Adaptive Immune System - Pathway Page
Name Adaptive Immune System
Resource Reactome
Genes SEC61G ASB12 PIK3CA DAPP1 UBE2F KIR2DL1 CD40 KIF5A TRIM4 SIGLEC7 IGKV3-15 ITGB7 HECTD1 FBXL20 FBXW10 RAB7A FBXO27 PPP3CB IKBKB UBA5 AP1S1 BCL10 BTN3A2 KIR2DL4 PTPN6 FBXW11 HLA-DRA CYBA LAT AP1M2 LONRF1 UBE2R2 SHC1 AKT1 TUBB6 PRKCB SIGLEC8 PAG1 FBXO17 PIK3R1 FBXW12 UBE2D1 CD14 UBE2O FCGR2B ASB16 CD3E LILRB3 PSMD1 TREML4 PVR NEDD4L PLCG2 PSMA3 RASGRP3 SH3KBP1 RAF1 MRC1 DNM1 PAK1 PSMD7 FCGR3A FBXL15 RNF130 HLA-B SEC24B KLHL42 ARIH2 CDC34 PSMA4 COLEC12 MICB PPP3CA RPS27A ITK HECTD3 LILRA6 ASB11 KLC4 GRAP2 FBXW5 HLA-DMB BTN3A3 UBE3C PPP2R5E NCR1 YWHAB DCTN1 PDCD1LG2 KIR3DL1 PSMB3 CBL SELL FBXL22 KIF5B FBXO11 IGHV2-5 SPSB1 IGKV2D-40 UBE2Q1 ASB17 RICTOR PIK3R2 UBE2D2 TUBAL3 ICAM2 MLST8 RAP1GAP2 FBXO30 HLA-DPA1 KIF3B BLNK AP1S2 IGLV1-44 TRIM9 UBR4 SH3GL2 KCTD6 IGHV1-46 XDH NFKBIA CAPZA3 PSMD5 CDC42 CD247 ENAH HERC5 NCF1 IGLV3-1 TPP2 CENPE FBXW2 FBXL21 TNFRSF14 IGKV4-1 PSMB7 NCF4 LAIR2 PSME2 SYK UBR1 NCR2 KLC1 HLA-DRB4 IGKV1-12 PSMD8 KIF4A RILP NPDC1 UBE2C PSMD4 SEM1 PRKACB UBE2L3 IGHV1-2 IGLV2-11 RNF115 RNF182 PLCG1 IGLV3-25 IGLV1-51 IGHV2-70 LRSAM1 DCTN2 CD79B PDIA3 IGHV3-11 ITGB2 UBB MGRN1 CYBB TRIP12 UBE2Z TUBA1B HLA-DPB1 LAG3 IGLV3-27 NRAS BLMH CD209 SRC FBXL16 KIR2DL3 HERC3 UBE2K TAP2 SMURF2 COL1A2 VAMP8 PTPRJ HLA-DQB1 CD8B IGKV1-33 KLC2 UBE2S CD40LG LILRB1 PIANP CD300LD BTBD6 CD300LF TRIM37 HERC4 PSMD12 FBXW9 HERC6 RAP1B FBXO32 CD160 LILRA2 KBTBD6 SEC22B HERC2 CD274 FBXO41 HERC1 KBTBD7 STUB1 RNF41 GRB2 CALM1 DCTN6 SPSB4 RNF144B RNF14 LILRB5 CTSH UBE2U PSMA5 SFTPD CTSV KBTBD13 IGKC AP1S3 PSMC6 BTN3A1 CD1B DYNC1LI1 CD80 IGHV3-13 HLA-DQA1 TRBC1 PPP2R5B FBXO15 CD226 KLHL13 DYNLL1 RNF34 NFKBIB UBE4A UBE2Q2 CLEC2B PTPN11 IGKV1-17 VAV1 HLA-DMA PSMC3 ITCH KIR2DS1 HECW2 CD1D CALR ORAI2 PIK3CD DNM2 DYNC1H1 ITGAV KLHL5 PSMA1 PJA1 SEC24D FBXO22 LYN FBXL3 OSBPL1A CD36 IGLV3-21 TREML1 IGKV2-28 PSMD11 MADCAM1 ASB3 TYROBP LMO7 DCTN4 KLRB1 TUBA4A CD79A KIF4B MYD88 AKT2 PSMC5 PSMB5 ANAPC10 BTN2A1 LILRB4 CTSS UFL1 CLTC ACTR10 DTX3L