Cytokine Signaling in Immune system - Pathway Page
Name Cytokine Signaling in Immune system
Resource Reactome
Genes IGHG1 STAT6 HMGB1 CSF1R IFI27 IL26 IRAK1 PSMC1 EDA RNASEL RELB PIAS1 SOX2 TRIM48 IKBKG HSPA8 MAP3K8 PTPN9 PSMA2 IL17RA SNAP25 IL17RC CXCL10 CD70 TPR TNFRSF4 IFITM2 PSMB5 PSMD11 UBE2N PRTN3 IL15RA NKIRAS2 HCK TOLLIP IFI30 B2M MAPK8 MAP2K3 EGR1 CLCF1 IL2RB HNRNPF PPP2R1A DUSP6 IFNA16 IFNG SQSTM1 VAV1 PSMB11 TNF HLA-DRB3 HSP90AA1 VEGFA CNTF IL9R NEDD4 IFNAR1 IL36G VRK3 TRIM22 PRKCD IFNA2 ADAR JAK2 ISG20 HLA-DRA IL16 IL37 IL5RA RAG2 TEC TRIM29 PSMB8 CD4 CCL22 LIFR TNFRSF11A PELI2 NFKB1 MIF IL1R2 IL1RL1 BOLA2 PDCD4 CHUK KPNB1 IRAK2 IFNA8 TRIM14 CNTFR EIF4A2 IRAK3 CSF3R MAPK14 SEM1 BST2 IL27 HLA-DRB4 LYN TWIST1 IRF8 IL36RN DUSP7 ANXA1 CSH1 IRS1 OPRM1 IFNL3 TNFSF12 PELI1 CD40 IRF1 SP100 TP53 PTPN20 STAT5B IL34 IL23A OSMR FN1 GBP6 F13A1 IKBKB RHOU IL27RA PSMB2 PIK3R3 IFNGR2 MT2A LAMA5 PSMC5 IRF4 ITGB2 HLA-DPB1 IL20RA HLA-DQA2 HIST1H3A RSAD2 INPPL1 IL13RA1 CCL11 ZEB1 S100B NANOG PSMA3 MAP2K4 CEBPD NFKBIA TNFRSF12A PTK2B CD27 PSMD10 LBP TNFSF14 GH1 MMP9 EIF2AK2 MCL1 USP18 TNFRSF13B NFKBIB PPP2CA FASLG PELI3 PIM1 EIF4G1 TRIM31 JAK1 IL4R NUP88 TNFRSF14 AAAS TSLP PIK3R1 IRF5 CCL2 IL17RE BATF PRLR GBP1 PSMA1 HNRNPA2B1 SDC1 PTPN2 PSMD6 IL24 AKT1 IL36B MX2 IL17C NUP98 CCL3 ALOX5 PSMB9 KPNA3 HLA-DQB1 KPNA4 MAP2K6 TRIM17 MYD88 POMC IL7R IFITM1 EIF4G3 SOD2 EDARADD PITPNA IL17A TAB3 HLA-A PTPN6 PTPN12 YES1 EIF4G2 OAS1 PSMB7 HSP90B1 CCND1 TRIM34 TRIM8 CSF1 LCN2 IL1A TNFSF13B IL11 SUMO1 CXCL1 LCK IFI6 IL1RAPL1 RPS6KA2 TRAF6 JUNB UBE2V1 UBE2M IRF6 RPS27A NUP153 CSF2RA CDKN1A FLT3LG TYK2 TNFRSF1A TNFRSF9 HLA-DRB5 IL20RB MAPKAPK2 CD40LG TCP1 OAS2 GBP7 PML TNFRSF13C NUP85 CANX SNRPA1 SKP1 IL13 MAPK9 ISG15 IL9 RAP1B IL6ST ALOX15 PSMC2 TNFSF8 CNN2 TRIM2 IL2RA CIITA PSMB6 CCL3L1 PSMD3 HGF IRF2 P4HB UBB TRAF2 CRLF2 IFI35 SIGIRR TNFRSF1B IL22RA1 PAK2 OPRD1 EDAR MTAP PPP2R1B RAE1 TNFRSF18 KPNA1 BCL2 PIK3CB EIF4E2 STAT3 TNFRSF6B IL1R1 NUP37 IFIT3 FSCN1 INPP5D ITGAM ELK1 IL17RB KPNA7 PRL CA1 FGF2 IGHE IFNB1 RELA IL10RB IL3RA NUP188 MEF2C TRIM25 IFNA17 IFIT2 CD86 TRIM10 MUC1 MAPK1 IL4 TNFRSF11B PSMC6 FLNB IL1RL2 MAPKAPK3 IL1B MID1 TRIM38 BIRC5 IL18BP CUL1 PPP2CB MAP2K7 TBK1 SMARCA4 JAK3 PSMB3 STAT1 RPS6KA3 GSTA2 CCR5 SAMHD1 PSMD5 PTPN18 GBP5 PIK3CD IL12B TXLNA STAT4 PTPN5 PSME2 STAT2 IL33 NUP43 UBE2L6 HLA-H UBC RALA PSMA7 NUP133 IFITM3 RPS6KA5 CD80 GATA3 LGALS9 MAPK3 FYN HLA-E PSMA5 IL18RAP HLA-B TGFB1 GHR IL13RA2 VIM EDA2R TNFSF4 FCGR1A SYK IL12RB1 UBA7 IFNA14 ANXA2 