Adaptive Immune System - Pathway Page
Name Adaptive Immune System
Resource Reactome
Genes MICA CD300LD CD1B TUBB3 YES1 ICAM2 IGKV2-30 TRAT1 HLA-E HECTD3 PSMD10 TUBAL3 TAB2 SIGLEC9 FYB1 DET1 LGMN PAK3 PSMD9 PRKACB UBE2O AP2M1 SIGLEC12 UBE2S LAG3 ASB10 LILRA3 CD300LF TRIP12 TRAC TRIM32 NFKBIE KBTBD8 PIK3R2 IGKV1D-12 FBXL12 NCR1 AP1S3 TLR4 SOCS3 FBXO9 MADCAM1 UBE2N RNF41 ORAI1 UBE2G1 CD300A TAPBP SMURF1 TUBB8 RNF19B TLR2 RNF123 HLA-DRB1 PTEN PIK3CB BLK DYNC1LI2 CD14 HLA-G LRR1 FBXO27 ANAPC11 BLMH IKBKG ICAM3 IFITM1 IGKV3-20 BTNL9 SPTBN2 IGLV1-47 FBXL7 SEC23A RILP UBE2C CSK FBXO30 PSMA7 ITGB1 RBX1 KIR3DL2 IGLV2-14 PRKN CTSS HECTD2 UBE2D4 CXADR FBXW8 PSMD1 SEC22B PAG1 PIK3CD UBR4 KLHL20 HLA-DQB2 BCL10 RNF130 LILRA6 RNF126 RLIM TRIM39 TUBA1A BTN2A2 PRKG1 SKP1 PRR5 LYN FBXL14 DAPP1 PPP2R1B PSME3 UBE2Q2 CRTAM TRIM41 NCR3LG1 PIK3AP1 KIF4B IGKV3-11 LILRA1 DCTN5 BLNK RCHY1 CDC26 FCGR2B TRBC1 IGLC1 FBXW5 NFKBIA COL1A1 TRAIP IGHV4-39 KRAS CBL HLA-DQA1 IGHV3-30 TRIM36 BTN2A1 IGHV3-11 IGHV4-34 DYNC1I1 RNF213 FBXO40 SIGLEC11 HLA-DRA ASB5 CTSE IGHV2-5 IGLV1-40 UBOX5 TRIM50 IGLV2-23 TUBA4B ASB1 KLRG1 UBE2E3 FBXW9 CD81 BTNL8 PTPN22 PPP2R5E RIPK2 UBE2J1 PPP2CA SEC24D AKT2 PSMB5 FCGR3A NEDD4 KLHL13 IGLC6 TREML2 SEC24B IGHV3-48 ACTR1A UBE2Z IGKV3-15 JAML SIPA1 ORAI2 CLTA ITPR3 TLR6 NCR2 RNF25 GRAP2 CD40LG ITGB7 PPP3CB PDPK1 CAPZA1 UBE4A SEC31A NFKB1 CD22 KLHL9 RICTOR MIB2 TRIM69 COL17A1 TUBA1C CDC34 SNAP23 AP1B1 CD207 KIF26A PSMB7 BTN3A1 TAP1 CUL2 RNF182 CD80 VASP SIAH1 PSMC3 TRIM11 FBXL19 IGLC7 IGLV3-19 PSMD2 TIRAP CD200 CD200R1 IGKV5-2 TRAV8-4 LAT IGLV1-44 ICOS PSMD12 GLMN CARD11 DNM2 ZNRF1 ULBP1 STIM1 ASB14 PSMB11 CD3E ASB16 RNF6 HLA-DPA1 TRIM37 TRIB3 PSMB2 CDC23 LILRA2 FYN TUBB4A IGHV1-2 KLHL25 PPIA ASB11 TRBV7-9 FZR1 IGKV2D-30 B2M TREM2 MAPKAP1 LILRA5 CD34 PSMD4 KLC2 TRAF6 PSMA3 RAP1B FBXW4 MYLIP ITPR1 PSMA4 CUL3 CD28 UBE2D2 KLHL3 PAK2 SLAMF6 CD36 LCP2 MKRN1 PPL LAIR1 SH3GL2 FBXW2 THOP1 LILRB3 MALT1 ARF1 YWHAZ CD226 PPP2R5D IGKV3D-20 MAP3K7 SHC1 TRIM4 SIGLEC7 IGKV1-17 GAN PTPN6 TRIM21 PLCG1 ASB7 PSMD7 