Adaptive Immune System - Pathway Page
Name Adaptive Immune System
Resource Reactome
Genes BLMH CARD11 IGKV1-17 DET1 CUL3 RNF6 CD274 COL2A1 PSMC1 LAT YWHAB KCTD6 BTBD6 CAPZA3 IKBKG AP1M1 TIRAP REL MAP3K8 PPP2R5B PTPN22 PSMA2 ASB9 KLHL9 RLIM SPSB2 UBR2 PSMB5 LILRB5 IGHV1-46 FBXO15 PSMD11 UBE2N FBXO41 ELOB CD1B UBE2D3 LRRC41 PRKCB IFI30 B2M KLRG1 IGHV3-30 RASGRP3 RNF111 DNM2 RBCK1 BTN3A1 KIR2DS1 AP2M1 SEC23A TUBB4A PPP2R1A UBE2D4 VAV1 TRAV8-4 PSMB11 HLA-DOB ZNRF2 PPP2R5E UBE2V2 WSB1 HLA-DRB3 KIF2A IGLV2-8 SEC24A UBE2E2 ANAPC5 NEDD4 MTOR AKT2 MKRN1 HSPA5 CBLL2 LAIR1 KLHL13 ANAPC4 SEC24D AP1G1 TUBB6 KIF3A UBE3A HLA-DRA LAIR2 ITPR2 ICAM3 CUL7 ERAP1 TUBA1C AP1S1 PSMB8 FBXL14 CD4 UBA5 FBXW4 ASB1 BLK FBXO31 LTN1 NFKB1 SELL ASB10 RASGRP1 IGKV2-28 CTSL RNF19A BTN3A3 CHUK TRIM50 IGKV1-5 CD247 TUBA4A C3 FBXL7 AP2B1 RNF4 SIGLEC12 SEM1 PDIA3 LILRB1 ICAM4 CD8B TUBB8 NCF1 HLA-DRB4 PJA1 PLCG2 LILRA4 CLTA LYN ASB12 FBXW8 CD22 TRIM4 NFKBIE AP2A1 CD3G TRBC1 SIGLEC9 IGLV7-43 FBXL13 CD74 CD40 NPDC1 FBXL20 FBXO17 TRIM41 ITCH UBE2C BTN1A1 KLC4 ANAPC13 KIF22 IGHV3-9 CALR PPP3R1 CDC20 UBE2E3 IKBKB PSMB2 KIR2DL1 PIK3R3 IGHV1-2 RCHY1 ICAM2 PSMC5 ITGB2 RNF217 NCR2 IGLV3-19 HLA-DMB HLA-DPB1 PDCD1 CD34 HLA-DQA2 CLEC2D FCGR2B SMURF1 RAF1 PSMA3 FBXO30 CD19 TRIM11 KBTBD13 NFKBIA TUBA3E RAPGEF3 CTSC DNM1 SEC61G PRKCQ PSMD10 IGHV4-59 UBE2U FBXO6 KLHL41 JAML CD300E HECTD3 TAP2 PPP3CB UBE2J1 KLHL3 LNPEP IGHV3-11 NFKBIB PPP2CA RNF123 TUBAL3 UBE2A UBE2K UBE2F TNFRSF14 RAC1 PIK3R1 KIF15 IGLC1 DYNC1H1 ASB5 UBR4 KLC2 KLHL11 KIF3B PSMA1 CCNF PILRA TLR4 TRAV29DV5 TPP2 PSMD6 AKT1 ASB17 CD96 CDH1 AHCYL1 PSMB9 HLA-DQB1 KIF26A IGKV1-16 PAG1 MYD88 ASB18 HERC4 PJA2 ULBP3 IFITM1 SIGLEC1 UBOX5 TAP1 RNF144B PRKG1 NFATC1 ASB14 CTSO SIAH2 TUBB3 HLA-A PTPN6 RAP1GAP YES1 LILRB3 GAN PSMB7 NCF2 FBXO7 TRIP12 AP1B1 TRPC1 PDPK1 TRIM9 IGKV1-39 LCK KLC1 TRIM63 IGHD NCK1 TRAF6 FBXO22 UBE2V1 FBXL4 CLEC4G IGLV3-21 UBE2M RPS27A PAK3 ANAPC1 KIF11 DCTN4 SH3RF1 SPSB4 TUBB1 STUB1 ATG7 HLA-DRB5 BTBD1 CD33 CTLA4 LILRA5 IGLC6 CDC26 TRIM39 CD40LG RAPGEF4 DYNC1LI2 