RACGAP1 IFITM1 CD34 PSMD14 ZNRF2 IGLC1 LILRA3 ASB6 KLHL41 CD3D KIF15 MIB2 CLEC2D ASB7 ICOS PPP3R1 PSMF1 IGHV4-59 SKP2 ICAM5 ANAPC13 PPP2R5D OSCAR ERAP1 CD86 UBE2W NCR3 SEC24C BTN1A1 ICAM1 BTN2A2 WAS FBXW7 CD28 AP1M1 TAB2 IGKV1-5 FBXO40 CTLA4 PRR5 ICOSLG CTSE RNF6 CD1C HLA-DQA2 PRKN UBC IGHV4-34 VCAM1 IGLV3-19 KLHL20 BTLA DNM3 IGKV3-20 CAPZB CD74 HLA-G IGKV1D-33 ELOC PSMB1 SPSB2 TIRAP KIF3A SEC61B UBE2D3 TRIM36 ACTR1B KLHL2 SH2D1B ASB1 LILRB2 FBXL13 RCHY1 CTSK FKBP1A LNX1 FBXO6 TUBA1C PSMC1 KIF2B DYNC1I1 MAP3K7 MICA PRKG1 TRAV29DV5 CTSO ASB18 KIF26A RNF213 YWHAZ UBA1 UBE2E1 CD4 PPP2R5A SEC24A LCK FBXL19 TUBA4B PSME1 IGKV1-39 PPP2CA LILRA1 RASGRP1 IGLC6 KLC3 MAPKAP1 EVL ASB13 IGKV2-30 CAPZA2 HLA-DOA ITPR1 TUBA3E FBXL4 KRAS RNF7 CUL3 MEX3C AP2A2 SIAH2 FBXL12 IGHV3-48 KLRC1 RAPGEF4 TRAIP DCTN5 MYLIP FBXO2 CTSF UBA6 TRBV7-9 CD300LB TUBB4A CDC26 AP2S1 SLAMF7 ASB8 SOCS1 TUBB3 RAP1A TRIM32 ITGAL IGLV6-57 RBCK1 CUL7 PSMA2 CD22 NFKB1 VHL JAML CUL2 UBE2D4 RIPK2 CD207 ASB4 SIGLEC11 HCST PSMD10 HLA-A TRAV19 PIK3AP1 ICAM3 TUBB8 UBOX5 PAK2 PRKACG SPTBN2 KCTD7 PSMC2 SEC61A1 KLHL25 UBA7 VASP TRAC TREML2 ITGA4 SOS1 SIGLEC10 BTNL8 CCNF PSMB6 DZIP3 KLHL9 PSME3 NCF2 ZAP70 CDC23 CTSD MAP3K8 MALT1 TRIB3 CD200R1 PRKACA IGHV3-7 MAP3K14 TRIM39 IGHD TRPC1 IGHV3-30 RNF114 BLK AP1B1 WSB1 IGKV1D-12 CARD11 CTSL RBX1 HLA-DRB5 HLA-H UBE2E3 IGHV3-9 RNF123 RELA MKRN1 KLHL3 MRC2 CD300A AP2A1 ITGB5 NFATC2 SIGLEC5 KLHL22 IGKV2D-28 SIAH1 BTBD1 FBXW8 BTRC HLA-DQB2 LY96 CDC16 NPEPPS CBLB TRIM11 BCAP31 FBXO21 ARF1 KLRD1 SIGLEC9 ULBP3 FBXO9 B2M ANAPC5 SIPA1 KLRK1 UBAC1 GLYCAM1 TRAF7 PTPRC UBE2A UBA52 STIM1 RNF111 CD300C ZBTB16 RNF138 NFATC1 CD99 SAR1B FYB1 FBXL8 KIF20A MTOR IGKV3D-20 UBE3A COL17A1 ZNRF1 TREM1 PTPN22 UBE2B LGMN KIF3C KIF2C UBE2L6 KIR3DL2 GLMN LRRC41 UBE2E2 COL1A1 UBE2J2 PPL WWP1 KIFAP3 ASB15 KIF23 PSME4 CTSC PSMB8 TRAF6 ANAPC11 NCR3LG1 THEM4 IGHM NFATC3 CRTAM SEC31A LAIR1 LCP2 AKT3 FBXL7 LRR1 ASB14 IGKV3-11 LILRA4 RNF217 NEDD4 PSMB10 NECTIN2 UBR2 IGKV1D-39 TRBV12-3 RNF19B SNAP23 COL2A1 DCAF1 KIR2DL2 ICAM4 BTK GAN IKBKG RNF19A