4 OR5H1 RCC2 JAK1 SYVN1 UBC ADORA1 RGS18 MLN MMP9 CXCR1 SCTR AURKB IL6ST APOA4 NPY DGKQ HIST1H2BC NRTN GLI2 OTUD3 CTNND1 SSTR3 SSTR5 ERLEC1 OR2AT4 OR51G1 E2F5 ARHGDIA PHLPP1 LGR5 ADGRE5 MOV10 OR52E6 FZD2 OR2Y1 PDE7B LAMTOR2 OR10J1 ARPC1B RAB4B OR51A2 OR5R1 NOG AMER1 KAT2A FN1 OR8K3 STRADB KLC3 GTF2A1 TTC21B ADRA2A CER1 LATS2 TFF1 OR5AN1 TUBA3E OR6T1 RGS9BP KRAS OR5A1 ATP6V1B1 HSP90AB1 H2BFS OR10D4P ARHGAP20 PDK4 TNFSF10 OR11H1 RAPGEF4 NRP2 AGT NLN PARD6A PDE4A DLK1 FKBP5 AP2S1 OR7E24 TUBB4A HIST1H2BL SOCS1 TAAR9 ATP6V1G1 RBL1 TUBB3 RAP1A FGF6 AGTR1 APC MOB1A OR1E2 CDK9 SUCNR1 TAB1 CENPM MYLK ADCYAP1 OR8B8 TUBB8 SPP1 GNGT2 GCG PRKACG NPS GNAT3 PFN1 OR4Q3 SOS1 PLEKHG2 MGLL FLT4 BIRC2 ALDH1A1 DOK1 OR6K2 NCF2 GNA13 NUP160 MCF2 TBP COL6A5 REEP5 OR2T1 OR52M1 ARHGAP35 DERL2 PLK1 RAMP3 LAMTOR5 OR5V1 VEGFA MAPKAPK2 REST GPR4 C5 VAV2 SMAD4 NMU HCAR1 TGIF2 MEF2C RBX1 OR3A1 FOSB RASAL3 CYSLTR1 GNAT1 TNF OR5K2 SAA1 OR4N2 GPR17 CDH5 BTRC SUFU PDE7A KREMEN1 OR5T3 ARHGAP4 FGD2 ACTB FAM13A PDE2A OR1P1 OR2W1 GLI3 RPS6KA5 KTN1 OR10H1 MYH9 ADRB3 MYH10 UBA52 LFNG FZD9 ATF2 CASP10 PTGER1 HIST1H2BA DLGAP5 MTOR CITED1 C5AR2 FZD4 PKN2 ARHGEF10L XCL1 TEK THBS3 COL4A1 TAS1R2 PYGO1 COL11A2 EVC2 GPR31 HIST1H2BM CBX8 PRICKLE1 STRADA METAP2 RTP4 PSMB8 POLR2L TRAF6 NRG2 BCO1 GALR2 THEM4 CXCL8 OR4K2 AXL AKT3 PLB1 LAMA5 OR5T1 IL3RA TAAR2 NSMAF RHPN2 NEDD4 AR OR4M1 CXCL3 GATA3 CXCR3 TAS2R9 COL2A1 TYK2 TNKS2 CNTN1 GGA3 NRP1 RSPO4 OR4A15 PSMD6 RLN2 RPTOR STRAP ABR OR9K2 PSMC4 CXXC5 HIST1H2BD ARHGAP5 PEA15 S1PR2 IRS4 NDEL1 APP GFRA2 OR2A25 SNX3 OR5M10 WASF3 CRHR2 MEMO1 CASP8 ELK1 PPP2R1B SEC13 CCR10 UCN PLPPR4 PRLHR PIK3R3 CHD4 OR2D2 GRK3 GHRH OR51H1 OR6C6 KEL PHC2 OR5D18 GPC1 PSMB2 OR5P2 PSMD3 OR10AG1 ESR1 PLPPR2 HCRTR1 POLR2B OR14K1 OR11G2 PPP2CB DRAP1 MRTFA ARHGEF26 SKA1 S100B GPR27 OR10K2 RGR PSMB4 DUSP16 GIP NCK1 TUBB2B OR6Q1 