CD300E ARIH2 KLRF1 IGLV3-27 HSPA5 CTSH PSME2 CHUK KIF3B IGKV2D-28 FBXL13 ZAP70 PDCD1LG2 FBXL8 PSMB1 CD3D ASB12 KIR2DS2 ITGAL INPP5D ASB3 KIFAP3 KLRD1 RAB7A RAET1E SOS1 CDC27 NFATC3 HLA-DOA SAR1B CDH1 TNFRSF14 UBE2L3 PSMA5 UBE2B DNM3 PILRA RNF19A IGLV7-43 IGHM CENPE KIF20A SH3RF1 WSB1 MRC1 VAMP8 IGLV3-25 TUBB4B TREML1 LTN1 C3 CD1A ASB17 TUBA1B IGKV1-33 FBXO7 PIK3R1 KIF3A STX4 HERC4 KIF2A SEC61A2 KBTBD13 CD1D BTBD6 CTSV TRBV12-3 PSMD11 PSMB10 SIGLEC5 MAP3K14 RNF144B CD33 MLST8 PIANP FBXL21 LAIR2 KIF5B KCTD6 ICAM4 IGKV4-1 HRAS IGHV3-23 KIR2DL1 ASB4 COLEC12 ANAPC2 PSMA6 DYNC1I2 NPDC1 RNF114 HERC5 FBXL3 OSCAR ITGAV SEC13 PSMB6 NCF2 DTX3L STUB1 ZBTB16 DYNC1H1 LY96 ITGB5 UBE2J2 TRPC1 KIR2DL3 CD247 RAPGEF3 CD74 TUBB1 KIF18A PRKCQ IGLV3-21 CD300LG KEAP1 CUL1 UBAC1 UBE2H HERC2 CDC42 PSMC1 AP1S1 LONRF1 IGLV2-11 AP2A1 PIK3CA CUL5 HERC6 KIF23 RNF14 CCNF PSME4 HCST PRKACA RAF1 UBB CTSL UBE2L6 PSMA2 ERAP2 ITGA4 IKBKB HLA-F VCAM1 WAS RELA SFTPD UBE2M IGHV4-59 LILRB2 ITGB2 CDC16 FBXL5 PPP2R5A VAV1 CD101 KIF11 IFI30 BTN1A1 MAP3K8 KIF2C CD160 HLA-DOB MTOR BTN3A3 ANAPC5 UBE2K MICB TUBA3E IGLV3-1 ATG7 PTPRC SH2D1B LRRC41 CD79A ANAPC7 IGLV2-8 NFATC2 BTN3A2 SIAH2 HLA-DPB1 ELOC FBXO6 TUBB2A CD300C HLA-B SIGLEC6 FBXO17 UBE2E2 PTPN11 CTLA4 HLA-H KLHL11 BTBD1 HLA-DQA2 TRAV19 MEX3C PDCD1 KLRC1 CYBA KIR2DL2 IGHV3-9 KIR2DS1 HUWE1 PSMD13 PSMB4 AP1G1 LILRB5 DCTN1 NECTIN2 TUBB2B CLEC2B PPP2R5C IGKV2-28 FBXO2 PJA1 PSMD3 SH2D1A FBXO31 TYROBP LCK CDC20 KLHL21 ASB6 AP2S1 LILRB1 IGHV1-46 IGKV1-5 UBA7 CTSF HLA-DRB4 KLC1 UBA52 PSMA1 PLCG2 SIGLEC1 PSMF1 SPSB4 CALR CD209 CD1C RACGAP1 ICAM5 VHL PSMB9 HACE1 TREML4 PSME1 OSBPL1A UBA6 SOCS1 NFKBIB IGKC BTK KLHL41 VAMP3 SEM1 RBBP6 CTSD TRIM9 RNF7 SKP2 FBXO22 PSMD5 ANAPC4 CTSB UBR1 KIF15 CBLB LNX1 NFATC1 TRAV29DV5 NRAS PIK3R3 FBXL18 CD274 PSMD6 AKT1 PSMB8 CD8A UBE2E1 UBE2A RAPGEF4 KIR2DL4 RAP1GAP FBXO10 BCAP31 RBCK1 KBTBD7 UBE2Q1 ASB15 UBA3 CD300LB RNF115 ANAPC10 FBXO41 KIF2B PJA2 PPP3CA SIGLEC8 EVL FKBP1A RNF34 UBE2G2 DYNLL2 TUBA4A SRC HECTD1 UBR2 KLRK1 SEC24C KLC3 KLRB1 ELOB PPP2R1A