CAPZA2 BTNL9 NCR3 TRIM32 CANX CTSD IGKV2-29 LNX1 SKP1 PPP3CA IGHV3-13 ITPR1 KIF18A RAP1B PSMC2 ZNRF1 CRTAM PSMB6 ITGA4 CD209 PSMD3 LCP2 ASB13 UBB CD300LG BTN3A2 PAK2 UFL1 UBE2J2 PPP2R1B ANAPC7 ELOC TAPBP PIK3CB CD79B CSK CD28 BTK FBXL19 LY96 HACE1 RNF115 ICOSLG INPP5D LMO7 HERC2 LILRB4 CD14 IGLV1-51 SH2D1B RNF220 SPTBN2 RELA IGKV3-20 BTN2A1 UBE2D1 ULBP1 DTX3L CTSH RICTOR CTSE KIF5B FBXO40 UBE2Q1 CD160 KIF23 NCF4 FBXL16 FBXW7 DCAF1 CYBB CD86 UBE2D2 COL3A1 CD1A KCTD7 CD200R1 IGKV1D-16 ITGAL NRAS COL17A1 MLST8 PSMC6 IGKV2D-30 ZBTB16 TREML1 HERC1 ANAPC10 SIAH1 IGKV2-30 FBXO32 PRR5 CUL1 FBXL22 PPP2CB MYLIP RNF126 RNF182 IGKV1D-12 PSMB3 LAG3 CD300LB FKBP1A UBE2G2 UBE3D NCR3LG1 AP2A2 PSMD5 KLHL42 PIK3CD TREML4 ZAP70 FBXO44 RNF130 FBXO4 UBE2O UBE3C MAPKAP1 PSME2 UBE2Z FBXW12 SEC22B VAMP8 IGLV2-14 UBE2L6 HLA-H NFATC3 UBC IGKV3D-20 ORAI2 TLR2 AREL1 PSMA7 KLRC1 ARIH2 PAK1 LILRA1 DCTN5 IGKV1D-39 KIR2DL3 PIK3AP1 THOP1 IGKV2D-40 CD80 KBTBD7 TRBV7-9 TUBB4B FBXW5 IGLV1-44 COL1A1 FYN HLA-E BTNL2 CD300LD PTPRC PPP2R5A PSMA5 HRAS HLA-B ITGB7 HLA-DMA FCGR1A ITK SYK IGKV1D-33 TRIB3 UBA7 IGKV3-11 PSMD7 RILP FCGR3A PSMB1 CDC34 PSMA4 SEC61B UBA1 AP1M2 IGLV6-57 PVR CD226 PIK3R2 ITGAV LILRA6 TUBA8 CAPZB UBE4A IGLV1-40 ICOS CDC23 RBX1 UBE3B UBR1 UBA52 HLA-DOA HERC3 KLHL25 ACTR10 SEC13 UBE2H KIR2DL2 TRAC EVL IGHV4-34 SEC61A2 PPL SIGLEC7 FBXL8 KIF4B TLR1 FBXW11 UBAC1 IGLV3-25 DAPP1 PRKACA ANAPC2 SLAMF7 LILRB2 VHL KLRK1 RAET1E CD3D TYROBP WWP1 BCAP31 COLEC12 FCGR1B CD8A FBXL3 KLHL22 TRBV12-3 KIF3C BTN2A2 LILRA3 RIPK2 AP1S3 KEAP1 SHC1 CDC42 KIF2B MEX3C KIF4A IGLV2-11 ASB4 TUBA1B CYBA CD300C PSMD9 RNF34 ICAM1 FBXO21 IGHV1-69 PRKACB ICAM5 ASB15 STIM1 PPIA HLA-DRB1 ASB2 KRAS BTLA CDC16 DCTN3 NEDD4L SH2D1A CLEC2B OSBPL1A AP2S1 UBA6 TUBA1A MAP3K7 TRAV19 SEC24B NCR1 RNF19B SPSB1 STX4 RNF7 KLHL21 TREM2 DYNC1I2 FYB1 PSME4 SEC61A1 HLA-DQB2 GLMN HLA-DPA1 MICB CBL IGKV5-2 IGHV3-53 CTSB IGKV4-1 PILRB SLAMF6 FBXW10 LRSAM1 TUBA4B IGKV1-12 SRC YWHAZ TRAF7 CAPZA1 IGLV2-23 KIR3DL1 KBTBD8 CUL5 FBXO27 BCL10 SOCS1 CD207 GRB2 NPEPPS