OR51I2 OR10H3 S1PR3 ARHGEF25 INPP5B CDC42EP5 OR9G1 GTF2F2 RPE65 OR10H5 ARHGAP1 HIST1H2AC GRAP SCUBE2 OR14I1 FGF9 FCER2 AXIN2 OR2AG1 CDCA8 COL6A1 OR5I1 OR11L1 PSMD9 YAP1 STAT1 CFL1 OR10A3 CD19 OR4M2 RASAL1 PTAFR DLD ADCY6 OR2T10 PIK3R5 NTRK1 TAS2R40 POLR2G MST1R CENPT JAK3 OR52A4P OR2B8P TSHR GRM1 ADAM12 CDC73 ST3GAL3 WASL STAM GNG10 ARHGAP23 CHEK1 OR4K5 RASA1 YES1 PDE11A NCBP1 RRAGB ATP2A1 CCKAR PLG TAAR1 MC1R PSMB9 CLTA MTA1 CDC14A TP53 GCGR DYNLL2 SKP1 PTPRS DGKE CMA1 FGFR4 PRKAA2 OR10G3 HTR4 OR10AD1 MBD3 PIK3CA GNRH1 PKN1 ADCY4 TTR RGS22 PPP3CB FZD7 OR2H1 NUP43 SMAD5 FGFBP1 OR5AK3P OR4A4P PPARD CYBA CLIP3 FABP5 USP13 CCL4 DYNC2H1 SHC1 PRKCB FGD4 NET1 PAG1 GPC4 RAG2 P2RY14 OR2A5 IQGAP2 KALRN AXIN1 EDN3 OR51A4 ARHGAP45 PSMA3 ACKR1 OR5AP2 ESRP2 MATK SMAD3 KDM1A PSMD7 SH2D2A GRK5 FMNL3 LHCGR MED1 RRH LPAR1 NRG1 USP15 RASGRF2 PRKCE ARHGEF9 DHRS3 DAAM1 PTGER2 WNT5B KLC4 GAB1 OR52B6 GUCY2D OR1N1 HIST1H2BO OR5M8 RHOB FGF7 LAMB3 NPFFR1 PLXND1 OR4K17 THBS2 NUP98 HDAC6 CBL PIK3CG VIPR1 WWP2 ITGA3 ECT2 APOA1 CLPS COL9A3 OR2M5 HNRNPA1 RGS12 PLAT RBFOX2 RGSL1 KSR1 DOCK1 GALNT3 OR5AR1 BAMBI F2RL3 SH3GL2 PTPRO ARF6 FABP7 CTTN CCNT1 RALB PIP4K2A NAPEPLD WWTR1 PREX1 OR1I1 DLL1 OR2F2 TAS2R20 NPY2R NPY1R RBBP7 PSMB7 ARHGAP9 RCVRN GNG4 OR51S1 CCL21 FOXH1 CENPF FZD10 PSMD4 DAGLA HTR1E PMEPA1 TAS2R3 LRP8 OR10X1 PLCG1 OR9Q1 HCAR2 FLT3LG AMOTL2 CCR8 EBAG9 F2 LAMA3 WASF1 STARD13 FGFRL1 PTCH1 ECE2 OR2B11 OR52L1 TAC3 EIF4EBP1 OPN4 PRLH NUDC ACTR3 OR4D1 ATP6V1G3 ADGRE1 SRC GPHB5 KAT2B ITGB3 CASR MTMR4 ARHGAP8 HTR1A OPN1LW OR10H4 MAG APOA2 ITSN1 EPS15 MAP2K1 GHRL OR7A2P TNFAIP3 SOX13 PDE3A RTP5 NSL1 TNFRSF10A PSMD12 CDC42EP2 ATP6V0A4 ARHGAP22 RAP1B NCKAP1 AKR1B10 OMG TAX1BP1 OR2T6 HGF GAS8 STUB1 RNF41 GRB2 DUSP4 CENPU GRK1 DKK4 STK4 OR4E1 TGFBR2 OR5H15 PDK3 SKI GNAI3 P2RY12 PSMC6 NOTUM DYNC1LI1 ATP2A3 OR7C1 PPP2R5B