CD99 PVR ACTR10 ASB9 FBXL20 HERC3 TAP2 AKT3 UBE2R2 PSMC4 IGKV1D-33 REL FBXO44 RNF138 KLHL2 ASB2 ERAP1 ACTR1B PSMA8 SEC61A1 CTSA CTSO FBXW11 DYNLL1 CBLL2 MRC2 RPS27A HLA-C SPSB1 IGKV1-12 KCTD7 PDIA3 IGHV3-53 SEC61B FBXO21 ANAPC1 LILRB4 SYK KIF22 IGHV3-33 PPP3R1 PILRB FCGR1A CD40 PPP2R5B KIF4A COL2A1 ASB18 HERC1 HLA-DMB NPEPPS PSMD8 FBXW7 SEC61G HLA-DRB3 DNM1 DYNC1LI1 CLTC RAP1A AP2A2 XDH TRAF7 PSMD14 CD96 DCTN3 SIGLEC10 ASB13 LMO7 WWP1 CD3G NCK1 CLEC4G IGHV1-69 NEDD4L RAC1 TRIM71 IGKV2-29 CD8B UBE3D UBE2D1 UBE3C FBXL15 BTNL2 MYD88 KLHL22 UBE3A IGHD UBC CD86 NCF1 CANX PRKCB CLEC2D UBA5 TLR1 NCR3 IGKV2D-40 RASGRP3 AP1M2 FCGR1B UBE2V2 IGKV1-16 UBA1 IGHV3-13 KIF3C PTPRJ SEC24A IGLV1-51 PSMC5 FBXO15 CTSC ASB8 MGRN1 HLA-DMA FBXL4 BTLA PSMC2 FBXO4 KLHL42 CTSK KIR3DL1 PAK1 TPP2 IGHV2-70 HLA-DRB5 RNF220 FBXO32 SLAMF7 FBXW10 FBXL16 NCF4 KIF5A ENAH LNPEP CALM1 CYBB DCTN6 SMURF2 FBXW12 FBXO11 COL1A2 CD19 UBE2V1 FBXL22 IGKV1-39 AHCYL1 ITCH TUBA8 DCTN2 KBTBD6 HLA-DQB1 LILRA4 AP1M1 ITK IGKV1D-16 AP2B1 LRSAM1 ANAPC13 BTRC CD79B AP1S2 DZIP3 CAPZA2 HLA-A UFL1 CD4 SH3KBP1 KLC4 UBE2D3 IGKV1D-39 GRB2 UNKL HECW2 KLHL5 PRKACG COL3A1 DCAF1 YWHAB ZNRF2 UBE2W PPP2CB RNF111 RASGRP1 GLYCAM1 ITPR2 SELL ULBP3 RNF217 PSMB3 CUL7 SPSB2 THEM4 UBE2U RASGRP2 TRIM63 UBE3B AREL1 CAPZA3 RNF4 RAP1GAP2 DCTN4 ICAM1 UBE2F PSMC6 ICOSLG IGHV3-7 IGLV6-57 TUBB6 TREM1 CAPZB
Size 826
Hierarchy Landscape

The following plot represents the hierarchical landscape of 'Adaptive Immune System'. The hierarchical tree allows to click on the pathways with children (black border) and continue the exploration. All nodes are colored by their source (click on the map for the legend) and cross-link to the original pathway page.

Sub-Pathways

About

ComPath is developed and maintained in an academic capacity by Daniel Domingo-Fernández and Charles Tapley Hoyt at the Fraunhofer SCAI Department of Bioinformatics. This web application relies on data loaded from KEGG, Reactome, and WikiPathways Restful APIs, as well as MSigDB. More information here.