PSMD7 IL1RN IL3 PSMB1 NUP54 TRIM26 PSMA4 TRIM3 TRIM5 TNFRSF25 TNFSF13 IL22 CCL20 CRK RAPGEF1 PIK3R2 TALDO1 NDN PTGS2 RBX1 UBA52 FOXO1 MMP1 NOD2 SOS2 IL1RAP IFNL1 HAVCR2 CCL19 ADAM17 TNFRSF8 MMP2 PTPN1 IGHG4 XAF1 FBXW11 FOXO3 IP6K2 PRKACA TNFSF11 IL21 TIMP1 BCL6 FCGR1B IL6R HSPA9 NUP58 TAB1 RIPK2 PTAFR CFL1 SHC1 CDC42 TNFRSF17 IL23R PSMD9 IL12A ICAM1 IL7 IFNGR1 BRWD1 NUP93 MYC RPS6KA1 PPIA HLA-DRB1 SOD1 FOS NCAM1 TRIM35 LIF IL1F10 STX3 CCR1 AGER MAP3K7 GBP3 IL10 NUP210 APP FPR1 STX4 SEH1L SH2B1 IFNA5 NUP205 PSME4 EIF4A3 HLA-DQB2 KPNA5 IFNL2 SOCS5 MAPK10 HLA-DPA1 CBL IL31RA IL18 MX1 IL18R1 IL2RG GH2 IFNA21 CAMK2D OASL PPM1B TRIM68 YWHAZ CAPZA1 CSF3 EBI3 CD44 SOCS1 GRB2 MAPK11 HLA-F KPNA2 SAA1 TAB2 GBP4 IL21R SMAD3 POU2F1 IL15 MAP2K1 IL5 STX1A IL17F PSMB10 ITGAX IL6 IRAK4 EIF4E MSN NUP160 PPP2R5D STXBP2 CASP1 OSM MAPK7 NUP35 PSMF1 PSMD4 IRF9 AIP VCAM1 ARIH1 COL1A2 TRIM6 TNFSF15 IFNA13 PTPRZ1 HNRNPDL S100A12 IRS2 BIRC2 PSME1 MEF2A CAMK2G CRKL NFKB2 NUP155 IL12RB2 LMNB1 NOS2 SERPINB2 NUP62 GBP2 TNIP2 PTPN13 CXCL2 PTPN7 IL19 TNFSF18 STAT5A CCL5 NOD1 ATF2 POM121C PTPN14 TRAF3 TNFSF9 IFNA6 PTPN23 MAP3K14 IL10RA HMOX1 HIF1A NUP50 UBE2E1 FCER2 IL36A SOCS2 CCL4 IRF7 CCR2 GSTO1 ITGB1 RAG1 VAMP7 BCL2L1 IFNLR1 LTBR CASP3 HIST2H3D HLA-C PSMA8 DDX58 RORA PSMD1 IFNAR2 LTA ARF1 PSMD13 PSMD2 JUN PSMC3 IFNA4 ABCE1 IFNA7 HLA-G TRIM62 TRIM21 DUSP3 CRLF1 IFIT1 DUSP4 POM121 EIF4A1 NUPL2 LTB PLCG1 IL32 GAB2 CD36 IRF3 ATF1 IL31 CXCL8 USP41 CSF2RB PIN1 IL22RA2 PIK3CA MAP3K3 HLA-DQA1 SOS1 CREB1 MMP3 PSMC4 SOCS3 IFNA10 RANBP2 HERC5 CAMK2A CAMK2B S1PR1 IL20 NKIRAS1 LCP1 FLT3 CSF2 TRIM46 OAS3 BIRC3 BTRC PSMB4 PSMA6 TRIM45 VAMP2 NUP107 IL2 PTPN4 EIF4E3 BLNK UBA3 IL25 CTF1 RORC IL11RA CISH NUP214 NDC1 RPLP0 PSMD8 PSME3 PSMD12 PSMD14 MAOA PTPN11
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Hierarchy Landscape

The following plot represents the hierarchical landscape of 'Cytokine Signaling in Immune system'. The hierarchical tree allows to click on the pathways with children (black border) and continue the exploration. All nodes are colored by their source (click on the map for the legend) and cross-link to the original pathway page.

Equivalent Pathways
Sub-Pathways

About

ComPath is developed and maintained in an academic capacity by Daniel Domingo-Fernández and Charles Tapley Hoyt at the Fraunhofer SCAI Department of Bioinformatics. This web application relies on data loaded from KEGG, Reactome, and WikiPathways Restful APIs, as well as MSigDB. More information here.