MTNR1A APOC2 RGS6 OR2L13 CSNK1G2 OR10P1 ARHGEF10 OR4F6 TAAR6 COL5A1 ADRA2C LPL FGF17 TRH FNTA ARHGEF17 OR4A47 IGF1R LIMK2 RASGRP4 SGO2 OR4F15 BCO2 TAS2R10 JUND GNB4 OR5AL1 GNRH2 PSMD11 EZH2 FMNL2 FLT1 KHDRBS3 GPR37L1 GNAL FLT3 PSMB5 GMIP HIST1H2AD OR2M7 IL5RA OPRK1 GALR1 OR2L8 AMOT HSPB1 OR10D3 OR1J2 NOTCH1 PPP1R14A MFNG MIB2 GPR20 OR51Q1 PPP3R1 OR5D13 PSMF1 OR10H2 TAS2R41 CD86 OR4E2 CHRM2 NF2 EFCAB7 WAS TAS2R5 GPC3 GRM6 LDLR SGO1 AKAP13 OR2M4 LIN7B DNM3 RGS14 ATP6AP1 STK3 RDH5 RPS27 MAML2 ADCYAP1R1 CCR6 OR51B6 RPGRIP1L PSMB1 ATP6V1A OR9A1P SP1 OR8J2 ATP2A2 CXCR2 LEO1 ATP6V0C KIF3A VIPR2 RXRB UBE2D3 CXCL5 FUZ OR1F12 MET CHD1 MAPKAPK3 OPRD1 FKBP1A KLB TUBA1C MAP3K7 KIF2B GRK2 JUP SMPD3 GTF2F1 PDK2 OR3A3 ARHGEF2 EDN2 INSR ERBB4 LCK OR5L1 HRH1 RGS4 VEGFD ADCY5 WNT7A PRKCG PRKCA PPP2CA ARPC2 ARHGAP11B POLR2H GRPR RASGRP1 CRHBP PRDM4 LRP10 MAPKAP1 RGS3 FGF10 SPC24 GLP2R RBP3 WIPF2 PIK3R6 OR2J2 PTPN18 SOX6 OR6C3 RGS5 OR6N1 TIA1 RASA3 OR5K3 CCR4 KAT5 SDR16C5 OR2W5 PDE1B CYP26B1 LPAR2 SH3GL3 AATF CENPO OR13A1 TAAR3P RBCK1 EIF4B SYNGAP1 ARHGEF15 PSMA2 NFKB1 CHRM4 USP21 GAS1 GPR84 POLR2J EGFR WNT5A OR10Z1 OR56A4 PSMD10 PTPN1 GPR35 HEYL IL33 OR5H6 ATP6V0D2 PDE6B GATAD2A YWHAE CX3CR1 CXCL6 DNAL4 MKNK1 APLNR PSMB6 S1PR5 RBPJ FZD6 DRD5 ESRP1 CTSD SPRED1 LAMA4 GLP1R MC4R RGS8 TJP2 DGKG COL5A3 CD55 RHOT2 OR4C6 KNTC1 FES MYO9B NEFL RETSAT OR2F1 CCNK IL3 MAD2L1 DACT1 OR4A16 OR51E2 OR2Z1 TAC1 OR10AC1 CALCB FFAR4 TCF7L2 SPRY1 PRKAR1A ABCA4 TACR3 NDE1 STRA6 OR4B1 OXTR OR4F17 OR52E5 DLG4 GAST CCR9 PPP1R15A DIAPH1 SNAI1 ATP6V1E2 XCL2 CPT1A SHH ARHGDIB ADRB1 FLNA DRD1 HNRNPF PCP2 FGFBP3 PDE1C CCL1 RDH10 GNG3 POMC PML GATAD2B DKK1 CCR5 NMB OXGR1 PIP5K1B PDGFD RAC3 TAAR8 CXCL2 OR5A2 NTSR1 WWP1 HIST1H2AB SHARPIN OR14A2 DEPDC1B GUCA1B STARD8 FOXA1 SPTAN1 CENPI ARPC3 NOTCH4 SLC38A9 RHOG CRH ARAP3 GAB2 OR51M1 RSPO1 OR52W1 TMED2 