Drug metabolism - cytochrome P450 - Homo sapiens (human) - Pathway Page
Name Drug metabolism - cytochrome P450 - Homo sapiens (human)
Resource KEGG
Genes ALDH3A1 AOX1 CYP2E1 ALDH3B2 UGT1A9 MGST3 GSTA1 ADH6 UGT2B7 CYP2D6 CYP2C19 GSTM4 ADH4 ADH1A UGT1A7 FMO2 GSTT2 UGT2A2 GSTO1 GSTA5 CYP2B6 GSTM3 CYP3A4 HPGDS UGT1A5 GSTA3 FMO3 MGST1 GSTT2B GSTM5 CYP2C8 ADH1C UGT1A3 ADH7 FMO5 CYP3A5 GSTT1 GSTP1 UGT2B28 UGT1A1 ALDH1A3 GSTO2 GSTK1 ALDH3B1 GSTA4 CYP1A2 CYP2A6 UGT1A4 UGT2B15 CYP2C9 GSTA2 UGT2A1 UGT2B17 UGT1A8 UGT1A6 GSTM1 FMO1 UGT2A3 ADH1B MGST2 UGT2B4 UGT2B10 ADH5 GSTM2 UGT2B11 CYP2D7 UGT1A10 MAOA FMO4 MAOB
Size 70
Hierarchy Landscape

The following plot represents the hierarchical landscape of 'Drug metabolism - cytochrome P450 - Homo sapiens (human)'. The hierarchical tree allows to click on the pathways with children (black border) and continue the exploration. All nodes are colored by their source (click on the map for the legend) and cross-link to the original pathway page.

MetabolismAdipocytokine signaling pathwayAlanine, aspartate and glutamate metabolismAldosterone synthesis and secretionAmino sugar and nucleotide sugar metabolismAminoacyl-tRNA biosynthesisArginine and proline metabolismArginine biosynthesisAscorbate and aldarate metabolismBiosynthesis of amino acidsBiosynthesis of unsaturated fatty acidsButanoate metabolismCaffeine metabolismCarbon metabolismCholesterol metabolismCortisol synthesis and secretionCysteine and methionine metabolismD-Arginine and D-ornithine metabolismD-Glutamine and D-glutamate metabolismDrug metabolism - cytochrome P450Drug metabolism - other enzymesEther lipid metabolismFatty acid biosynthesisFatty acid degradationFatty acid elongationFatty acid metabolismFolate biosynthesisFructose and mannose metabolismGlycerolipid metabolismGlycerophospholipid metabolismGlycine, serine and threonine metabolismGlycolysis / GluconeogenesisGlycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfateGlycosaminoglycan biosynthesis - heparan sulfate / heparinGlycosaminoglycan biosynthesis - keratan sulfateGlycosaminoglycan degradationGlyoxylate and dicarboxylate metabolismHistidine metabolismLinoleic acid metabolismLipoic acid metabolismNeomycin, kanamycin and gentamicin biosynthesisNicotinate and nicotinamide metabolismNitrogen metabolismOne carbon pool by folateOther glycan degradationOvarian steroidogenesisOxidative phosphorylationPantothenate and CoA biosynthesisPentose and glucuronate interconversionsPeroxisomePhenylalanine metabolismPhenylalanine, tyrosine and tryptophan biosynthesisPhosphatidylinositol signaling systemPhosphonate and phosphinate metabolismPorphyrin and chlorophyll metabolismPrimary bile acid biosynthesisPropanoate metabolismRetinol metabolismSelenocompound metabolismStarch and sucrose metabolismSteroid biosynthesisSteroid hormone biosynthesisSulfur metabolismSynthesis and degradation of ketone bodiesTaurine and hypotaurine metabolismTerpenoid backbone biosynthesisThermogenesisThiamine metabolismTyrosine metabolismUbiquinone and other terpenoid-quinone biosynthesisValine, leucine and isoleucine biosynthesisValine, leucine and isoleucine degradationVitamin B6 metabolismalpha-Linolenic acid metabolismbeta-Alanine metabolismAcetylcholine SynthesisAflatoxin B1 metabolismAlanine and aspartate metabolismAmino Acid metabolismAmino acid conjugation of benzoic acidArachidonate Epoxygenase / Epoxide HydrolaseArylamine metabolismBenzene metabolismBenzo(a)pyrene metabolismBiogenic Amine SynthesisBiosynthesis and regeneration of tetrahydrobiopterin (BH4) and catabolism of phenylalanine, including diseasesButyrate-induced histone acetylationCaffeine and Theobromine metabolismCholesterol BiosynthesisCocaine metabolismCodeine and Morphine MetabolismColchicine Metabolic PathwayComposition of Lipid ParticlesCori CycleDegradation pathway of sphingolipids, including diseasesDiclofenac Metabolic PathwayDopamine metabolismEicosanoid SynthesisEnergy MetabolismEstrogen metabolismFatty Acid Beta OxidationFatty Acid BiosynthesisFatty Acid Omega OxidationFelbamate MetabolismFluoropyrimidine ActivityFolate MetabolismGanglio Sphingolipid MetabolismGlobo Sphingolipid MetabolismGlucocorticoid and Mineralcorticoid MetabolismGlutathione metabolismGlycolysis and GluconeogenesisGut-Liver Indole MetabolismHIF1A and PPARG regulation of glycolysisHeroin metabolismIron metabolism in placentaKennedy pathway from SphingolipidsLidocaine metabolismMetabolism of Spingolipids in ER and Golgi apparatusMetabolism of Tetrahydrocannabinol (THC)Mitochondrial LC-Fatty Acid Beta-OxidationNAD Biosynthesis II (from tryptophan)NAD+ biosynthetic pathwaysNAD+ metabolismNicotine MetabolismNuclear Receptors in Lipid Metabolism and ToxicityOne Carbon MetabolismOne carbon donorOne carbon metabolism and related pathwaysPPAR Alpha PathwayPPAR signaling pathwayPeroxisomal beta-oxidation of tetracosanoyl-CoAPhase I biotransformations, non P450Polyol PathwayProstaglandin Synthesis and RegulationPyrimidine metabolismSelenium Metabolism and SelenoproteinsSteroid BiosynthesisSulfation Biotransformation ReactionTamoxifen metabolismTrans-sulfuration and one carbon metabolismTrans-sulfuration pathwayTryptophan catabolism leading to NAD+ productionTryptophan metabolismUrea cycle and metabolism of amino groupsValproic acid pathwayVitamin A and Carotenoid MetabolismVitamin B12 Metabolism
Super-Pathways
Sub-Pathways

About

ComPath is developed and maintained in an academic capacity by Daniel Domingo-Fernández and Charles Tapley Hoyt at the Fraunhofer SCAI Department of Bioinformatics. This web application relies on data loaded from KEGG, Reactome, and WikiPathways Restful APIs, as well as MSigDB. More information here.