FBXO10 UBE3B FCGR1B IGLV1-40 HLA-DRB1 KLRF1 UBE2V1 TLR1 RAC1 CHUK PSMA6 PSMD6 FBXL5 HRAS PSMC4 SMURF1 PPIA CD3G CD1A KBTBD8 CDH1 CTSB IGKV2D-30 FBXL14 FZR1 RLIM IGKV1-16 CAPZA1 CANX TUBB4B CXADR IGHV4-39 ACTR1A HLA-C UBE2G2 ATG7 IGKV5-2 FYN UBE2M PAK3 LILRA5 TLR6 PPP2R1B IGKV2-29 CSK AHCYL1 SEC13 CDC27 HACE1 PRKCQ HLA-DOB UBE2H RNF220 UNKL PIK3R3 FBXO7 ASB2 PSMD2 PILRA SEC23A NFKBIE RNF4 FBXO44 STX4 IGLV2-14 DYNC1LI2 FBXL18 CD8A ASB9 TRIM69 SIGLEC1 IGKV1D-16 PSMB2 PSMD3 UBE2N CTSA PSMA7 SEC61A2 CD200 HLA-DRB3 LTN1 RAPGEF3 ELOB PPP2CB TRIM50 CUL1 RNF126 TLR2 UBE2V2 RASGRP2 ANAPC1 UBE3D PTEN COL3A1 PSMB4 ITGB1 NCK1 AP2M1 TUBB2B IGLV7-43 HECTD2 TUBA1A PSMB11 KIR2DS2 DYNC1I2 IGHV1-69 IGHV3-53 AP1G1 TRIM41 TRIM71 DET1 CBLL2 ULBP1 IGLV1-47 TRIM21 PSMD13 FBXO4 CD81 IGLV2-8 SIGLEC12 KIF22 IGHV3-33 REL TRAT1 KIF11 TAPBP PIK3CB PILRB ANAPC2 ASB5 KLHL11 FCGR1A PSMD9 IFI30 TREM2 KIF2A SLAMF6 CD33 C3 CD19 ASB10 CD300LG VAMP3 CDC20 LNPEP IGLC7 PSMA8 KEAP1 TLR4 ANAPC7 CD300E PPP2R5C PJA2 DCTN3 BTNL2 HLA-F TAP1 PPP2R1A HLA-E TUBB2A UBE2G1 HSPA5 FBXO31 TRIM63 FBXW4 ITPR3 RAET1E ANAPC4 SOCS3 ERAP2 SH2D1A RNF25 HUWE1 TUBA8 RAP1GAP UBE2J1 CD101 YES1 KIF18A PDCD1 THOP1 KLRG1 IGHV3-23 UBA3 SIGLEC6 AP2B1 AREL1 TUBB1 ITPR2 PSMB9 CLTA CD96 ORAI1 TRAV8-4 INPP5D BTNL9 RBBP6 PDPK1 IGLV2-23 CUL5 SH3RF1 CLEC4G DYNLL2 SKP1 KLHL21
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Hierarchy Landscape

The following plot represents the hierarchical landscape of 'Adaptive Immune System'. The hierarchical tree allows to click on the pathways with children (black border) and continue the exploration. All nodes are colored by their source (click on the map for the legend) and cross-link to the original pathway page.

Sub-Pathways

About

ComPath is developed and maintained in an academic capacity by Daniel Domingo-Fernández and Charles Tapley Hoyt at the Fraunhofer SCAI Department of Bioinformatics. This web application relies on data loaded from KEGG, Reactome, and WikiPathways Restful APIs, as well as MSigDB. More information here.