NELFB ADRA2B KLHL12 INHBB PBX1 HTR1B DUSP3 HDAC4 BUB3 OR7C2 IKBKG SYDE1 PTK2 RGS13 DGKA MAML3 CNGA1 S1PR4 RXFP3 S1PR1 PSMA6 LPAR5 EPN1 SOST ARHGAP18 OR1E1 RRAGC OR2S2 OR5C1 OR13C2 SOS2 CDH1 PRKAR1B ADRB2 RSPO2 GRIN1 INS WNT1 OR4F16 PTPN2 POFUT1 GRM3 RGS19 SPOP ULK3 USP7 GPR161 FGF3 OR4X1 TAS2R4 CXCL9 PIP4K2C PARP1 RASA4 PDE1A PRKCQ COL11A1 OR2L3 OR10K1 GPR18 ZNRF3 PTPRA RHOJ HTR1F ACVRL1 OR51F1 BAIAP2 ARAP1 SCAI GRM7 OR10A7 ANGPT1 SPRED2 CHRM5 LRP6 WNT8B MEN1 NTF4 PAQR3 C3AR1 RAB6A NPFF GUCY2F ATP6V1H TBL1X OR6V1 WNT11 ADCY2 DISP2 RBP1 PTEN INTU ARHGEF18 OR4D11 ITGB1 ARHGEF37 LPAR3 AP2M1 MADD PROKR2 KDR PSMB11 FSHR DYNC1I2 AMH SOX4 RDH12 YBX1 RALA CDK5R1 HCAR3 NCOR2 LRP2 CDC14B OR13G1 NR3C1 CRABP2 CYP4V2 DTX2 BMP10 GPC2 ACVR2A CAMK2G TNFRSF10D TRAT1 DRD3 PIK3CB GRK7 CTBP2 GNA15 LRAT SEPT7 APH1A CAB39L OR13D1 GNG12 CIT ADRA1D ERBB2 STK11 COL6A3 OR2B3 WNT16 NTF3 RRAGA GRK6 ARHGEF40 FRS3 USP34 OTUD7B PPP2R1A GPR132 BUB1B RAC2 USF2 ACKR4 ACTA2 HTR2C BMPR2 CCR1 TAOK1 OR2B2 ATP6V0B VRK3 APOB PIP5K1C IRAK1 OR51B5 GPR65 RNF2 GABBR1 OR52K2 SDC1 TUBB1 ARHGEF5 TRIP10 AGRN PDPK1 CUL5 NF1 COL5A2 RTN4R VEGFC
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Hierarchy Landscape

The following plot represents the hierarchical landscape of 'Signal Transduction'. The hierarchical tree allows to click on the pathways with children (black border) and continue the exploration. All nodes are colored by their source (click on the map for the legend) and cross-link to the original pathway page.

Sub-Pathways

About

ComPath is developed and maintained in an academic capacity by Daniel Domingo-Fernández and Charles Tapley Hoyt at the Fraunhofer SCAI Department of Bioinformatics. This web application relies on data loaded from KEGG, Reactome, and WikiPathways Restful APIs, as well as MSigDB. More information here.