HECTD1 IGKV1-33 SIPA1 DZIP3 HERC6 RNF114 KIF20A HLA-F TRIM37 RAP1A TAB2 RAB7A CD79A CD101 ASB3 DYNLL2 KIR2DL4 RACGAP1 CTSK RNF25 IGHV2-5 CUL2 DCTN1 PSMB10 RNF41 CTSV CD300LF LONRF1 KLRD1 MGRN1 MALT1 VASP PPP2R5D CD99 CTSS KIR2DS2 CD300A NFATC2 UBE2B PSMF1 PSMD4 CALM1 VAMP3 SIGLEC8 GRAP2 SH3GL2 LRR1 UNKL VCAM1 PPP2R5C COL1A2 MADCAM1 UBE2S CENPE IGLV3-27 TRIM71 TRIM36 NECTIN2 BTNL8 FBXL12 ACTR1B UBE2R2 IGHV3-48 PSME1 DNM3 CTSA ITGB5 ERAP2 SIGLEC10 TREML2 OSCAR ASB11 FBXO2 FZR1 DCTN2 ITPR3 CDC27 KLHL5 CD1D HUWE1 SMURF2 PTPN11 FBXO9 CBLB ASB6 PRKN FBXL18 ANAPC11 CXADR IGLC7 RNF138 CD3E ASB8 TREM1 HECTD2 AKT3 MAP3K14 TRAIP TUBB2A UBE2Q2 HCST SAR1B IGHV2-70 UBE2E1 KLHL20 ASB7 XDH KIF5A UBE2G1 FBXW9 ITGB1 SFTPD LGMN KBTBD6 CLTC HLA-C PSMA8 PTPRJ PSMD1 ARF1 UBE2W PSMD13 PSMD2 PSMC3 RNF213 CTSF IGHV3-23 CD200 IGLV3-1 HLA-G TUBB2B ENAH FBXL5 IGHV4-39 TRIM21 SIGLEC6 DYNC1I1 KLHL2 KLRF1 TLR6 PRKACG GLYCAM1 PLCG1 IGKC RBBP6 SKP2 CD36 FBXL15 DYNLL1 KLRB1 CD81 UBE2L3 RAP1GAP2 DYNC1LI1 PIANP FBXO11 ACTR1A PIK3CA KIF2C SIGLEC11 IGHV3-7 HLA-DQA1 FBXW2 IGLV1-47 SOS1 RNF14 LILRA2 PSMC4 HECW2 SOCS3 SEC31A AP1S2 TRAT1 MRC1 HERC5 SEC24C MIB2 KIFAP3 TRIM69 THEM4 IGKV3-15 KLC3 FBXL21 IGHM SH3KBP1 BTRC PSMB4 PSMA6 DCTN6 KIR3DL2 MICA BLNK UBA3 PTEN SNAP23 SIGLEC5 MRC2 IGHV3-33 PSMD8 PSME3 ASB16 PSMD12 PDCD1LG2 PSMD14 RASGRP2 IGKV2D-28 FBXO10 CD1C WAS ORAI1
Size 826
Hierarchy Landscape

The following plot represents the hierarchical landscape of 'Adaptive Immune System'. The hierarchical tree allows to click on the pathways with children (black border) and continue the exploration. All nodes are colored by their source (click on the map for the legend) and cross-link to the original pathway page.

Sub-Pathways

About

ComPath is developed and maintained in an academic capacity by Daniel Domingo-Fernández and Charles Tapley Hoyt at the Fraunhofer SCAI Department of Bioinformatics. This web application relies on data loaded from KEGG, Reactome, and WikiPathways Restful APIs, as well as MSigDB. More information here.